AZD7687 - Moligand™, ≥98% , Inhibitor of diacylglycerol O-acyltransferase 1, CAS No.1166827-44-6, Inhibitor of diacylglycerol O-acyltransferase 1

CAS: 1166827-44-6 Cat. No.: A128057 Peso molecular: 367.44 Número EC: 682-438-8
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
AZD7687 | AZD-7687 | DB14949 | 2-[4-[4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)phenyl]cyclohexyl]acetic acid | SCHEMBL5532381 | AZD 7687 | GTPL7827 | AKOS030526281 | 6QTJ9P2NYT | AZD 7687 [WHO-DD] | EN300-16131 | NCGC00378858-01 | SCHEMBL2252415 | 1166827-4
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1mg
A128057-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
139,90US$
5mg
A128057-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
439,90US$
10mg
A128057-10mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
779,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos
AZD7687 | AZD-7687 | DB14949 | 2-[4-[4-(6-carbamoyl-3, 5-dimethylpyrazin-2-yl)phenyl]cyclohexyl]acetic acid | SCHEMBL5532381 | AZD 7687 | GTPL7827 | AKOS030526281 | 6QTJ9P2NYT | AZD 7687 [WHO-DD] | EN300-16131 | NCGC00378858-01 | SCHEMBL2252415 | 1166827-4
Especificaciones y pureza
Moligand™, ≥98%
Mecanismos bioquímicos y fisiológicos

The attenuating effect of AZD7687, the selective DGAT1 inhibitor, on postprandial triacylglycerol (TAG) excursion provides proof of mechanism with respect to gut DGAT1 inhibition. Nausea, vomiting and diarrhoea were reported with increasi

Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
INHIBITOR
Mecanismo de acción
Inhibitor of diacylglycerol O-acyltransferase 1
Pureza
≥98%
Nombres e identificadores
Sonrisas canónicasCC1=C(N=C(C(=N1)C)C(=O)N)C2=CC=C(C=C2)C3CCC(CC3)CC(=O)O
IUPAC Name2-[4-[4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)phenyl]cyclohexyl]acetic acid
InChIKeyYXFNPRHZMOGREC-UHFFFAOYSA-N
INCHI1S/C21H25N3O3/c1-12-19(24-20(21(22)27)13(2)23-12)17-9-7-16(8-10-17)15-5-3-14(4-6-15)11-18(25)26/h7-10,14-15H,3-6,11H2,1-2H3,(H2,22,27)(H,25,26)
Isómeros SMILES CC1=C(N=C(C(=N1)C)C(=O)N)C2=CC=C(C=C2)C3CCC(CC3)CC(=O)O
Peso molecular 367.44
Reaxy-Rn 35562638
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=35562638&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClaseDiazines
SubclassPyrazines
Intermediate Tree Nodes Pyrazine carboxylic acids and derivatives
Direct ParentPyrazinecarboxamides
Alternative Parents 2-heteroaryl carboxamides  Benzene and substituted derivatives  Heteroaromatic compounds  Primary carboxylic acid amides  Monocarboxylic acids and derivatives  Carboxylic acids  Azacyclic compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Pyrazinecarboxamide - 2-heteroaryl carboxamide - Monocyclic benzene moiety - Benzenoid - Heteroaromatic compound - Carboxamide group - Primary carboxylic acid amide - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Azacycle - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Carbonyl group - Hydrocarbon derivative - Aromatic heteromonocyclic compound
DescripciónThis compound belongs to the class of organic compounds known as pyrazinecarboxamides. These are compounds containing a pyrazine ring which bears a carboxamide.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
DGAT1 Tclin Diacylglycerol O-acyltransferase 1 (5 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
SolubilidadDMSO
Peso molecular367.400 g/mol
XLogP33.200
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass367.19 Da
Monoisotopic Mass367.19 Da
Topological Polar Surface Area106.000 Ų
Heavy Atom Count27
Formal Charge0
Complexity525.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Preguntas frecuentes y artículos
Calculadoras de soluciones
Reseñas

Reseñas de cliente

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.