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CARM1-IN-1 - Moligand™,≥95% , CAS No.1020399-49-8

CAS: 1020399-49-8 Cat. No.: C651239 Peso molecular: 555.26 PubChem CID: 24827559
COA
CARM1-IN-1 - ≥95% CAS No(1020399-49-8) by Aladdin Scientific
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
Synonyms
CARM1 Inhibitor | Coactivator-Associated Arginine Methyltransferase 1 Inhibitor | 1-Benzyl-3,5- bis-(3-bromo-4-hydroxybenzylidene)piperidin-4-one | 3,5- bis(3-Bromo-4-hydroxybenzylidene)-1-benzylpiperidin-4-one | PRMT Inhibitor V | 1-Benzyl-3,5-bis-(3-bro
Storage
Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
★
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1mg
C651239-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
29,90US$
5mg
C651239-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
79,90US$
10mg
C651239-10mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
119,90US$
25mg
C651239-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
249,90US$
50mg
C651239-50mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
399,90US$
100mg
C651239-100mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
639,90US$
Enter a quantity for the sizes you want to add.
Bulk / Custom
♡ Lista de deseos ⇅ Añadir para comparar ⎙ Print page
SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Descripción general Specifications Nombres e identificadores Documentation Advanced Data Taxonomic Classification Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Calculadoras de soluciones Reseñas
🧪

Why this grade

Moligand™,≥95% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

CARM1-IN-1 (compound 7g) is a highly potent and selective inhibitor of CARM1 (IC50=8.6 μM, CARM1/PABP1), with low inhibitory activity against PRMT1 and SET7 (IC50 >667 μM). CARM1-IN-1 inhibits the methylation activity of CARM1 and the methylation levels of different substrates, such as PABP1, CA150, SmB, and H3. CARM1-IN-1 also inhibits the promoter activity of prostate-specific antigen (PSA) without significant cytotoxicity.

Specifications

Sinónimos
CARM1 Inhibitor | Coactivator-Associated Arginine Methyltransferase 1 Inhibitor | 1-Benzyl-3, 5- bis-(3-bromo-4-hydroxybenzylidene)piperidin-4-one | 3, 5- bis(3-Bromo-4-hydroxybenzylidene)-1-benzylpiperidin-4-one | PRMT Inhibitor V | 1-Benzyl-3, 5-bis-(3-bro
Especificaciones y pureza
Moligand™, ≥95%
Condiciones de almacenamiento de almacenamiento
Protected from light, Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
INHIBITOR
Pureza
≥95%
Nombres e identificadores
Sonrisas canónicasC1C(=CC2=CC(=C(C=C2)O)Br)C(=O)C(=CC3=CC(=C(C=C3)O)Br)CN1CC4=CC=CC=C4
IUPAC Name(3E,5E)-1-benzyl-3,5-bis[(3-bromo-4-hydroxyphenyl)methylidene]piperidin-4-one
InChIKeyKNMFTTWVELIVCC-CLVAPQHMSA-N
INCHI1S/C26H21Br2NO3/c27-22-12-18(6-8-24(22)30)10-20-15-29(14-17-4-2-1-3-5-17)16-21(26(20)32)11-19-7-9-25(31)23(28)13-19/h1-13,30-31H,14-16H2/b20-10+,21-11+
Isómeros SMILES C\1N(C/C(=C\C2=CC(=C(C=C2)O)Br)/C(=O)/C1=C/C3=CC(=C(C=C3)O)Br)CC4=CC=CC=C4
PubChem CID 24827559
Peso molecular 555.26

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClasePiperidines
SubclassBenzylpiperidines
Intermediate Tree Nodes Not available
Direct ParentN-benzylpiperidines
Alternative Parents Phenylmethylamines  O-bromophenols  Benzylamines  Piperidinones  Bromobenzenes  Aralkylamines  1-hydroxy-2-unsubstituted benzenoids  Aryl bromides  Trialkylamines  Cyclic ketones  Azacyclic compounds  Organobromides  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents N-benzylpiperidine - 2-bromophenol - 2-halophenol - Phenylmethylamine - Benzylamine - 1-hydroxy-2-unsubstituted benzenoid - Halobenzene - Bromobenzene - Phenol - Piperidinone - Aralkylamine - Aryl bromide - Monocyclic benzene moiety - Aryl halide - Benzenoid - Tertiary amine - Tertiary aliphatic amine - Cyclic ketone - Ketone - Azacycle - Amine - Organohalogen compound - Organobromide - Organonitrogen compound - Carbonyl group - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Aromatic heteromonocyclic compound
DescripciónThis compound belongs to the class of organic compounds known as n-benzylpiperidines. These are heterocyclic Compounds containing a piperidine ring conjugated to a benzyl group through one nitrogen ring atom.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
U-937 (7138 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LNCaP (8286 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SETD7 Tchem Histone-lysine N-methyltransferase SETD7 (390 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PRMT1 Tchem Protein-arginine N-methyltransferase 1 (867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PRMT3 Tchem Protein arginine N-methyltransferase 3 (219 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DOT1L Tchem Histone-lysine N-methyltransferase, H3 lysine-79 specific (648 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Carm1 Histone-arginine methyltransferase CARM1 (53 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rmtA RmtA (95 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
SolubilidadDMSO : ≥ 35 mg/mL (63.03 mM)
Peso molecular555.300 g/mol
XLogP35.800
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass554.987 Da
Monoisotopic Mass552.989 Da
Topological Polar Surface Area60.800 Ų
Heavy Atom Count32
Formal Charge0
Complexity670.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds2
Covalently-Bonded Unit Count1
Calculadoras de soluciones
Reseñas

Reseñas de cliente

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View Moligand™ grade guide →
Bulk & Custom Packaging Need larger quantities or custom specifications? Contact our team for a tailored quote.

View related series

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