Ceftriaxone sodium trihydrate is a third-generation cephalosporin antibiotic.
A potentially useful antibacterial agent for proteomics research.
| Sonrisas canónicas | CN1C(=NC(=O)C(=N1)[O-])SCC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)[O-].CN1C(=NC(=O)C(=N1)[O-])SCC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)[O-].O.O.O.O.O.O.O.[Na+].[Na+].[Na+].[Na+] |
|---|---|
| IUPAC Name | tetrasodium;(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(2-methyl-6-oxido-5-oxo-1,2,4-triazin-3-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;heptahydrate |
| InChIKey | KTAVBOYXMBQFGR-MAODNAKNSA-J |
| INCHI | 1S/2C18H18N8O7S3.4Na.7H2O/c2*1-25-18(22-12(28)13(29)23-25)36-4-6-3-34-15-9(14(30)26(15)10(6)16(31)32)21-11(27)8(24-33-2)7-5-35-17(19)20-7;;;;;;;;;;;/h2*5,9,15H,3-4H2,1-2H3,(H2,19,20)(H,21,27)(H,23,29)(H,31,32);;;;;7*1H2/q;;4*+1;;;;;;;/p-4/b2*24-8-;;;;;;;;;;;/t2*9-,15-;;;;;;;;;;;/m11.........../s1 |
| Isómeros SMILES | CN1N=C(C(=O)N=C1SCC2=C(N3C(=O)[C@H]([C@H]3SC2)NC(=O)/C(=N\OC)/C4=CSC(=N4)N)C(=O)[O-])[O-].CN1N=C(C(=O)N=C1SCC2=C(N3C(=O)[C@H]([C@H]3SC2)NC(=O)/C(=N\OC)/C4=CSC(=N4)N)C(=O)[O-])[O-].O.O.O.O.O.O.O.[Na+].[Na+].[Na+].[Na+] |
| WGK Alemania | 1 |
| RTECS | XI0368800 |
| CAS alternativo | 73384-59-5，74578-69-1 |
| PubChem CID | 11953897 |
| Peso molecular | 661.58 |
| Reaxy-Rn | 9110623 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Clase | Carboxylic acids and derivatives |
| Subclass | Amino acids, peptides, and analogues |
| Intermediate Tree Nodes | Amino acids and derivatives - Alpha amino acids and derivatives |
| Direct Parent | N-acyl-alpha amino acids and derivatives |
| Alternative Parents | Cephems Alkylarylthioethers 1,2,4-triazines 1,3-thiazines Thiazoles Tertiary carboxylic acid amides Heteroaromatic compounds Carboxylic acid salts Azetidines Isothioureas Monocarboxylic acids and derivatives Azacyclic compounds Propargyl-type 1,3-dipolar organic compounds Dialkylthioethers Sulfenyl compounds Carboxylic acids Thiohemiaminal derivatives Carboximidic acids Carbonyl compounds Hydrocarbon derivatives Organic oxides Organic sodium salts Organic zwitterions Organonitrogen compounds |
| Molecular Framework | Not available |
| Substituents | N-acyl-alpha amino acid or derivatives - Cephem - Aryl thioether - Alkylarylthioether - Meta-thiazine - Triazine - 1,2,4-triazine - Thiazole - Tertiary carboxylic acid amide - Azole - Beta-lactam - Heteroaromatic compound - Lactam - Isothiourea - Azetidine - Carboxylic acid salt - Carboxamide group - Carboximidic acid - Carboximidic acid derivative - Azacycle - Organic alkali metal salt - Carboxylic acid - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Dialkylthioether - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Thioether - Hemithioaminal - Sulfenyl compound - Organic salt - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Organosulfur compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organic sodium salt - Organic zwitterion - Carbonyl group - Aromatic heteropolycyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as n-acyl-alpha amino acids and derivatives. These are compounds containing an alpha amino acid (or a derivative thereof) which bears an acyl group at its terminal nitrogen atom. |
| External Descriptors | Not available |
| Sensibilidad | Light sensitive |
|---|---|
| Rotación específica [α] | -160° (C=1,H2O) |
| Punto de fusión (°C) | 236°C |
| 1. Yonghao Zhang, Yating Song, Liu Liu, Jie Zhang, Zhaoyi Zhang, Qian Li, Jing Yang, Wen Li, Lulu Huang, Xue Li, Yulei Zhang, Qiangshun Wu, Xuejie Guo. (2023) Electrochemical treatment of antibiotic wastewater containing ceftriaxone sodium by porous Ti/Magnéli Ti4O7 nanotube arrays. Water Resources and Industry, [PMID:] [10.1016/j.wri.2023.100235] |
| 2. Haoran Chen, Zongping Wang, Yuxin Huang, Junchi Wei, Gang Guo, Lei Miao. (2023) Anaerobic co-metabolic degradation of ceftriaxone sodium: Performance and mechanism. Journal of Cleaner Production, [PMID:] [10.1016/j.jclepro.2023.136388] |
| 3. Zhang Song-Lin, Yu Long, Su Peng-Chen, Ge Hong-Wei, Sun Ming-Tai, Wang Su-Hua. (2022) Microwave synthesis of zinc-trimesic acid metal–organic framework for visual fluorescence detection of tetracyclines. CHEMICAL PAPERS, 76 (8): (4777-4786). [PMID:] [10.1007/s11696-022-02205-0] |
| 4. Jinhui Yang, Xiaogang Luo. (2020) Ag-doped TiO2 immobilized cellulose-derived carbon beads: One-Pot preparation, photocatalytic degradation performance and mechanism of ceftriaxone sodium. APPLIED SURFACE SCIENCE, [PMID:] [10.1016/j.apsusc.2020.148724] |
| 5. Yating Luo, Jinxing Li, Simou Wu, Wen Jia, Zhimo Zhou, Meixun Liu, Fengling Jiang, Ting Huang, Xi Shen, Yun Li, Fang He, Ruyue Cheng. (2024) Oral supplementation with Bifidobacterium infantis and 2′-fucosyllactose revives gut microbiota perturbation and intestinal and immune developmental delay following early-life antibiotic challenge in BALB/c mice. JOURNAL OF DAIRY SCIENCE, [PMID:39477061] [10.3168/jds.2024-24912] |
| 6. Junchi Wei, Haoran Chen, Daotong Zhao, Jinlong Wang, Miao Zhang, Lei Miao. (2026) Enhancing ceftriaxone sodium degradation in anaerobic sludge through co-metabolic sludge addition without supplementary substrates. Journal of Water Process Engineering, [PMID:] [10.1016/j.jwpe.2026.109451] |
| 7. Weihao Zhao, Lin Gao, Yu Wu, Guihua Xiao, Angran Li, Mingrui Wang, Hongyu Liu, Jinyuan Yang, Dongyue Jin, Yuanlong Zhang, Yongyi Yuan, Pu Dai. (2026) The Optically Guided and Pre-assembled Implantation Cranial Window Reveals Cortical Spatial Representations during Navigation. Research, [PMID:41551915] [10.34133/research.1072] |
