Information
BAY-474 BAY-474 is an inhibitor of tyrosine-protein kinase c-Met and can act as an epigenetics probe.
Targets
c-Met
| ALogP | 1.845 |
|---|---|
| Recuento HBD | 2 |
| Enlace rotable | 1 |
| Sonrisas canónicas | CC1=C2C=C(C=CC2=NN1)C3C(=C(NC(=C3C#N)C)C)C#N |
|---|---|
| IUPAC Name | 2,6-dimethyl-4-(3-methyl-2H-indazol-5-yl)-1,4-dihydropyridine-3,5-dicarbonitrile |
| InChIKey | QKVFMAAIXZONRN-UHFFFAOYSA-N |
| INCHI | 1S/C17H15N5/c1-9-14(7-18)17(15(8-19)10(2)20-9)12-4-5-16-13(6-12)11(3)21-22-16/h4-6,17,20H,1-3H3,(H,21,22) |
| Isómeros SMILES | CC1=C2C=C(C=CC2=NN1)C3C(=C(NC(=C3C#N)C)C)C#N |
| PubChem CID | 24959105 |
| Peso molecular | 289.33 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Clase | Benzopyrazoles |
| Subclass | Indazoles |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Indazoles |
| Alternative Parents | Dihydropyridines Benzenoids Pyrazoles Heteroaromatic compounds Nitriles Enamines Dialkylamines Azacyclic compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Benzopyrazole - Indazole - Dihydropyridine - Hydropyridine - Benzenoid - Azole - Heteroaromatic compound - Pyrazole - Secondary aliphatic amine - Enamine - Azacycle - Carbonitrile - Nitrile - Hydrocarbon derivative - Organic nitrogen compound - Organonitrogen compound - Cyanide - Amine - Aromatic heteropolycyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as indazoles. These are compounds containing an indazole, which is structurally characterized by a pyrazole fused to a benzene. |
| External Descriptors | Not available |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 H2413004 | Certificate of Analysis | Jun 05, 2026 | B420416 |
| DMSO (mg/ml) Solubilidad máxima | 58 |
|---|---|
| DMSO (mM) Solubilidad máxima | 200.463138976255 |
| Agua (mg/ml) Solubilidad máxima | ＜1 |
| Peso molecular | 289.330 g/mol |
| XLogP3 | 2.300 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 1 |
| Exact Mass | 289.133 Da |
| Monoisotopic Mass | 289.133 Da |
| Topological Polar Surface Area | 88.300 Ų |
| Heavy Atom Count | 22 |
| Formal Charge | 0 |
| Complexity | 602.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
