Blebbistatin - Moligand™, 10 mM in DMSO , CAS No.674289-55-5

CAS: 674289-55-5 Cat. No.: B1496650 Peso molecular: 292.34
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1ml
B1496650-1ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
102,90US$
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 7 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor, promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing, and better preserves cell junctional integrity and barrier function. Blebbistatin blocks cell migration .

Specifications

Especificaciones y pureza
Moligand™, 10 mM in DMSO
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
INHIBITOR
Nombres e identificadores
Isómeros SMILES CC1=CC2=C(C=C1)N=C3C(C2=O)(CCN3C4=CC=CC=C4)O
Peso molecular 292.34
Reaxy-Rn 10016269
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=10016269&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Citations of This Product
Referencias
1. Longjie Li, Weiran Qin, Jing Xie.  (2025)  Engineering Patterned Tumor Microtissues in 3D Microwells via Stress Relaxation-Regulated Cell-Matrix Interactions.  Journal of Materials Chemistry B,      [PMID:41003668] [10.1039/D5TB01526J]
2. Chen Li, Zihui Zheng, Xiang Wu, Qiu Xie, Ping Liu, Yunfeng Hu, Mei Chen, Liming Liu, Wangxing Zhao, Linlin Chen, Jun Guo, Ying Song.  (2023)  Stiff matrix induced srGAP2 tension gradients control migration direction in triple-negative breast cancer.  Theranostics,      [PMID:36593959] [10.7150/thno.77313]
3. Yunfeng Hu, Qiu Xie, Shanshan Chen, Wangxing Zhao, Xudong Zhao, Qinli Ruan, Zihui Zheng, Huanhuan Zhao, Tonghui Ma, Jun Guo, Lei Li.  (2022)  Par3 promotes breast cancer invasion and migration through pull tension and protein nanoparticle-induced osmotic pressure.  BIOMEDICINE & PHARMACOTHERAPY,      [PMID:36179489] [10.1016/j.biopha.2022.113739]
4. Siyuan Huang, Qi Su, Xiaoqiang Hou, Kuankuan Han, Shufang Ma, Bingshe Xu, Yingjun Yang.  (2022)  Influence of Colonies’ Morphological Cues on Cellular Uptake Capacity of Nanoparticles.  Frontiers in Bioengineering and Biotechnology,      [PMID:35711638] [10.3389/fbioe.2022.922159]
5. Ying Song, Chen Li, Yahan Fu, Qiu Xie, Jun Guo, Guangming Li, Huiwen Wu.  (2020)  Inward Tension of Talin and Integrin-related Osmotic Pressure are involved Synergetically in the Invasion and Metastasis of Non-small Cell Lung Cancer.  Journal of Cancer,      [PMID:32742451] [10.7150/jca.45494]
6. Yifan Wang, Xiaolong Zhang, Jilai Tian, Jinjun Shan, Yunfeng Hu, Yiqian Zhai, Jun Guo.  (2019)  Talin promotes integrin activation accompanied by generation of tension in talin and an increase in osmotic pressure in neurite outgrowth.  FASEB JOURNAL,  33  (5): (6311-6326).  [PMID:30768370] [10.1096/fj.201801949RR]
7. Ling Zhu, Zihui Zheng, Wang Li, Chenyi Shou, Ying Zhao, Lijun Zhang, Xiaoli Shi, Yunfeng Hu, Huanhuan Zhao, Huiwen Wu, Jun Guo.  (2025)  Osmotic Tension Asymmetry Drives Electrotactic Migration via PDLIM7-Polarized Microfilament Coordination in Breast Cancer Cells.  Advanced Science,      [PMID:41431193] [10.1002/advs.202515246]
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