Capromorelin tartrate - ≥95% , CAS No.193273-69-7

CAS: 193273-69-7 Cat. No.: C412217 Peso molecular: 655.7 Número EC: 110-650-8 PubChem CID: 9852610

GRADE & PURITY ≥95%

Synonyms

193273-69-7 (tartrate) | Capromorelin tartrate [USAN] | D03373 | PROPANAMIDE, 2-AMINO-N-(2-(2,3,3A,4,6,7-HEXAHYDRO-2-METHYL-3-OXO-3A-(PHENYLMETHYL)-5H-PYRAZOLO(4,3-C)PYRIDIN-5-YL)-2-OXO-1-((PHENYLMETHOXY)METHYL)ETHYL)-2-METHYL-, (R-(R*,R*))-, (R-(R*,R*))-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Information

Capromorelin tartrate Capromorelin Tartrate (CP 424391-18), a member of the growth hormone secretagogue (GHS) class of drugs, is a ghrelin receptor agonist and a novel therapy for stimulation of appetite in dogs with Ki of 7 nM for hGHS-R1a and EC50 of 3 nM for rat pituicyte.

Targets

rat pituicyte (Cell-free assay); hGHS-R1a (Cell-free assay) 3 nM(EC50); 7 nM(Ki)

Specifications

Sinónimos

193273-69-7 (tartrate) | Capromorelin tartrate [USAN] | D03373 | PROPANAMIDE, 2-AMINO-N-(2-(2, 3, 3A, 4, 6, 7-HEXAHYDRO-2-METHYL-3-OXO-3A-(PHENYLMETHYL)-5H-PYRAZOLO(4, 3-C)PYRIDIN-5-YL)-2-OXO-1-((PHENYLMETHOXY)METHYL)ETHYL)-2-METHYL-, (R-(R*, R*))-, (R-(R*, R*))-

Especificaciones y pureza

≥95%

Mecanismos bioquímicos y fisiológicos

Capromorelin Tartrate (CP 424391-18), a member of the growth hormone secretagogue (GHS) class of drugs, is a ghrelin receptor agonist and a novel therapy for stimulation of appetite in dogs with Ki of 7 nM for hGHS-R1a and EC50 of 3 nM for rat pituicyte.

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥95%

Nombres e identificadores

• Pubchem Sid: 504764976
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504764976
• Sonrisas canónicas: CC(C)(C(=O)NC(COCC1=CC=CC=C1)C(=O)N2CCC3=NN(C(=O)C3(C2)CC4=CC=CC=C4)C)N.C(C(C(=O)O)O)(C(=O)O)O
• IUPAC Name: N-[(2R)-1-[(3aR)-3a-benzyl-2-methyl-3-oxo-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]-1-oxo-3-phenylmethoxypropan-2-yl]-2-amino-2-methylpropanamide;(2R,3R)-2,3-dihydroxybutanedioic acid
• InChIKey: MJGRJCMGMFLOET-MYPSAZMDSA-N
• INCHI: 1S/C28H35N5O4.C4H6O6/c1-27(2,29)25(35)30-22(18-37-17-21-12-8-5-9-13-21)24(34)33-15-14-23-28(19-33,26(36)32(3)31-23)16-20-10-6-4-7-11-20;5-1(3(7)8)2(6)4(9)10/h4-13,22H,14-19,29H2,1-3H3,(H,30,35);1-2,5-6H,(H,7,8)(H,9,10)/t22-,28-;1-,2-/m11/s1
• Isómeros SMILES: CC(C)(C(=O)N[C@H](COCC1=CC=CC=C1)C(=O)N2CCC3=NN(C(=O)[C@@]3(C2)CC4=CC=CC=C4)C)N.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O
• CAS alternativo: 193273-66-4
• PubChem CID: 9852610
• Peso molecular: 655.7

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Peptides
          • Level6 Dipeptides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Peptides
• Direct Parent: Dipeptides
• Alternative Parents: 3-benzylpiperidines N-acyl-alpha amino acids and derivatives Alpha amino acid amides Benzylethers N-acylpiperidines Sugar acids and derivatives Short-chain hydroxy acids and derivatives Beta hydroxy acids and derivatives Alpha hydroxy acids and derivatives Dicarboxylic acids and derivatives Fatty acids and conjugates Pyrazolones Monosaccharides Tertiary carboxylic acid amides Secondary carboxylic acid amides Secondary alcohols 1,2-diols N-alkylated hydrazones Dialkyl ethers Azacyclic compounds Carboxylic acids Carbonyl compounds Hydrocarbon derivatives Monoalkylamines Organic oxides
• Molecular Framework: Not available
• Substituents: Alpha-dipeptide - N-acyl-alpha amino acid or derivatives - 3-benzylpiperidine - Benzylpiperidine - Alpha-amino acid amide - Alpha-amino acid or derivatives - N-acyl-piperidine - Benzylether - Beta-hydroxy acid - Short-chain hydroxy acid - Sugar acid - Dicarboxylic acid or derivatives - Hydroxy acid - Monosaccharide - Alpha-hydroxy acid - Fatty acid - Monocyclic benzene moiety - Piperidine - Pyrazolinone - Benzenoid - Pyrazoline - Tertiary carboxylic acid amide - 1,2-diol - Amino acid or derivatives - Secondary alcohol - Secondary carboxylic acid amide - Carboxamide group - N-alkylated hydrazone - Carboxylic acid - Ether - Azacycle - Dialkyl ether - Organoheterocyclic compound - Organic nitrogen compound - Carbonyl group - Primary aliphatic amine - Organonitrogen compound - Organooxygen compound - Primary amine - Amine - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Alcohol - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Solubility (25°C) In vitro DMSO: 100 mg/mL (152.5 mM); Water: 100 mg/mL (152.5 mM); Ethanol: 100 mg/mL (152.5 mM)
• Peso molecular: 655.700 g/mol
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 12
• Exact Mass: 655.285 Da
• Monoisotopic Mass: 655.285 Da
• Topological Polar Surface Area: 232.000 Ų
• Heavy Atom Count: 47
• Formal Charge: 0
• Complexity: 1010.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3