Determine the necessary mass, volume, or concentration for preparing a solution.
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Moligand™, analytical standard, ≥98% Analytical standard,Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 23 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| ALogP | 3.1 |
|---|
| Sonrisas canónicas | CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC)C |
|---|---|
| IUPAC Name | (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane |
| InChIKey | SXYIRMFQILZOAM-HVNFFKDJSA-N |
| INCHI | 1S/C16H26O5/c1-9-5-6-12-10(2)13(17-4)18-14-16(12)11(9)7-8-15(3,19-14)20-21-16/h9-14H,5-8H2,1-4H3/t9-,10-,11+,12+,13+,14-,15-,16-/m1/s1 |
| Isómeros SMILES | C[C@@H]1CC[C@H]2[C@H]([C@H](O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)OC)C |
| Peso molecular | 298.38 |
| Reaxy-Rn | 9350503 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9350503&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lipids and lipid-like molecules |
| Clase | Prenol lipids |
| Subclass | Sesquiterpenoids |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Artemisinins |
| Alternative Parents | Oxepanes Trioxanes Oxanes Dialkyl peroxides Oxacyclic compounds Acetals Hydrocarbon derivatives |
| Molecular Framework | Aliphatic heteropolycyclic compounds |
| Substituents | Artemisinin skeleton - Oxepane - 1,2,4-trioxane - Oxane - Dialkyl peroxide - Oxacycle - Organoheterocyclic compound - Acetal - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aliphatic heteropolycyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as artemisinins. These are sesquiterpenoids originally isolated from the herb Artemisia annua. Their structure is based on artemisinin, a tetracyclic compound that contains a 1,2-dioxepane fused to an octahydrobenzopyran moiety. The internal peroxide bridge is believed to be a key to the mode of action of artemisinins. |
| External Descriptors | semisynthetic derivative - sesquiterpenoid - artemisinin derivative - cyclic acetal - organic peroxide |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | Mar 09, 2023 | A107446 |
| Rotación específica [α] | 170° (C=1,EtOH) |
|---|---|
| Punto de fusión (°C) | 86-88°C |
| Peso molecular | 298.370 g/mol |
| XLogP3 | 3.100 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 1 |
| Exact Mass | 298.178 Da |
| Monoisotopic Mass | 298.178 Da |
| Topological Polar Surface Area | 46.200 Ų |
| Heavy Atom Count | 21 |
| Formal Charge | 0 |
| Complexity | 429.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 8 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Jingjing Zhen, Faguang Ma, Rongxin Lin, Ming Yan, Yilin Wu. (2023) Porous MOFs-based self-assembled membrane with specific rebinding nanocages for selective recognition and separation at molecular level. DESALINATION, [PMID:] [10.1016/j.desal.2023.117124] |
| 2. Weibai Bian, Ruixuan Zhang, Xiaohui Chen, Chuanxun Zhang, Minjia Meng. (2023) Three-Dimensional Porous PVDF Foam Imprinted Membranes with High Flux and Selectivity toward Artemisinin/Artemether. MOLECULES, 28 (21): (7452). [PMID:37959871] [10.3390/molecules28217452] |
| 3. Jing Yan, Faguang Ma, Yilin Wu. (2023) Permselective and transparent wooden membrane with artemisinin-imprinted nanocages based on a MOFs@C3N4 self-assembly design. Materials Today Nano, [PMID:] [10.1016/j.mtnano.2023.100369] |
| 4. Minjia Meng, Yi Li, Hui Peng, Binrong Li, Chuanxun Zhang, Jiajia Ren, Qingluola Ren, Yan Liu, Jianming Pan. (2023) Hydrophilic imprinted MnO2 nanowires “coating” membrane with ultrahigh adsorption capacity for highly selective separation of Artemisinin/Artemether. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2023.143020] |
| 5. Qiong Xu, Yin-Yan Duan, Ming Pan, Qi-Wang Jin, Jian-Ping Tao, Si-Yang Huang. (2023) In Vitro Evaluation Reveals Effect and Mechanism of Artemether against Toxoplasma gondii. Metabolites, 13 (4): (476). [PMID:37110135] [10.3390/metabo13040476] |
| 6. Jing Yan, Kaicheng Zhang, Faguang Ma, Hang Cui, Yilin Wu. (2023) Scalable basswood-based PDA/GO-embedded self-assembly membrane within multilayered artemisinin-imprinted nanocage for high-selectivity cascading adsorption and transport. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2023.142277] |
| 7. Fang Lu, Fa Zhang, Jingqi Qian, Tingting Huang, Liping Chen, Yilin Huang, Baomin Wang, Liwang Cui, Suqin Guo. (2022) Preparation and application of a specific single-chain variable fragment against artemether. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, [PMID:36049377] [10.1016/j.jpba.2022.115020] |
| 8. Jianxin Jia, Qi Kang, Shunzhi Liu, Yabin Song, Florence Susan Wong, Yingkun Qiu, Mingyu Li. (2021) Artemether and aspterric acid induce pancreatic alpha cells to transdifferentiate into beta cells in zebrafish. BRITISH JOURNAL OF PHARMACOLOGY, 179 (9): (1962-1977). [PMID:34871457] [10.1111/bph.15769] |
