Ceramide (Brain, Porcine) - ≥99% , CAS No.497156-25-9

CAS: 497156-25-9 Cat. No.: C130555 Peso molecular: 565.954 PubChem CID: 5283565

GRADE & PURITY ≥99%

Synonyms

Ceramide (Brain) | C18 Ceramide | N-octadecanoyl-D-erythro-sphingosine | N-(octadecanoyl)-sphing-4-enine

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Ceramides comprise sphingoid base attached to fatty acyl chain by an amide bond. They vary in length, saturation and hydroxylation of the fatty acid chain and sphingoid base. Ceramides are synthesized by sphingomyelinase in salvage and de novo synthesis pathway. In brain, ceramide synthases mediate the synthesis of ceramides

Ceramide (Brain) has been used as a lipid standard

· in ultra performance liquid chromatography-electrospray ionization-quadrupole time-of-flight mass spectrometry (UPLC-ESI-Q-TOF-MS)

· in liquid chromatography with a hydrophilic interaction column

· in liposome preparation to test it effect on human α-synuclein aggregation

Specifications

Sinónimos

Ceramide (Brain) | C18 Ceramide | N-octadecanoyl-D-erythro-sphingosine | N-(octadecanoyl)-sphing-4-enine

Especificaciones y pureza

≥99%

Mecanismos bioquímicos y fisiológicos

Ceramides are signalling molecules which play a key role in cellular events. Ceramides promote β-amyloid synthesis and induce neuronal death. Ceramide levels are associated with pathogenesis of many disease states. Impairment of ceramide metabolism is imp

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥99%

Nombres e identificadores

• Isómeros SMILES: CCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@@H](/C=C/CCCCCCCCCCCCC)O
• PubChem CID: 5283565
• Peso molecular: 565.954

Propiedades químicas y físicas

• Peso molecular: 566.000 g/mol
• XLogP3: 13.900
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 32
• Exact Mass: 565.543 Da
• Monoisotopic Mass: 565.543 Da
• Topological Polar Surface Area: 69.600 Ų
• Heavy Atom Count: 40
• Formal Charge: 0
• Complexity: 536.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 1
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 1