Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Desiccated,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Bezisterim (HE 3286; NE-3107) is a synthetic derivative of a natural anti-inflammatory steroid, β-AET. Bezisterim is an orally active partial NF-κB inhibitor. HE3286 reduces proinflammatory signals, including IL-6 and matrix metallopeptidase 3. Bezisterim freely penetrates the blood brain barrierin mice. Bezisterim can be used for the research of the ulcerative colitis, arthritis, experimental autoimmune encephalomyelitis. Bezisterim is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
| Isómeros SMILES | C[C@]12CC[C@@H](CC1=C[C@@H]([C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@]4(C#C)O)C)O)O |
|---|---|
| PubChem CID | 16739648 |
| Peso molecular | 330.46 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| 1. Kaili Liu, Jianli Li, Zhiwei Sun, Yuheng Sun, Xuerui Zhang, Yang Sui, Zhongyuan Qu, Xiang Zou. (2025) Chelidonine-induced inhibition of FBP1 disrupts M2 macrophage polarization and attenuates breast cancer. PHYTOMEDICINE, [PMID:41175579] [10.1016/j.phymed.2025.157451] |
| 2. Yin Xuanying, Qiu Jinmei, Cheng Guowang, Wu Jiaxin, Wang Chen, Zheng Chunye, Huang Shuiqing, Chen Tongkai. (2025) Biomimetic nanodelivery system with simultaneous blood–brain barrier-crossing and neuroprotective abilities for anti-parkinsonian therapy. Chinese Medicine, 20 (1): (1-24). [PMID:41204267] [10.1186/s13020-025-01239-2] |
| 3. Zhongyuan Qu, Huimin Li, Fajing Qiang, Kaili Liu, Shuang Wu, Jianli Li, Xiang Zou. (2025) Regulation of inflammation by Chaihu-Shugan-San: Targeting the IL-17/ NF-κB pathway to combat breast cancer-related depression. PHYTOMEDICINE, [PMID:40382939] [10.1016/j.phymed.2025.156836] |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →
