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AZD3264 - 10mM in DMSO , CAS No.1609281-86-8

AZD3264 - 10mM in DMSO , CAS No.1609281-86-8

Name: AZD3264 - 10mM in DMSO , CAS No.1609281-86-8
Brand: Aladdin Scientific
SKU: A421932
Availability: InStock

CAS: 1609281-86-8 Cat. No.: A421932 Peso molecular: 441.5 PubChem CID: 91666658

COA

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AZD3264 - 10mM in DMSO CAS No(1609281-86-8) by Aladdin Scientific

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Disponible para pedir

GRADE & PURITY 10mM in DMSO

Synonyms

HY-19362 | CCG-269140 | NCGC00481403-01 | AC-33125 | 2-(carbamoylamino)-5-[4-(dimethyl-1,2-oxazol-4-yl)-2-[(3S)-pyrrolidin-3-yloxy]phenyl]thiophene-3-carboxamide | 1609281-86-8 | 2TT3S8GPB7 | C73048 | s7851 | AKOS030526605 | (S)-5-(4-(3,5-dimethylisoxazol

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general Specifications Propiedades del producto Nombres e identificadores Documentation Advanced Data Taxonomic Classification Estructura 3D Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Calculadoras de soluciones Reseñas

🧪

Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Information

AZD3264 is a novelIKK2inhibitor.

Targets

IKK2

In vitro

AZD3264, by inhibiting IKK2, prevents inﬂammatory conditions such as asthma, chronic pulmonary obstructive disorder (COPD) and rheumatoid arthritis.

Specifications

Sinónimos

HY-19362 | CCG-269140 | NCGC00481403-01 | AC-33125 | 2-(carbamoylamino)-5-[4-(dimethyl-1, 2-oxazol-4-yl)-2-[(3S)-pyrrolidin-3-yloxy]phenyl]thiophene-3-carboxamide | 1609281-86-8 | 2TT3S8GPB7 | C73048 | s7851 | AKOS030526605 | (S)-5-(4-(3, 5-dimethylisoxazol

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

AZD3264 is a novel IKK2 inhibitor.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Propiedades del producto

ALogP	1.235
Recuento HBD	4
Enlace rotable	6

Nombres e identificadores

Sonrisas canónicas	CC1=C(C(=NO1)C)C2=CC(=C(C=C2)C3=CC(=C(S3)NC(=O)N)C(=O)N)OC4CCNC4
IUPAC Name	2-(carbamoylamino)-5-[4-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[(3S)-pyrrolidin-3-yl]oxyphenyl]thiophene-3-carboxamide
InChIKey	NMFIXEFNQPDISY-ZDUSSCGKSA-N
INCHI	1S/C21H23N5O4S/c1-10-18(11(2)30-26-10)12-3-4-14(16(7-12)29-13-5-6-24-9-13)17-8-15(19(22)27)20(31-17)25-21(23)28/h3-4,7-8,13,24H,5-6,9H2,1-2H3,(H2,22,27)(H3,23,25,28)/t13-/m0/s1
Isómeros SMILES	CC1=C(C(=NO1)C)C2=CC(=C(C=C2)C3=CC(=C(S3)NC(=O)N)C(=O)N)O[C@H]4CCNC4
PubChem CID	91666658
Peso molecular	441.5

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Clase Thiophenes
    - Subclass Thiophene carboxylic acids and derivatives

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Clase	Thiophenes
Subclass	Thiophene carboxylic acids and derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Thiophene carboxamides
Alternative Parents	Phenoxy compounds Phenol ethers 2,3,5-trisubstituted thiophenes Alkyl aryl ethers Vinylogous amides Pyrrolidines Isoxazoles Heteroaromatic compounds Ureas Primary carboxylic acid amides Amino acids and derivatives Oxacyclic compounds Dialkylamines Azacyclic compounds Organic oxides Carbonyl compounds Hydrocarbon derivatives Organic anions
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Phenoxy compound - Phenol ether - 2,3,5-trisubstituted thiophene - Thiophene carboxamide - Alkyl aryl ether - Monocyclic benzene moiety - Benzenoid - Azole - Heteroaromatic compound - Isoxazole - Vinylogous amide - Pyrrolidine - Amino acid or derivatives - Carboxamide group - Urea - Primary carboxylic acid amide - Oxacycle - Carboxylic acid derivative - Secondary aliphatic amine - Ether - Azacycle - Secondary amine - Organic oxygen compound - Amine - Organic nitrogen compound - Carbonyl group - Organic oxide - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Organic anion - Aromatic heteromonocyclic compound
Descripción	This compound belongs to the class of organic compounds known as thiophene carboxamides. These are compounds containing a thiophene ring which bears a carboxamide.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Estructura 3D

Objetivos asociados (no humanos)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Certificados (CoA, COO, BSE/TSE y tabla de análisis)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Propiedades químicas y físicas

DMSO (mg/ml) Solubilidad máxima	88
DMSO (mM) Solubilidad máxima	199.3204983
Agua (mg/ml) Solubilidad máxima	＜1
Peso molecular	441.500 g/mol
XLogP3	2.200
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	6
Exact Mass	441.147 Da
Monoisotopic Mass	441.147 Da
Topological Polar Surface Area	174.000 Å²
Heavy Atom Count	31
Formal Charge	0
Complexity	670.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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