BIO-013077-01 - 10mM in DMSO , CAS No.746667-48-1

CAS: 746667-48-1 Cat. No.: B656271 Fórmula: C₁₇H₁₃N₅ Peso molecular: 287.32 Número EC: 110-524-2 PubChem CID: 10469294

CALIDAD & PUREZA 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

BIO-013077-01 is a pyrazole TGF-β inhibitor.

In Vitro

A wide range of cellular functions such as cell proliferation, differentiation, adhesion, migration, and apoptosis are regulated by TGF-β superfamily members. The TGF-βs include the three major TGF-β isoforms, TGF-β1, TGF-β2, and TGF-β3 which are expressed in mammals. TGF-β transduces signals through a complex of two related but structurally and functionally distinct serine/threonine kinase receptors, termed type 1 and type II. Deregulation of TGF-β signaling has been also implicated in various human diseases including cancer, pancreatic diseases, and hematological malignancies. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Especificaciones

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

BIO-013077-01 is a pyrazole TGF-β inhibitor.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nombres e identificadores

Isómeros SMILES

CC1=NC(=CC=C1)C2=C(C=NN2)C3=CC4=NC=CN=C4C=C3

CAS alternativo

746667-48-1

PubChem CID

10469294

Peso molecular

287.32