Avertin (Ready-to-Use, for Mouse) - BioReagent,ready-to-use,sterile,1.25% , CAS No.75-80-9

CAS: 75-80-9 Cat. No.: R1511178 Peso molecular: 282.76 Número EC: 200-903-1 PubChem CID: 6400

GRADE & PURITY BioReagent, Ready-to-use, Sterile, 1.25%

Synonyms

Avertin | Ready-to-Use Avertin for Mouse | 1.25% Avertin | Tribromoethanol for Ready Use (Mouse)

Storage

Store at 2-8°C,Protected from light

Shipped In

Wet ice

Application

In Vivo Imaging, Nude Mouse Tumorigenicity Assay

Descripción general

  This product is a ready‑to‑use sterile anesthetic, with the active ingredient Tribromoethanol (TBE, also known as Avertin). It is a non‑controlled substance. This reagent has been recommended for anesthesia in surgical procedures related to transgenic mouse breeding, and is suitable for use in pregnant mice without affecting the pregnancy process or fetal viability. It is administered via intraperitoneal injection, making it simple and convenient to use. The anesthetic takes effect in <5 minutes and lasts for 24–90 minutes. It is intended only for anesthesia in rodent mice.

Product Advantages

• Superior to chloral hydrate

• Suitable for anesthesia in pregnant mice

• Rapid onset: <5 minutes

• Long duration: 24–90 minutes

• Ethically approved and recognized in SCI‑indexed publications

Anesthesia Duration Validation

Strain	Age (weeks)	Injection Dose	Administration Route	Onset Time	Anesthesia Duration
C57BL/6	6-8	20 μL/g	Right intraperitoneal injection	<2 min	30-90 min
BALB/c	6-8	20 μL/g	Right intraperitoneal injection	<2 min	30-90 min

The above doses are based on our validation studies using common protocols. Actual dosage may need adjustment depending on mouse/rat age, strain, or individual variation. To extend anesthesia duration, a supplemental dose of one‑third of the initial dose may be administered. Users are advised to conduct pilot experiments according to their specific needs.

Precautions

1. After opening, it is recommended to use within 2 weeks. Prolonged storage may lead to precipitation or decomposition of components, reducing anesthetic efficacy or even causing peritonitis. Before use, always check the expiration date on the label and observe whether the solution has changed color or developed crystals. If crystals have formed, dissolve them in a 37°C water bath. Perform a pilot experiment before formal studies.

2. Recommended anesthetic doses:

• ~4‑week‑old mice: 16 µL/g

• ~6‑week‑old mice: 18 µL/g

• Mice ≥8 weeks: 20 µL/g

• (These are recommended starting doses; adjust according to actual conditions.)

To accelerate recovery, a heating pad may be used to raise the ambient temperature.

3. For research use only (non‑clinical research).

Specifications

Sinónimos

Avertin | Ready-to-Use Avertin for Mouse | 1.25% Avertin | Tribromoethanol for Ready Use (Mouse)

Especificaciones y pureza

BioReagent, ready-to-use, sterile, 1.25%

Estabilidad y almacenamiento

Store at 2-8℃ long term (12 months). Store in the dark.

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C, Protected from light

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

BioReagent, Ready-to-use, Sterile

Nombres e identificadores

• Isómeros SMILES: C(C(Br)(Br)Br)O
• WGK Alemania: 3
• RTECS: KM3675000
• PubChem CID: 6400
• Peso molecular: 282.76
• Reaxy-Rn: 1733249

Propiedades químicas y físicas

• Sensibilidad: Light-sensitive
• Punto de ebullición (°C): 94°C/11mmHg
• Punto de fusión (°C): 73°C-83.0 °C

Referencias

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