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· · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items BMS 566419 - ≥98%(HPLC) , CAS No.566161-24-8
Synonyms
Acridone-Based Inhibitor, 4m | UNII-9688E11ZQ0 | N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2-fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide | 9688E11ZQ0 | BDBM19289 | BMS-566419 | Q27271886 | n-[1-[6-(4-ethyl-1-piperazinyl)-3-pyridinyl]-1-
Shipped In
Ice chest + Ice pads
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Why this grade ≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Sinónimos
Acridone-Based Inhibitor, 4m | UNII-9688E11ZQ0 | N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2-fluoro-9-oxo-9, 10-dihydroacridine-3-carboxamide | 9688E11ZQ0 | BDBM19289 | BMS-566419 | Q27271886 | n-[1-[6-(4-ethyl-1-piperazinyl)-3-pyridinyl]-1-
Especificaciones y pureza
≥98%(HPLC)
Mecanismos bioquímicos y fisiológicos
Potent inosine monophosphate dehydrogenase (IMPDH) inhibitor (IC50= 17 nM). Inhibits proliferation of human T-lymphoblasts and PBMCsin vitro. Reduces paw swelling in a rat adjuvant arthritis model. Orally available.
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Nombres e identificadores Sonrisas canónicas CCN1CCN(CC1)C2=NC=C(C=C2)C(C)(C)NC(=O)C3=C(C=C4C(=C3)NC5=CC=CC=C5C4=O)F IUPAC Name N-[2-[6-(4-ethylpiperazin-1-yl)pyridin-3-yl]propan-2-yl]-2-fluoro-9-oxo-10H-acridine-3-carboxamide InChIKey XEVJUIZOZCFECP-UHFFFAOYSA-N INCHI 1S/C28H30FN5O2/c1-4-33-11-13-34(14-12-33)25-10-9-18(17-30-25)28(2,3)32-27(36)20-16-24-21(15-22(20)29)26(35)19-7-5-6-8-23(19)31-24/h5-10,15-17H,4,11-14H2,1-3H3,(H,31,35)(H,32,36) Isómeros SMILES CCN1CCN(CC1)C2=NC=C(C=C2)C(C)(C)NC(=O)C3=C(C=C4C(=C3)NC5=CC=CC=C5C4=O)F Peso molecular 487.57 Reaxy-Rn 11171623 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11171623&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Clase Quinolines and derivatives Subclass Benzoquinolines Intermediate Tree Nodes Acridines Direct Parent Acridones Alternative Parents Quinoline carboxamides Fluoroquinolones N-arylpiperazines Pyridinylpiperazines Haloquinolines Hydroquinolones 2-halobenzoic acids and derivatives Hydroquinolines Dialkylarylamines N-alkylpiperazines Aminopyridines and derivatives Imidolactams Aryl fluorides Heteroaromatic compounds Vinylogous halides Vinylogous amides Amino acids and derivatives Secondary carboxylic acid amides Trialkylamines Azacyclic compounds Organofluorides Organooxygen compounds Hydrocarbon derivatives Organic oxides Molecular Framework Aromatic heteropolycyclic compounds Substituents Acridone - Quinoline-7-carboxamide - Fluoroquinolone - Pyridinylpiperazine - N-arylpiperazine - Haloquinoline - Dihydroquinolone - Dihydroquinoline - 2-halobenzoic acid or derivatives - Halobenzoic acid or derivatives - Dialkylarylamine - Aminopyridine - N-alkylpiperazine - Aryl fluoride - Aryl halide - 1,4-diazinane - Piperazine - Pyridine - Imidolactam - Benzenoid - Heteroaromatic compound - Vinylogous halide - Vinylogous amide - Amino acid or derivatives - Tertiary aliphatic amine - Tertiary amine - Secondary carboxylic acid amide - Carboxamide group - Azacycle - Carboxylic acid derivative - Amine - Hydrocarbon derivative - Organic nitrogen compound - Organohalogen compound - Organic oxygen compound - Organofluoride - Organonitrogen compound - Organooxygen compound - Organic oxide - Aromatic heteropolycyclic compound Descripción This compound belongs to the class of organic compounds known as acridones. These are acridines containing a ketone group attached to the C9 carbon atom of the acridine moiety. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Solubilidad Solvent:1eq. HCl, Max Conc. mg/mL: 24.38, Max Conc. mM: 50; Solvent:DMSO, Max Conc. mg/mL: 48.76, Max Conc. mM: 100 Peso molecular 487.600 g/mol XLogP3 4.000 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 7 Rotatable Bond Count 5 Exact Mass 487.238 Da Monoisotopic Mass 487.238 Da Topological Polar Surface Area 77.600 Ų Heavy Atom Count 36 Formal Charge 0 Complexity 801.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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