CFL-137 - Moligand™, 10 mM in DMSO , CAS No.708-06-5

CAS: 708-06-5 Cat. No.: C1500591 Peso molecular: 172.18 Beilstein Registry Number: 742777 Número EC: 211-902-0
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Argon charged,Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1ml
C1500591-1ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
35,90US$
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Argon charged,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 30 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

CFL-137 is a potent KRas G12C inhibitor. CFL-137 shows an antiproliferative effect. CFL-137 shows anticancer activity. CFL-137 has the potential for the research of lung cancer.

Specifications

Especificaciones y pureza
Moligand™, 10 mM in DMSO
Condiciones de almacenamiento de almacenamiento
Argon charged, Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
INHIBITOR
Nombres e identificadores
Isómeros SMILES C1=CC=C2C(=C1)C=CC(=C2C=O)O
WGK Alemania 2
RTECS QJ0300000
Número ONU 3077
Grupo de embalaje III
Peso molecular 172.18
Beilstein 742777
Reaxy-Rn 742777
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=742777&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
Punto de ebullición (°C)192 °C/27 mmHg
Punto de fusión (°C)81°C
Citations of This Product
Referencias
1. Zhenrong Liu, Zhe Zong, Xiaoxin Li, Shaoping Sun.  (2025)  Smart Polymeric Micelles with Aggregation-Induced Emission and pH-Responsive Fluorescence Color Change Behavior for Bioimaging and Cancer Therapy.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  26  (14): (6654).  [PMID:40724905] [10.3390/ijms26146654]
2. Huajiang Hu, Jiurong Li, Xiao Gong.  (2023)  Hour-Level Persistent Multicolor Phosphorescence Enabled by Carbon Dot-Based Nanocomposites Through a Multi-Confinement-Based Approach.  Small,      [PMID:38126697] [10.1002/smll.202308457]
3. Yiran Che, Jingying Yang, Zhenming Dong, Jianhua Wang, Xiaoqing Yan, Yu Wang, Shaomin Shuang.  (2023)  A sensitive “turn-on” Schiff-base fluorescent probe for the selective detection of Fe3+ and bio-imaging.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:38134651] [10.1016/j.saa.2023.123799]
4. Brian Musikavanhu, Zeping Huang, Quanhong Ma, Yongdi Liang, Zhaoli Xue, Lei Feng, Long Zhao.  (2023)  A pyridine modified naphthol hydrazone Schiff base chemosensor for Al3+ via intramolecular charge transfer process.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:37290147] [10.1016/j.saa.2023.122961]
5. Brian Musikavanhu, Dongwei Zhu, Mengran Tang, Zhaoli Xue, Shengjun Wang, Long Zhao.  (2022)  A naphthol hydrazone Schiff base bearing benzothiadiazole unit for fluorescent detection of Fe3+ in PC3 cells.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:36542920] [10.1016/j.saa.2022.122242]
6. Jing Ying Yang, Wen Ying Gao, Jian Hua Wang, Zhen Ming Dong, Yu Wang, Shao Min Shuang.  (2022)  A new NBD-based probe for specific colorimetric and turn-on fluorescence sensing of Cu2+ and bio-imaging applications.  JOURNAL OF LUMINESCENCE,      [PMID:] [10.1016/j.jlumin.2022.119549]
7. Zhuye Shang, Li Shu, Jianhua Liu, Qingtao Meng, Yue Wang, Jianguo Sun, Run Zhang, Zhiqiang Zhang.  (2022)  Triphenylamine-embedded copper(II) complex as a “turn-on” fluorescent probe for the detection of nitric oxide in living animals.  Analytical Methods,  14  (44): (4537-4544).  [PMID:36314283] [10.1039/D2AY01629J]
8. Brian Musikavanhu, Yujie Zhang, Dongwei Zhu, Zhaoli Xue, Rui Yuan, Shengjun Wang, Long Zhao.  (2022)  Turn-off detection of Cr(III) with chelation enhanced fluorescence quenching effect by a naphthyl hydrazone Shiff base chemosensor.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:35816866] [10.1016/j.saa.2022.121599]
9. Kun WANG, Er-Fei DONG, Min FANG, Ting CHEN, Wei-Ju ZHU, Cun LI.  (2022)  Construction of ratio fluorescence sensor based on CdTe quantum dots and benzocoumarin-3-carboxylic acid for Hg2+ detection.  CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,      [PMID:] [10.1016/j.cjac.2022.100070]
