Cellhunt Green CMFDA [5-Chloromethylfluorescein Diacetate] - ≥90% , CAS No.136832-63-8

CAS: 136832-63-8 Cat. No.: C131098 Peso molecular: 464.851

GRADE & PURITY ≥90%

Synonyms

J-006921 | SCHEMBL329253 | Cell Tracker Green | Green CMFDA | CellTracker Green | CHEBI:51626 | DTXSID90159970 | HY-126561 | 5-(Chloromethyl)-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl diacetate | AKOS022180944 | Spiro(isobenzofuran-1(3H),9'-(

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Green CMFDA is a fluorescent reagent with high selectivity.
A fluorescent reagent with high selectivity

Specifications

Sinónimos

J-006921 | SCHEMBL329253 | Cell Tracker Green | Green CMFDA | CellTracker Green | CHEBI:51626 | DTXSID90159970 | HY-126561 | 5-(Chloromethyl)-3-oxo-3H-spiro[isobenzofuran-1, 9'-xanthene]-3', 6'-diyl diacetate | AKOS022180944 | Spiro(isobenzofuran-1(3H), 9'-(

Especificaciones y pureza

≥90%

Mecanismos bioquímicos y fisiológicos

Cell-permeable green fluorescent dye. Does not affect cell viability or proliferation. Transforms intracellularly into a cell-impermeant, fluorescent product. Displays fluorescence for at least 72 hours.

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥90%

Nombres e identificadores

• Sonrisas canónicas: CC(=O)OC1=CC2=C(C=C1)C3(C4=C(C=C(C=C4)CCl)C(=O)O3)C5=C(O2)C=C(C=C5)OC(=O)C
• IUPAC Name: [6'-acetyloxy-5-(chloromethyl)-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] acetate
• InChIKey: IPJDHSYCSQAODE-UHFFFAOYSA-N
• INCHI: 1S/C25H17ClO7/c1-13(27)30-16-4-7-20-22(10-16)32-23-11-17(31-14(2)28)5-8-21(23)25(20)19-6-3-15(12-26)9-18(19)24(29)33-25/h3-11H,12H2,1-2H3
• Isómeros SMILES: CC(=O)OC1=CC2=C(C=C1)C3(C4=C(C=C(C=C4)CCl)C(=O)O3)C5=C(O2)C=C(C=C5)OC(=O)C
• Peso molecular: 464.851
• Reaxy-Rn: 10606918
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=10606918&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Benzopyrans
      • Subclass 1-benzopyrans
        • Level5 Dibenzopyrans
          • Level6 Xanthenes

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Benzopyrans
• Subclass: 1-benzopyrans
• Intermediate Tree Nodes: Dibenzopyrans
• Direct Parent: Xanthenes
• Alternative Parents: Diarylethers Phthalides Benzofuranones Tricarboxylic acids and derivatives Isobenzofurans Benzenoids Lactones Carboxylic acid esters Oxacyclic compounds Organochlorides Organic oxides Hydrocarbon derivatives Carbonyl compounds Alkyl chlorides
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Xanthene - Diaryl ether - Benzofuranone - Isobenzofuranone - Phthalide - Isocoumaran - Isobenzofuran - Tricarboxylic acid or derivatives - Benzenoid - Carboxylic acid ester - Lactone - Carboxylic acid derivative - Oxacycle - Ether - Alkyl chloride - Organohalogen compound - Organochloride - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Carbonyl group - Organic oxygen compound - Alkyl halide - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as xanthenes. These are polycyclic aromatic compounds containing a xanthene moiety, which consists of two benzene rings joined to each other by a pyran ring.
• External Descriptors: acetate ester

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

GSTP1 Tchem Glutathione S-transferase P (1 Activities)

Discover Target: GSTP1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mecanismos de acción

Propiedades químicas y físicas

• Sensibilidad: Moisture sensitive,light sensitive
• Peso molecular: 464.800 g/mol
• XLogP3: 4.000
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 5
• Exact Mass: 464.066 Da
• Monoisotopic Mass: 464.066 Da
• Topological Polar Surface Area: 88.100 Ų
• Heavy Atom Count: 33
• Formal Charge: 0
• Complexity: 760.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Sujuan Yan, Meiling Wan, Weili Liao, Zhenning Dai, Guoguang Chen, Hai Li, Huaxiong Cai, Hongwu Zhang, Wenxu Zheng, Ke Ding, Wuyi Zhou.  (2023)  Alternative Polyurethane/Gutta-Percha/ZnO Biocomposite for Root Canal Therapy Based on an Efficient Melt Extrusion Additive Manufacturing Strategy.  ACS Applied Polymer Materials,      [PMID:] [10.1021/acsapm.3c00323]

2. Qiyi Yi, Youguang Pu, Fengmei Chao, Po Bian, Lei Lv.  (2022)  ACAP1 Deficiency Predicts Inferior Immunotherapy Response in Solid Tumors.  Cancers,  14  (23): (5951).  [PMID:36497434] [10.3390/cancers14235951]

3. Xueni Sun, Jing Xia, Haiyang Jiang, Ting Duan, Chunli Zhang, Qinyi Li, Zuyi Yang, Ruonan Zhang, Xia Ding, Xidong Gu, Xiaohong Xie, Tian Xie, Xinbing Sui.  (2025)  Single-cell and spatial transcriptome profiling identifies cellular heterogeneity and immunosuppressive tumor microenvironment in inflammatory breast cancer.  Journal of Advanced Research,      [PMID:40460936] [10.1016/j.jare.2025.05.061]