[bAla8]-Neurokinin A(4-10), CAS No.122063-01-8

CAS: 122063-01-8 Cat. No.: B286633 Peso molecular: 780.93 PubChem CID: 9987795

GRADE & PURITY ≥98%

Descripción general

[bAla8]-Neurokinin A(4-10) is a neurokinin 2 (NK2) receptor agonist.
Soluble to 0.67 mg/ml in 30% acetonitrile / sterile water.
 Asp-Ser-Phe-Val-{Bal}-Leu-Met-NH2.

Specifications

Product Name

[bAla8]-Neurokinin A(4-10), CAS No.122063-01-8

Sinónimos

MEN 10210 | [beta-Ala8] Neurokinin A (4-10) | (5S, 8R, 15S, 18R, 21S, 24S)-24-amino-18-benzyl-5-carbamoyl-21-(hydroxymethyl)-8-isobutyl-15-isopropyl-7, 10, 14, 17, 20, 23-hexaoxo-2-thia-6, 9, 13, 16, 19, 22-hexaazahexacosan-26-oic acid

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

NK2receptor agonist (pD2= 6.91). Produces bladder contraction and bronchospasm in guinea pigsin vivo.

Secuencia

DSFVALM(Modifications: Ala-5 = β-Ala, Met-7 = C-terminal amide)

CAS

122063-01-8

Tipo de molécula

Small molecule

Almacenamiento y envío

Condiciones de almacenamiento de almacenamiento

Store at -20°C,Desiccated

Enviado en

Ice chest + Ice pads

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Peptidomimetics
      • Subclass Hybrid peptides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Peptidomimetics
• Subclass: Hybrid peptides
• Intermediate Tree Nodes: Not available
• Direct Parent: Hybrid peptides
• Alternative Parents: Dipeptides Phenylalanine and derivatives Aspartic acid and derivatives Methionine and derivatives Leucine and derivatives Valine and derivatives N-acyl-alpha amino acids and derivatives Alpha amino acid amides Serine and derivatives Beta amino acids and derivatives Amphetamines and derivatives N-acyl amines Secondary carboxylic acid amides Primary carboxylic acid amides Amino acids Sulfenyl compounds Monocarboxylic acids and derivatives Carboxylic acids Dialkylthioethers Carbonyl compounds Primary alcohols Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Hybrid peptide - Alpha-dipeptide - Phenylalanine or derivatives - Methionine or derivatives - Aspartic acid or derivatives - Leucine or derivatives - N-acyl-alpha amino acid or derivatives - Valine or derivatives - Alpha-amino acid amide - Serine or derivatives - Beta amino acid or derivatives - Alpha-amino acid or derivatives - N-substituted-alpha-amino acid - Amphetamine or derivatives - Fatty amide - Fatty acyl - N-acyl-amine - Benzenoid - Monocyclic benzene moiety - Amino acid or derivatives - Amino acid - Carboxamide group - Secondary carboxylic acid amide - Primary carboxylic acid amide - Carboxylic acid - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Thioether - Dialkylthioether - Sulfenyl compound - Alcohol - Primary aliphatic amine - Organonitrogen compound - Organooxygen compound - Organosulfur compound - Carbonyl group - Primary alcohol - Primary amine - Hydrocarbon derivative - Organic oxide - Amine - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic homomonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as hybrid peptides. These are compounds containing at least two different types of amino acids (alpha, beta, gamma, delta) linked to each other through a peptide bond.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mecanismos de acción