Ceftazidima pentahidrato - ≥98% , CAS No.78439-06-2

CAS: 78439-06-2 Cat. No.: C337845 Peso molecular: 636.65 Número EC: 616-626-8

GRADE & PURITY ≥98%

Synonyms

HMS1569B19 | AKOS015962877 | GR20263 | (Z)-(7R)-7-[2-(2-Aminotiazol-4-il)-2-(1-carboxi-1-metiletoxiimino)acetamido]-3-(1-piridinometil)-3-cefem-4-carboxilato pentahidrato | Ceftazidima (pentahidrato) | AC-18971 | CCG-270303 | (6R,7R)-7-[[(2E)-2-(2-A

Storage

Conservar a -20°C

Shipped In

Hielera + almohadillas de hielo

Descripción general

La ceftazidima pentahidrato es un antibiótico de cefalosporina de tercera generación. Las cefalosporinas están compuestas por ácidos 7-aminocefalosporánicos y son de diferentes tamaños en función de los sustituyentes de su cadena lateral. Los estudios demuestran que la Ceftazidima pentahidratada tiene mayor actividad contra las Pseudomonas aeruginosa que contra los cocos grampositivos.

Specifications

Sinónimos

HMS1569B19 | AKOS015962877 | GR20263 | (Z)-(7R)-7-[2-(2-Aminotiazol-4-il)-2-(1-carboxi-1-metiletoxiimino)acetamido]-3-(1-piridinometil)-3-cefem-4-carboxilato pentahidrato | Ceftazidima (pentahidrato) | AC-18971 | CCG-270303 | (6R, 7R)-7-[[(2E)-2-(2-A

Especificaciones y pureza

≥98%

Condiciones de almacenamiento de almacenamiento

Conservar a -20°C

Enviado en

Hielera + almohadillas de hielo

Pureza

≥98%

Nombres e identificadores

• Pubchem Sid: 488195425
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488195425
• Sonrisas canónicas: CC(C)(C(=O)O)ON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C[N+]4=CC=CC=C4)C(=O)[O-].O.O.O.O.O
• IUPAC Name: (6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;pentahydrate
• InChIKey: NMVPEQXCMGEDNH-NLYPMKEPSA-N
• INCHI: 1S/C22H22N6O7S2.5H2O/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27;;;;;/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34);5*1H2/b26-13+;;;;;/t14-,18-;;;;;/m1...../s1
• Isómeros SMILES: CC(C)(C(=O)O)O/N=C(\C1=CSC(=N1)N)/C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C[N+]4=CC=CC=C4)C(=O)[O-].O.O.O.O.O
• Peso molecular: 636.65
• Reaxy-Rn: 25337281
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25337281&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Lactams
      • Subclass Beta lactams
        • Level5 Cephems
          • Level6 Cephalosporins

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Lactams
• Subclass: Beta lactams
• Intermediate Tree Nodes: Cephems
• Direct Parent: Cephalosporins
• Alternative Parents: N-acyl-alpha amino acids and derivatives 2,4-disubstituted thiazoles 1,3-thiazines Pyridinium derivatives 2-amino-1,3-thiazoles Dicarboxylic acids and derivatives Tertiary carboxylic acid amides Heteroaromatic compounds Secondary carboxylic acid amides Amino acids Azetidines Carboxylic acid salts Dialkylthioethers Carboxylic acids Thiohemiaminal derivatives Azacyclic compounds Organopnictogen compounds Carbonyl compounds Primary amines Organic zwitterions Hydrocarbon derivatives Organic salts Organic oxides
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Cephalosporin - N-acyl-alpha amino acid or derivatives - Alpha-amino acid or derivatives - 2,4-disubstituted 1,3-thiazole - Meta-thiazine - Dicarboxylic acid or derivatives - 1,3-thiazol-2-amine - Pyridine - Pyridinium - Azole - Heteroaromatic compound - Tertiary carboxylic acid amide - Thiazole - Amino acid or derivatives - Azetidine - Carboxamide group - Carboxylic acid salt - Amino acid - Secondary carboxylic acid amide - Thioether - Hemithioaminal - Dialkylthioether - Azacycle - Carboxylic acid derivative - Carboxylic acid - Primary amine - Organic nitrogen compound - Amine - Hydrocarbon derivative - Organopnictogen compound - Carbonyl group - Organic oxide - Organic oxygen compound - Organic salt - Organonitrogen compound - Organic zwitterion - Organooxygen compound - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as cephalosporins. These are compounds containing a 1,2-thiazine fused to a 2-azetidinone to for a oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid moiety or a derivative thereof.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Punto de fusión (°C): >1500°C (lit.)(dec.)
• Peso molecular: 636.700 g/mol
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 17
• Rotatable Bond Count: 8
• Exact Mass: 636.152 Da
• Monoisotopic Mass: 636.152 Da
• Topological Polar Surface Area: 250.000 Ų
• Heavy Atom Count: 42
• Formal Charge: 0
• Complexity: 1020.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 1
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 6

XLogP3