Calpain Inhibitor VI, CAS No.190274-53-4

CAS: 190274-53-4 Cat. No.: C336446 Peso molecular: 372.5
Disponible para pedir
GRADE & PURITY ≥95%
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1mg
C336446-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

119,90US$

147,90US$
Guardar 28,00 US$ (18.93%)
5mg
C336446-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

592,90US$

666,90US$
Guardar 74,00 US$ (11.10%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Calpain Inhibitor VI is a cell permeable peptide aldehyde which functions as a reversible calpain inhibitor. Studies indicate that Calpain Inhibitor VI strongly inhibits cathepsin B and cathepsin L. In addition, Calpain Inhibitor VI reduces nuclear opacity and proteolysis of crystallins and α-spectrin induced by A23187 . Studies suggest that substitution at the P1 position, specially a bulky amino acid residual aldehyde, will increase the potency of the Calpain Inhibitor VI. Furthermore, the S-configuration of Calpain Inhibitor VI is important in the inhibition of cathepsin L.

Specifications

Product Name
Calpain Inhibitor VI, CAS No.190274-53-4
Sinónimos
N-(4-Fluorophenylsulfonyl)-L-Valyl-L-Leucinal | 2-[(4-fluorophenyl)sulfonylamino]-3-methyl-N-(4-methyl-1-oxopentan-2-yl)butanamide | DTXSID80622709 | N~2~-(4-Fluorobenzene-1-sulfonyl)-N-(4-methyl-1-oxopentan-2-yl)valinamide
Especificaciones y pureza
≥95%
Secuencia
4-Fluorophenylsulfonyl-Val-Leu-CHO
Tipo de acción
INHIBITOR
CAS
190274-53-4
Tipo de molécula
Small molecule
Almacenamiento y envío
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
CAPN1 Tchem Calpain-1 catalytic subunit (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Calculadoras de soluciones
Reseñas

Reseñas de cliente

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.