Calcein Blue - ≥98%(T) , CAS No.54375-47-2

CAS: 54375-47-2 Cat. No.: C153992 Fórmula: C₁₅H₁₅NO₇ Peso molecular: 321.29 Número EC: 259-129-8

GRADE & PURITY ≥98%(T)

Synonyms

2,2'-(((7-hydroxy-4-methyl-2-oxo-2H-chromen-8-yl)methyl)azanediyl)diacetic acid | 4-Methylumbelliferonemethyleneiminodiacetic Acid | 2-{(carboxymethyl)[(7-hydroxy-4-methyl-2-oxochromen-8-yl)methyl]amino}acetic a cid | AKOS015915984 | RJPSHDMGSVVHFA-UHFFFA

Storage

Room temperature

Shipped In

Normal

Descripción general

product description：

Calcein Blue is a cell-permeable dye that stains viable cells. Upon entering the cell, intracellular esterases cleave the acetoxymethyl (AM) ester group, yielding the membrane-impermeable Calcein Blue fluorescent dye. The staining applications of Calcein blue include tumor tissues, mineralized tissues, bone, amino acids, and many more.

application：

Calcein blue has been used fluorescent labeling of the mineralised sections of bone. Calcein blue AM ester hydrolyzed to calcein blue is suitable as a a viability stain, both microscopically, and in fluorescence activated cell sorting systems. It is also used as a merker of living cells like Schwann cells at neuromuscular junctions.

Specifications

Sinónimos

2,2'-(((7-hydroxy-4-methyl-2-oxo-2H-chromen-8-yl)methyl)azanediyl)diacetic acid | 4-Methylumbelliferonemethyleneiminodiacetic Acid | 2-{(carboxymethyl)[(7-hydroxy-4-methyl-2-oxochromen-8-yl)methyl]amino}acetic a cid | AKOS015915984 | RJPSHDMGSVVHFA-UHFFFA

Especificaciones y pureza

≥98%(T)

Condiciones de almacenamiento de almacenamiento

Room temperature

Enviado en

Normal

Pureza

≥98%(T)

Nombres e identificadores

Pubchem Sid

504763817

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504763817

Sonrisas canónicas

CC1=CC(=O)OC2=C1C=CC(=C2CN(CC(=O)O)CC(=O)O)O

IUPAC Name

2-[carboxymethyl-[(7-hydroxy-4-methyl-2-oxochromen-8-yl)methyl]amino]acetic acid

InChIKey

RJPSHDMGSVVHFA-UHFFFAOYSA-N

INCHI

1S/C15H15NO7/c1-8-4-14(22)23-15-9(8)2-3-11(17)10(15)5-16(6-12(18)19)7-13(20)21/h2-4,17H,5-7H2,1H3,(H,18,19)(H,20,21)

Isómeros SMILES

CC1=CC(=O)OC2=C1C=CC(=C2CN(CC(=O)O)CC(=O)O)O

Peso molecular

321.29

Reaxy-Rn

18100934

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=18100934&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Phenylpropanoids and polyketides
    • Clase Coumarins and derivatives
      • Subclass Hydroxycoumarins

• Kingdom: Organic compounds
• Superclass: Phenylpropanoids and polyketides
• Clase: Coumarins and derivatives
• Subclass: Hydroxycoumarins
• Intermediate Tree Nodes: Not available
• Direct Parent: 7-hydroxycoumarins
• Alternative Parents: Alpha amino acids 1-benzopyrans Pyranones and derivatives Aralkylamines 1-hydroxy-2-unsubstituted benzenoids Dicarboxylic acids and derivatives Heteroaromatic compounds Trialkylamines Lactones Amino acids Oxacyclic compounds Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 7-hydroxycoumarin - Alpha-amino acid - Alpha-amino acid or derivatives - Benzopyran - 1-benzopyran - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Pyranone - Aralkylamine - Benzenoid - Dicarboxylic acid or derivatives - Pyran - Heteroaromatic compound - Amino acid or derivatives - Amino acid - Lactone - Tertiary aliphatic amine - Tertiary amine - Oxacycle - Organoheterocyclic compound - Carboxylic acid - Carboxylic acid derivative - Organonitrogen compound - Carbonyl group - Organic oxide - Organooxygen compound - Organic nitrogen compound - Organic oxygen compound - Amine - Hydrocarbon derivative - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as 7-hydroxycoumarins. These are coumarins that contain one or more hydroxyl groups attached to the C7 position the coumarin skeleton.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Peso molecular: 321.280 g/mol
• XLogP3: -1.800
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 6
• Exact Mass: 321.085 Da
• Monoisotopic Mass: 321.085 Da
• Topological Polar Surface Area: 124.000 Ų
• Heavy Atom Count: 23
• Formal Charge: 0
• Complexity: 514.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1