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AZD1979 - ≥98% , CAS No.1254035-84-1

CAS: 1254035-84-1 Cat. No.: A647822 Peso molecular: 462.50 PubChem CID: 49801838
COA
AZD1979 - ≥98% CAS No(1254035-84-1) by Aladdin Scientific
Disponible para pedir
GRADE & PURITY ≥98%
Synonyms
AZD 1979 [WHO-DD] | BDBM50159343 | DTXSID001106011 | (3-(4-(2-oxa-6-azaspiro[3.3]heptan-6-ylmethyl)phenoxy)azetidin-1-yl)(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)methanone | [5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]-[3-[4-(2-oxa-6-azaspiro[3.3]heptan-6-
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
5mg
A647822-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
340,90US$
10mg
A647822-10mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
540,90US$
25mg
A647822-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
1.060,90US$
50mg
A647822-50mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
1.700,90US$
100mg
A647822-100mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
2.700,90US$
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Descripción general Specifications Nombres e identificadores Documentation Advanced Data Taxonomic Classification Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Calculadoras de soluciones Reseñas
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

AZD1979 is a Melanin-concentrating hormone receptor 1 ( MCHr1 ) antagonist with an IC 50 of ~12 nM.

In Vivo

In DIO mice, initial AZD1979-mediate body weight loss is driven by decreasing food intake, but an additional component of preserving energy expenditure is apparent in pair-feeding and indirect calorimetry studies. AZD1979 also dose-dependently reduces body weight in dogs . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:IC50: ~12 nM (MCHr1)

Specifications

Sinónimos
AZD 1979 [WHO-DD] | BDBM50159343 | DTXSID001106011 | (3-(4-(2-oxa-6-azaspiro[3.3]heptan-6-ylmethyl)phenoxy)azetidin-1-yl)(5-(4-methoxyphenyl)-1, 3, 4-oxadiazol-2-yl)methanone | [5-(4-methoxyphenyl)-1, 3, 4-oxadiazol-2-yl]-[3-[4-(2-oxa-6-azaspiro[3.3]heptan-6-
Especificaciones y pureza
≥98%
Mecanismos bioquímicos y fisiológicos
AZD1979 is a Melanin-concentrating hormone receptor 1 ( MCHr1 ) antagonist with an IC 50 of ~12 nM.
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
ANTAGONIST
Pureza
≥98%
Nombres e identificadores
Sonrisas canónicasCOC1=CC=C(C=C1)C2=NN=C(O2)C(=O)N3CC(C3)OC4=CC=C(C=C4)CN5CC6(C5)COC6
IUPAC Name[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]-[3-[4-(2-oxa-6-azaspiro[3.3]heptan-6-ylmethyl)phenoxy]azetidin-1-yl]methanone
InChIKeyBKKPIQPFRAPEAY-UHFFFAOYSA-N
INCHI1S/C25H26N4O5/c1-31-19-8-4-18(5-9-19)22-26-27-23(34-22)24(30)29-11-21(12-29)33-20-6-2-17(3-7-20)10-28-13-25(14-28)15-32-16-25/h2-9,21H,10-16H2,1H3
Isómeros SMILES COC1=CC=C(C=C1)C2=NN=C(O2)C(=O)N3CC(C3)OC4=CC=C(C=C4)CN5CC6(C5)COC6
CAS alternativo 1254035-84-1
PubChem CID 49801838
Términos de entrada MeSH (3-(4-(2-oxa-6-azaspiro(3.3)heptan-6-ylmethyl)phenoxy)azetidin-1-yl)(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)methanone;AZD1979
Peso molecular 462.50

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClaseBenzene and substituted derivatives
SubclassPhenylmethylamines
Intermediate Tree Nodes Not available
Direct ParentPhenylmethylamines
Alternative Parents Phenoxy compounds  2-heteroaryl carboxamides  Methoxybenzenes  Benzylamines  Anisoles  Alkyl aryl ethers  Aralkylamines  Tertiary carboxylic acid amides  1,3,4-oxadiazoles  Heteroaromatic compounds  Trialkylamines  Oxetanes  Amino acids and derivatives  Azetidines  Oxacyclic compounds  Dialkyl ethers  Azacyclic compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Anisole - Benzylamine - Phenol ether - Phenylmethylamine - Methoxybenzene - Phenoxy compound - 2-heteroaryl carboxamide - Aralkylamine - Alkyl aryl ether - Heteroaromatic compound - Azole - 1,3,4-oxadiazole - Oxadiazole - Tertiary carboxylic acid amide - Azetidine - Carboxamide group - Tertiary aliphatic amine - Oxetane - Amino acid or derivatives - Tertiary amine - Ether - Dialkyl ether - Carboxylic acid derivative - Organoheterocyclic compound - Azacycle - Oxacycle - Organonitrogen compound - Organic nitrogen compound - Organooxygen compound - Organic oxygen compound - Amine - Organic oxide - Hydrocarbon derivative - Aromatic heteropolycyclic compound
DescripciónThis compound belongs to the class of organic compounds known as phenylmethylamines. These are compounds containing a phenylmethtylamine moiety, which consists of a phenyl group substituted by an methanamine.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
MCHR1 Tchem Melanin-concentrating hormone receptor 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
EPHX1 Tchem Epoxide hydrolase 1 (644 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCHR1 Tchem Melanin-concentrating hormone receptor 1 (5587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCHR2 Tchem Melanin-concentrating hormone receptor 2 (304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Cavia porcellus (23802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Canis familiaris (36305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasma (328 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
SolubilidadDMSO : 33.33 mg/mL (72.06 mM; ultrasonic and warming and heat to 60°C)
Peso molecular462.500 g/mol
XLogP32.000
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Exact Mass462.19 Da
Monoisotopic Mass462.19 Da
Topological Polar Surface Area90.200 Ų
Heavy Atom Count34
Formal Charge0
Complexity706.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculadoras de soluciones
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