Biotin-PEG2-azide - ≥98% , CAS No.1910803-72-3

CAS: 1910803-72-3 Cat. No.: B595446 Peso molecular: 400.5

GRADE & PURITY ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Biotin-PEG2-azide is PEG derivative containing a biotin group and an azide group. The azide group can react with either alkyne moiety in Cu(I)-catalyzed Click Chemistry reaction or DBCO moiety in copper-free Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.

Specifications

Especificaciones y pureza

≥98%

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥98%

Nombres e identificadores

• Sonrisas canónicas: C1C2C(C(S1)CCCCC(=O)NCCOCCOCCN=[N+]=[N-])NC(=O)N2
• IUPAC Name: N-[2-[2-(2-azidoethoxy)ethoxy]ethyl]-5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide
• InChIKey: OVEZMVONEJMGLZ-UHFFFAOYSA-N
• INCHI: 1S/C16H28N6O4S/c17-22-19-6-8-26-10-9-25-7-5-18-14(23)4-2-1-3-13-15-12(11-27-13)20-16(24)21-15/h12-13,15H,1-11H2,(H,18,23)(H2,20,21,24)
• Peso molecular: 400.5
• Reaxy-Rn: 50740936
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=50740936&ln=

Propiedades químicas y físicas

• Solubilidad: Solubility in Water, DMSO, DCM, DMF

Referencias

1. Jia Mutian, Wang Yuanyuan, Wang Jie, Qin Danhui, Wang Mengge, Chai Li, Fu Yue, Zhao Chunyuan, Gao Chengjiang, Jia Jihui, Zhao Wei.  (2023)  Myristic acid as a checkpoint to regulate STING-dependent autophagy and interferon responses by promoting N-myristoylation.  Nature Communications,  14  (1): (1-12).  [PMID:36750575] [10.1038/s41467-023-36332-3]