Biotin-LC-Kemptide, TFA salt

Cat. No.: B1511692
Disponible para pedir
GRADE & PURITY BioReagent ? BioReagent grade — tested suitable for life-science and molecular-biology use. Use for cell culture, assays, and biochemical work needing biological compatibility. ≥98%(HPLC)
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1mg
B1511692-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
39,90US$
5mg
B1511692-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
119,90US$
25mg
B1511692-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
419,90US$
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Why this grade

BioReagent,≥98%(HPLC) BioReagent for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Protected from light,Store at -20°C,Desiccated,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

  Biotin-LC-Kemptide is a synthetic, biotinylated peptide substrate specifically designed for protein kinase A (PKA) activity assays and related phosphorylation research. It consists of the canonical Kemptide sequence (Leu-Arg-Arg-Ala-Ser-Leu-Gly, LRRASLG) labeled at the N-terminus with a biotin moiety linked via a 6-aminocaproic acid (LC, long chain) spacer, which minimizes steric hindrance and preserves substrate recognition by PKA.
  Full Name: Biotin-LC-Leu-Arg-Arg-Ala-Ser-Leu-Gly (Biotin-LC-LRRASLG)
  Molecular Formula: C₄₈H₈₆N₁₆O₁₂S (free base)
  Molecular Weight: 1111.39 (free base)
Key Features & Applications
1. PKA Substrate Specificity: The central Ser residue serves as the exclusive phosphorylation site for PKA, enabling quantitative measurement of kinase activity through phosphate incorporation or antibody-based detection.
2. Biotin Affinity Tag: The biotin-LC modification allows efficient capture, purification, or immobilization of the phosphorylated peptide via streptavidin/avidin matrices, supporting high-throughput screening and pull-down assays.
3. Research Applications: Widely used in PKA activity quantification, kinase inhibitor screening, phosphorylation kinetics studies, and protein-protein interaction analysis involving PKA signaling pathways.

Specifications

Product Name
Biotin-LC-Kemptide, TFA salt
Sinónimos
Protein kinase A substrate | Biotin-6-aminohexanoic acid-Kemptide | LC-Kemptide (Biotin) Peptide | LC-Kemptide Biotin peptide | LC-Kemptide, Peptide | Biotin-LC-LRRASLG
Grado
BioReagent
Especificaciones y pureza
BioReagent, ≥98%(HPLC)
Peso molecular previsto
1111.39 (free base)
Tipo de molécula
Peptide
Almacenamiento y envío
Condiciones de almacenamiento de almacenamiento
Protected from light,Store at -20°C,Desiccated,Avoid repeated freezing and thawing
Enviado en
Ice chest + Ice pads
Estabilidad y almacenamiento
Store at -20℃ long term. Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle. Store in the dark. Desiccated.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Calculadoras de soluciones
Reseñas

Reseñas de cliente

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Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

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