BMX-IN-1 - Moligand™, 10 mM in DMSO , CAS No.1431525-23-3

CAS: 1431525-23-3 Cat. No.: B1499255 Peso molecular: 524.59

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys 496 in the BMX ATP binding domain with an IC 50 of 8 nM, also targets the related Bruton’s tyrosine kinase ( BTK ) with an IC 50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk , JAK3 , EGFR , Itk , or Tec activity.

Specifications

Especificaciones y pureza

Moligand™, 10 mM in DMSO

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

INHIBITOR

Nombres e identificadores

• Isómeros SMILES: CC1=C(C=C(C=C1)N2C(=O)C=CC3=CN=C4C=CC(=CC4=C32)C5=CC=C(C=C5)NS(=O)(=O)C)NC(=O)C=C
• Peso molecular: 524.59
• Reaxy-Rn: 24629814
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24629814&ln=