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Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
ARL67156 (FPL 67156) trisodium hydrate is a selective ecto-ATPase inhibitor. ARL67156 trisodium hydrate is a competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with K i s of 11, 18 and 12 μM, respectively. ARL67156 trisodium hydrate can be used
Appearance:Solid
IC50& Target:Ki: 11 μM (NTPDase1), 18 μM (NTPDase3), 12 μM (NPP1)
In Vitro:ARL67156 trisodium hydrate (1-100 μM) potentiates neurogenic contractions in a concentration-dependent manner. ARL67156 trisodium hydrate (10 μg/mL, 24 h) increases the surface expression of CXCR3 on ATP-treated HMC-1 cells. ARL67156 trisodium h
In Vivo:ARL67156 trisodium hydrate (1.1 μg/kg/day, administered with osmotic pumps implanted subcutaneously, for 28 days) prevents the development of calcific aortic valve disease in Warfarin (HY-B0687)-treated rats. ARL67156 trisodium hydrate (intraperitone
Biological Activity:ARL67156 (FPL 67156) trisodium hydrate is a selective ecto-ATPase inhibitor. ARL67156 trisodium hydrate is a competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with K i s of 11, 18 and 12u2009μM, respectively. ARL67156 trisodium hydrate can be u
| Peso molecular | 834.61 |
|---|
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