GRADE & PURITY ≥97%

Synonyms

Azide-PEG2-CH2COOH | Azido-PEG2-CH2COOH | 2-[2-(2-Azidoethoxy)ethoxy]acetic acid | N-(2-(2-(2-azidoethoxy)ethoxy))acetic acid | Acetic acid, [2-(2-azidoethoxy)ethoxy]-3,6-Dioxa-8-azidooctanoic acid

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Application

227,228,229

Descripción general

Azido-PEG2-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Azido-PEG2-CH2COOH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Specifications

Sinónimos

Azide-PEG2-CH2COOH | Azido-PEG2-CH2COOH | 2-[2-(2-Azidoethoxy)ethoxy]acetic acid | N-(2-(2-(2-azidoethoxy)ethoxy))acetic acid | Acetic acid, [2-(2-azidoethoxy)ethoxy]-3, 6-Dioxa-8-azidooctanoic acid

Especificaciones y pureza

≥97%

Mecanismos bioquímicos y fisiológicos

Azido-PEG2-CH2COOH is a PEG-based PROTAC linker that is applicable to the synthesis of PROTACs.

Condiciones de almacenamiento de almacenamiento

Protected from light, Store at -20°C, Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥97%

Nombres e identificadores

• Sonrisas canónicas: C(COCCOCC(=O)O)N=[N+]=[N-]
• IUPAC Name: 2-[2-(2-azidoethoxy)ethoxy]acetic acid
• InChIKey: OCIIYNXOTJRSHW-UHFFFAOYSA-N
• INCHI: 1S/C6H11N3O4/c7-9-8-1-2-12-3-4-13-5-6(10)11/h1-5H2,(H,10,11)
• Isómeros SMILES: C(COCCOCC(=O)O)N=[N+]=[N-]
• Peso molecular: 189.17
• Reaxy-Rn: 11079311
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11079311&ln=

Propiedades químicas y físicas

• Solubilidad: Solubility (25°C) In vitro
• Sensibilidad: Moisture sensitive；Light sensitive
• Peso molecular: 189.170 g/mol
• XLogP3: 0.400
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 8
• Exact Mass: 189.075 Da
• Monoisotopic Mass: 189.075 Da
• Topological Polar Surface Area: 70.100 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 190.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1