Aurothiomalate (disodium) is a TRPA1 inhibitor. Aurothiomalate (disodium) inhibits NF-κB activation and iNOS expression. Aurothiomalate (disodium) promotes M2 transformation of macrophages and increases the expression of TREM-2 and arginase-1. Aurothiomalate (disodium) can be used in the study of liver fibrosis/cirrhosis and arthritis
| Sonrisas canónicas | C(C(C(=O)[O-])[S-])C(=O)[O-].[Na+].[Na+].[Au+] |
|---|---|
| IUPAC Name | disodium;gold(1+);2-sulfidobutanedioate |
| InChIKey | VXIHRIQNJCRFQX-UHFFFAOYSA-K |
| INCHI | 1S/C4H6O4S.Au.2Na/c5-3(6)1-2(9)4(7)8;;;/h2,9H,1H2,(H,5,6)(H,7,8);;;/q;3*+1/p-3 |
| Isómeros SMILES | C(C(C(=O)[O-])[S-])C(=O)[O-].[Na+].[Na+].[Au+] |
| WGK Alemania | 3 |
| CAS alternativo | 74916-57-7 |
| Peso molecular | 390.08 |
| Reaxy-Rn | 14647662 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14647662&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lipids and lipid-like molecules |
| Clase | Fatty Acyls |
| Subclass | Fatty acids and conjugates |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Thia fatty acids |
| Alternative Parents | Dicarboxylic acids and derivatives Carboxylic acid salts Organic transition metal salts Carboxylic acids Organosulfur compounds Organic sodium salts Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Thia fatty acid - Dicarboxylic acid or derivatives - Carboxylic acid salt - Carboxylic acid derivative - Carboxylic acid - Organic transition metal salt - Organic alkali metal salt - Hydrocarbon derivative - Organosulfur compound - Organooxygen compound - Organic oxide - Carbonyl group - Organic salt - Organic sodium salt - Organic oxygen compound - Aliphatic acyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as thia fatty acids. These are fatty acid derivatives obtained by insertion of a sulfur atom at specific positions in the chain. |
| External Descriptors | organic sodium salt |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 H2529406 | Certificate of Analysis | Aug 22, 2025 | G338205 |
| H2529407 | Certificate of Analysis | Aug 22, 2025 | G338205 |
| H2529408 | Certificate of Analysis | Aug 22, 2025 | G338205 |
| H2407353 | Certificate of Analysis | Apr 17, 2024 | G338205 |
| H2407354 | Certificate of Analysis | Apr 17, 2024 | G338205 |
| Solubilidad | Soluble in water. Insoluble in alcohol, and ether. |
|---|---|
| Sensibilidad | Moisture sensitive |
| Peso molecular | 390.080 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 1 |
| Exact Mass | 389.921 Da |
| Monoisotopic Mass | 389.921 Da |
| Topological Polar Surface Area | 81.300 Ų |
| Heavy Atom Count | 12 |
| Formal Charge | 0 |
| Complexity | 126.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 4 |
