CCR6 inhibitor 1 - ≥99% , CAS No.2437547-04-9

CAS: 2437547-04-9 Cat. No.: C650442 Peso molecular: 504.52

GRADE & PURITY ≥99%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

CCR6 inhibitor 1 is a potent and selective CCR6 inhibitor, with IC 50 s of 0.45 and 6 nM for monkey and human CCR6 , much more selective at CCR6 over human CCR1 (IC 50 , > 30000 nM), and CCR7 (IC 50 , 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer

In Vitro

CCR6 inhibitor 1 (Compound 35) inhibits L20-induced human B cell migration. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:Moneky CCR6 0.45 nM (IC 50 ) Human CCR6 6 nM (IC 50 ) Human CCR7 9400 nM (IC 50 )

Specifications

Especificaciones y pureza

≥99%

Mecanismos bioquímicos y fisiológicos

CCR6 inhibitor 1 is a potent and selective CCR6 inhibitor, with IC 50 s of 0.45 and 6 nM for monkey and human CCR6 , much more selective at CCR6 over human CCR1 (IC 50 , > 30000 nM), and CCR7 (IC 50 , 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phospho

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Pureza

≥99%

Nombres e identificadores

• Peso molecular: 504.52

Propiedades químicas y físicas

• Solubilidad: DMSO : ≥ 125 mg/mL (247.76 mM)