Azido-PEG3-PFP ester - ≥95% , CAS No.1807530-07-9

CAS: 1807530-07-9 Cat. No.: A595357 Peso molecular: 413.30

GRADE & PURITY ≥95%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Azido-PEG3-PFP ester is a PEG derivative containing azide and PFP ester moities. The azide can participate in copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN to form triazole groups. The PFP ester is amine-reactive and is less susceptible toward hydrolysis compared to NHS ester.

Specifications

Especificaciones y pureza

≥95%

Mecanismos bioquímicos y fisiológicos

N3-PEG3-C2-PFP ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-C2-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition re

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

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Pureza

≥95%

Nombres e identificadores

• Isómeros SMILES: C(COCCOCCOCCN=[N+]=[N-])C(=O)OC1=C(C(=C(C(=C1F)F)F)F)F
• Peso molecular: 413.30

Propiedades químicas y físicas

• Solubilidad: Solubility in DMSO, DCM, DMF
• Peso molecular: 413.300 g/mol
• XLogP3: 2.600
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 14
• Exact Mass: 413.101 Da
• Monoisotopic Mass: 413.101 Da
• Topological Polar Surface Area: 68.400 Ų
• Heavy Atom Count: 28
• Formal Charge: 0
• Complexity: 498.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1