GRADE & PURITY 10mM in DMSO

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

BPR1J-097 Hydrochloride is a novel and potent FLT3 inhibitor with an IC 50 of 11 nM.

IC50& Target:IC50: 11 nM (FLT3)

In Vitro:BPR1J-097 Hydrochloride is a novel and potent FLT3 inhibitor with an IC 50 of 11nM. Phosphorylation of all FLT3-WT, FLT3-IDT, and FLT3-D835Y are inhibited by BPR1J-097 Hydrochloride at a concentration as low as 10 nM. BPR1J-097 Hydrochloride suppresses th

In Vivo:After i.v. administration of mice with BPR1J-097 Hydrochloride at two cycles of 10 or 25mg/kg, a clear dose-dependent anti-tumour effect is observed. Tumours in mice treated with BPR1J-097 Hydrochloride (25mg/kg per day) stop growing. BPR1J-097 Hydrochl

Biological Activity:BPR1J-097 Hydrochloride is a novel and potent FLT3 inhibitor with an IC 50 of 11u2009nM.

Specifications

Especificaciones y pureza

10mM in DMSO

Condiciones de almacenamiento de almacenamiento

Desiccated, Store at -80°C

Enviado en

Dry ice packs + Cold packs

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Tipo de acción

INHIBITOR

Nombres e identificadores

• Peso molecular: 553.08