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Bobcat339 hydrochloride - ≥99% , CAS No.2436747-44-1
Disponible para pedir
GRADE & PURITY ≥99%
Storage
Store at 2-8°C,Desiccated
Shipped In
Wet ice
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Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Bobcat339 hydrochloride is a potent and selective cytosine-based inhibitor of TET enzyme , with the IC 50 s of 33 μM and 73 μM for TET1 and TET2 , respectively. Bobcat339 hydrochloride is useful to the field of epigenetics and serves as a starting point for new therapeutics that target DNA methylation and gene transcription
In Vitro
Bobcat339 (10 μM; 24 hours) significantly reduces global 5hmC levels by inhibiting TET enzyme function in HT-22 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:TET1 33 μM (IC 50 ) TET2 73 μM (IC 50 )
Specifications
Especificaciones y pureza
≥99%
Mecanismos bioquímicos y fisiológicos
Bobcat339 hydrochloride is a potent and selective cytosine-based inhibitor of TET enzyme , with the IC 50 s of 33 μM and 73 μM for TET1 and TET2 , respectively. Bobcat339 hydrochloride is useful to the field of epigenetics and serves as a starting point f
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C, Desiccated
Enviado en
Wet ice
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
INHIBITOR
Pureza
≥99%
Nombres e identificadores
| Sonrisas canónicas | C1=CC=C(C=C1)C2=CC(=CC=C2)N3C=C(C(=NC3=O)N)Cl.Cl |
|---|---|
| IUPAC Name | 4-amino-5-chloro-1-(3-phenylphenyl)pyrimidin-2-one;hydrochloride |
| InChIKey | ZOMPKMMOPYMRIB-UHFFFAOYSA-N |
| INCHI | 1S/C16H12ClN3O.ClH/c17-14-10-20(16(21)19-15(14)18)13-8-4-7-12(9-13)11-5-2-1-3-6-11;/h1-10H,(H2,18,19,21);1H |
| PubChem CID | 138319672 |
| Peso molecular | 334.20 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Estructura 3D
Modelo de Estructura Química Interactiva
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
| Solubilidad | DMSO : 130 mg/mL (388.99 mM; Need ultrasonic) H2O : 0.1 mg/mL (0.30 mM; Need ultrasonic) |
|---|
Calculadoras de soluciones
Reseñas
Reseñas de cliente
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