10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Protected from light,Argon charged,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
BAN ORL 24 is a nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) antagonist. BAN ORL 24 has antagonistic effect for nociceptin (NOP) receptor with K I value of 0.24 nM in CHO cell. BAN ORL 24 can be used for the research of cancer and analgesic
In Vitro
BAN ORL 24 has antagonist for NOR and MOR (opioid receptor subtype) with IC 50 values of 50 μM and 0.224 μM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
BAN ORL 24 (10 mg/kg; i.v.) attenuates the duration of BPRIM97 thermal antinociception. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: C57BL/6 miceDosage: 10 mg/kg Administration: 10 mg/kg; i.v. Result: Caused inhibition of BPRIM97-induced antinociception at 90-min postinjection. Did not attenuate BPR1M97-induced antinociception in the tail-clip test after 30 min.
IC50& Target:Ki: 0.24 nM (NOP in CHO cell),IC50: 50 μM (NOR),0.224 μM (MOR)
Specifications
Especificaciones y pureza
10mM in DMSO
Mecanismos bioquímicos y fisiológicos
BAN ORL 24 is a nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) antagonist. BAN ORL 24 has antagonistic effect for nociceptin (NOP) receptor with K I value of 0.24 nM in CHO cell. BAN ORL 24 can be used for the research of cancer and analgesic.
Condiciones de almacenamiento de almacenamiento
Protected from light, Argon charged, Store at -80°C
Enviado en
Dry ice packs + Cold packs
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