| 9. Sennan Qiao, Hansi Zhang, Fei Sun, Zhenyan Jiang. (2021) Molecular Basis of Artemisinin Derivatives Inhibition of Myeloid Differentiation Protein 2 by Combined in Silico and Experimental Study. MOLECULES, 26 (18): (5698). [PMID:34577169] [10.3390/molecules26185698] |
| 10. Xuerong Dong, Xiang Zhang, Manyuan Wang, Liwei Gu, Jing Li, Muxin Gong. (2021) Heparin-decorated nanostructured lipid carriers of artemether-protoporphyrin IX-transferrin combination for therapy of malaria. INTERNATIONAL JOURNAL OF PHARMACEUTICS, [PMID:34144137] [10.1016/j.ijpharm.2021.120813] |
| 11. Mengqi Bai, Li Qiang, Minjia Meng, Binrong Li, Suao Wang, Yilin Wu, Li Chen, Jiangdong Dai, Yan Liu, Jianming Pan. (2020) Upper surface imprinted membrane prepared by magnetic guidance phase inversion method for highly efficient and selective separation of Artemisinin. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2020.126899] |
| 12. Yilin Wu, Wendong Xing, Minjia Meng, Jian Lu, Faguang Ma, Jia Gao, Xinyu Lin, Chao Yu. (2020) Multiple-functional molecularly imprinted nanocomposite membranes for high-efficiency selective separation applications: An imitated core-shell TiO2@PDA-based MIMs design. COMPOSITES PART B-ENGINEERING, [PMID:] [10.1016/j.compositesb.2020.108123] |
| 13. Yao Yuyuan, Guo Qinglong, Cao Yue, Qiu Yangmin, Tan Renxiang, Yu Zhou, Zhou Yuxin, Lu Na. (2018) Artemisinin derivatives inactivate cancer-associated fibroblasts through suppressing TGF-β signaling in breast cancer. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 37 (1): (1-14). [PMID:30477536] [10.1186/s13046-018-0960-7] |
| 14. Jiaqin Wang, Yanying Zhou, Man Wang, Wentao Bi, Hongli Li, David Da Yong Chen. (2018) High-Throughput Analysis for Artemisinins with Deep Eutectic Solvents Mechanochemical Extraction and Direct Analysis in Real Time Mass Spectrometry. ANALYTICAL CHEMISTRY, [PMID:29381342] [10.1021/acs.analchem.7b04060] |
| 15. Jie-Hua Shi, Kai-Li Zhou, Yan-Yue Lou, Dong-Qi Pan. (2017) Multi-spectroscopic and molecular modeling approaches to elucidate the binding interaction between bovine serum albumin and darunavir, a HIV protease inhibitor. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:28753530] [10.1016/j.saa.2017.07.040] |
| 16. Shoubing Wang, Ziran Xu. (2016) Effects of Dihydroartemisinin and Artemether on the Growth, Chlorophyll Fluorescence, and Extracellular Alkaline Phosphatase Activity of the Cyanobacterium Microcystis aeruginosa. PLoS One, 11 (10): (e0164842). [PMID:27755566] [10.1371/journal.pone.0164842] |
| 17. Yilin Wu, Xinlin Liu, Minjia Meng, Peng Lv, Ming Yan, Xiao Wei, Hongji Li, Yongsheng Yan, Chunxiang Li. (2015) Bio-inspired adhesion: Fabrication of molecularly imprinted nanocomposite membranes by developing a hybrid organic–inorganic nanoparticles composite structure. JOURNAL OF MEMBRANE SCIENCE, [PMID:] [10.1016/j.memsci.2015.04.023] |
| 18. Yilin Wu, Ming Yan, Yongsheng Yan, Xinlin Liu, Minjia Meng, Peng Lv, Jianming Pan, Pengwei Huo, Chunxiang Li. (2014) Fabrication and Evaluation of Artemisinin-Imprinted Composite Membranes by Developing a Surface Functional Monomer-Directing Prepolymerization System. LANGMUIR, [PMID:25420213] [10.1021/la504336s] |
| 19. Junyan Wang, Minmin Huang, Haihong Hu, Lushan Yu, Su Zeng. (2014) Pregnane X receptor-mediated transcriptional activation of UDP-glucuronosyltransferase 1A1 by natural constituents from foods and herbs. FOOD CHEMISTRY, [PMID:24996308] [10.1016/j.foodchem.2014.05.004] |
| 20. YiLin Wu, MinJia Meng, Xinlin Liu, Chunxiang Li, Min Zhang, Yanjun Ji, Fengquan Sun, Zhihui He, YongSheng Yan. (2014) Efficient one-pot synthesis of artemisinin-imprinted membrane by direct surface-initiated AGET-ATRP. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2014.05.001] |
| 21. Shengli Quan, Jinhua Li, Shuxian Ding, Xingjie Zhuo, Yuanxiao Yang, Qin Li. (2025) Artemether exerts neuroprotective effect in Parkinson's disease through the PI3K/Akt/GSK-3β signaling pathway. EUROPEAN JOURNAL OF PHARMACOLOGY, [PMID:40157705] [10.1016/j.ejphar.2025.177566] |
| 22. Fang Lu, Xiqun Wu, Fa Zhang, Jiaqiang Wu, Zhaodong Yuan, Baomin Wang, Guiyu Tan, Suqin Guo. (2024) Comparison of single-chain variable fragments and monoclonal antibody against dihydroartemisinin. JOURNAL OF IMMUNOLOGICAL METHODS, [PMID:39059746] [10.1016/j.jim.2024.113728] |
| 23. Weixing Zeng, Yawen Yang, Jia Xiong, Cui Li, Yang He, Zhihao Liang, Yongwen He. (2025) Artemisinin derivatives maintain fibroblast normalization by acting on tumor-stroma interactions in oral tongue squamous cell carcinoma. American Journal of Cancer Research, 15 (6): (2657). [PMID:40667553] [10.62347/EHVJ7118] |
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