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≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C,Desiccated Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Belvarafenib TFA (HM95573 TFA) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC 50 s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv 600E and C-RAF respectively.
Appearance:Solid
IC50& Target:IC50: 56 nM(B-RAF), 7 nM(B-RAFv 600E ), 5 nM(C-RAF) .
In Vitro:Belvarafenib (Example 116) is a potent and pan RAF inhibitor with antineoplastic activity. The IC 50 values of Belvarafenib are 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv 600E and C-RAF respectively. It also shows high inhibitory activity for FMS, DDR1 and DD
Biological Activity:Belvarafenib TFA (HM95573 TFA) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC 50 s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv 600E and C-RAF respectively.
| Peso molecular | 592.95 |
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