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· · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items AZ 6102 - Moligand™, 10mM in DMSO , Inhibitor of tankyrase, CAS No.1645286-75-4, Inhibitor of tankyrase
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO Synonyms
2-(4-(6-((3S,5R)-3,5-dimethylpiperazin-1-yl)-4-methylpyridin-3-yl)phenyl)-7-methyl-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one | AZ6102 | rel-2-[4-[6-[(3R,5S)-3,5-Dimethyl-1-piperazinyl]-4-methyl-3-pyridinyl]phenyl]-3,7-dihydro-7-methyl-4H-pyrrolo[2,3-d]pyrimidi
Storage
Protected from light,Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Why this grade Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Protected from light,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Sinónimos
2-(4-(6-((3S, 5R)-3, 5-dimethylpiperazin-1-yl)-4-methylpyridin-3-yl)phenyl)-7-methyl-3H-pyrrolo[2, 3-d]pyrimidin-4(7H)-one | AZ6102 | rel-2-[4-[6-[(3R, 5S)-3, 5-Dimethyl-1-piperazinyl]-4-methyl-3-pyridinyl]phenyl]-3, 7-dihydro-7-methyl-4H-pyrrolo[2, 3-d]pyrimidi
Especificaciones y pureza
Moligand™, 10mM in DMSO
Mecanismos bioquímicos y fisiológicos
Potent TNKS2 and TNKS1 inhibitor (IC50 values of 1 and 3 nM, respectively). The selectivity for TNKS1/2 is more than 100-fold higher than that of PARP-1, PARP-2 and PARP-6. Inhibits Wnt signaling in DLD-1 cells (IC50=5 nM).
Condiciones de almacenamiento de almacenamiento
Protected from light, Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Mecanismo de acción
Inhibitor of tankyrase
Nombres e identificadores Sonrisas canónicas CC1CN(CC(N1)C)C2=NC=C(C(=C2)C)C3=CC=C(C=C3)C4=NC5=C(C=CN5C)C(=O)N4 IUPAC Name 2-[4-[6-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-4-methylpyridin-3-yl]phenyl]-7-methyl-3H-pyrrolo[2,3-d]pyrimidin-4-one InChIKey WCPTUQOMNJBIET-CALCHBBNSA-N INCHI 1S/C25H28N6O/c1-15-11-22(31-13-16(2)27-17(3)14-31)26-12-21(15)18-5-7-19(8-6-18)23-28-24-20(25(32)29-23)9-10-30(24)4/h5-12,16-17,27H,13-14H2,1-4H3,(H,28,29,32)/t16-,17+ Isómeros SMILES C[C@@H]1CN(C[C@@H](N1)C)C2=NC=C(C(=C2)C)C3=CC=C(C=C3)C4=NC5=C(C=CN5C)C(=O)N4 PubChem CID 135905416 Peso molecular 428.53
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Clase Diazinanes Subclass Piperazines Intermediate Tree Nodes Not available Direct Parent Pyridinylpiperazines Alternative Parents N-arylpiperazines Phenylpyridines Pyrrolo[2,3-d]pyrimidines Dialkylarylamines Aminopyridines and derivatives Methylpyridines Pyrimidones Benzene and substituted derivatives Imidolactams N-methylpyrroles Heteroaromatic compounds Vinylogous amides Azacyclic compounds Dialkylamines Hydrocarbon derivatives Organic oxides Organooxygen compounds Molecular Framework Aromatic heteropolycyclic compounds Substituents Pyridinylpiperazine - N-arylpiperazine - 3-phenylpyridine - Pyrrolopyrimidine - Pyrrolo[2,3-d]pyrimidine - Dialkylarylamine - Methylpyridine - Pyrimidone - Aminopyridine - N-methylpyrrole - Pyridine - Imidolactam - Benzenoid - Substituted pyrrole - Pyrimidine - Monocyclic benzene moiety - Pyrrole - Heteroaromatic compound - Vinylogous amide - Secondary aliphatic amine - Azacycle - Secondary amine - Organooxygen compound - Organonitrogen compound - Organic oxide - Amine - Organic oxygen compound - Hydrocarbon derivative - Organic nitrogen compound - Aromatic heteropolycyclic compound Descripción This compound belongs to the class of organic compounds known as pyridinylpiperazines. These are compounds containing a pyridinylpiperazine skeleton, which consists of a pyridine linked (not fused) to a piperazine by a bond by a single bond that is not part of a ring. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Sensibilidad light sensitive Peso molecular 428.500 g/mol XLogP3 3.000 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 5 Rotatable Bond Count 3 Exact Mass 428.232 Da Monoisotopic Mass 428.232 Da Topological Polar Surface Area 74.600 Ų Heavy Atom Count 32 Formal Charge 0 Complexity 709.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 2 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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Reconstitution Calculator Reseñas Need help choosing the grade? Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
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