10. Jianping Ye, Qing Zhou, Zhihong Yan, Kang Li.  (2021)  Preparation of multicolor luminescence Schiff-base compound based on solvent control and its application in the detection of pentachloronitrobenzene.  ANALYTICA CHIMICA ACTA,      [PMID:34482876] [10.1016/j.aca.2021.338794]
11. Yingpeng Huo, Jiwen Hu, Yuanyuan Tu, Zhenzhu Huang, Shudong Lin, Xiaojiong Luo, Chao Feng.  (2021)  Efficient magnetically separable heterogeneous platinum catalyst bearing imidazolyl schiff base ligands for hydrosilylation.  JOURNAL OF ORGANOMETALLIC CHEMISTRY,      [PMID:] [10.1016/j.jorganchem.2021.121714]
12. Pengli Guan, Yaoming Liu, Binsheng Yang, Yanbo Wu, Jie Chai, Guangming Wen, Bin Liu.  (2020)  Fluorometric probe for the lipase level: Design, mechanism and biological imaging application.  TALANTA,      [PMID:33592703] [10.1016/j.talanta.2020.121948]
13. Mengya Lv, Yanhao Zhang, Jiayi Fan, Yanyun Yang, Sheng Chen, Gaolin Liang, Shusheng Zhang.  (2020)  A near-infrared fluorescent probe for ratiometric sensing of SO2 in cells and zebrafish.  ANALYST,  145  (24): (7985-7992).  [PMID:33048074] [10.1039/D0AN01468K]
14. Yue Wang, Huan Feng, Haibo Li, Xinyi Yang, Hongmin Jia, Wenjun Kang, Qingtao Meng, Zhiqiang Zhang, Run Zhang.  (2020)  A Copper (II) Ensemble-Based Fluorescence Chemosensor and Its Application in the ‘Naked–Eye’ Detection of Biothiols in Human Urine.  SENSORS,  20  (5): (1331).  [PMID:32121408] [10.3390/s20051331]
15. Chang Jian, Zhang Shu-Zhen, Wu Ya, Zhang Hong-Jia, Sun Yin-Xia.  (2020)  Three supramolecular trinuclear nickel(II) complexes based on Salamo-type chelating ligand: syntheses, crystal structures, solvent effect, Hirshfeld surface analysis and DFT calculation.  TRANSITION METAL CHEMISTRY,  45  (4): (279-293).  [PMID:] [10.1007/s11243-020-00379-8]
16. Zheng Li, Fucai Dai, Jing Wang, Shujun Wang, Liwei Xiao, Lele Li.  (2019)  A selective turn-on fluorescent probe for Al3+ based-on a diacylhydrazone deritive in aqueous medium and its cell imaging.  SYNTHETIC METALS,      [PMID:] [10.1016/j.synthmet.2019.116234]
17. Yingpeng Huo, Jiwen Hu, Shudong Lin, Xingming Ju, Yanlong Wei, Zhenzhu Huang, Yangfei Hu, Yuanyuan Tu.  (2019)  Platinum(II) complexes bearing bulky Schiff base ligands anchored onto mesoporous SBA-15 supports as efficient catalysts for hydrosilylation.  APPLIED ORGANOMETALLIC CHEMISTRY,  33  (6): (e4874).  [PMID:] [10.1002/aoc.4874]
18. Yue Wang, Qingtao Meng, Qian Han, Guangjie He, Yaoyun Hu, Huan Feng, Hongmin Jia, Run Zhang, Zhiqiang Zhang.  (2018)  Selective and sensitive detection of cysteine in water and live cells using a coumarin–Cu2+ fluorescent ensemble.  NEW JOURNAL OF CHEMISTRY,  42  (19): (15839-15846).  [PMID:] [10.1039/C8NJ03809K]
19. Xiu-Mei Zhang, Jie Tang, Li-Na Wang, Di Yao, Qing Yu, Fu-Ping Huang, He-Dong Bian.  (2017)  Superoxide dismutase activity studies of Mn(III)/Co(III)/Fe(III) complexes with Schiff base ligands.  POLYHEDRON,      [PMID:] [10.1016/j.poly.2017.05.026]
20. Peng Li, Mao-Fei Niu, Mei-Ju Niu, Min Hong.  (2014)  Effect of Structure and Composition of Copper and Cobalt Complexes with Schiff Base Ligands on their DNA/Protein Interaction and Cytotoxicity.  ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE,  640  (11): (2238-2246).  [PMID:] [10.1002/zaac.201400051]
21. Wei Lu, Jinting Zhou, Keyuan Liu, Dan Chen, Liming Jiang, Zhiquan Shen.  (2013)  A polymeric film probe with a turn-on fluorescence response to hydrogen sulfate ions in aqueous media.  Journal of Materials Chemistry B,  (38): (5014-5020).  [PMID:32261091] [10.1039/C3TB20731E]
22. Dan Chen, Wei Lu, Ganhong Du, Liming Jiang, Jun Ling, Zhiquan Shen.  (2012)  A chiral polymer-based turn-on fluorescent sensor for specific recognition of hydrogen sulfate.  JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY,  50  (20): (4191-4197).  [PMID:] [10.1002/pola.26230]
23. Wei Lu, Dan Chen, Han Jiang, Liming Jiang, Zhiquan Shen.  (2011)  Polymer-based fluoride-selective chemosensor: Synthesis, sensing property, and its use for the design of molecular-scale logic devices.  JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY,  50  (3): (590-598).  [PMID:] [10.1002/pola.25068]
24. Chen Zhao, Hongmei Xu, Xiaoran Zhang, Yating Meng, Shaomin Shuang, Chuan Dong.  (2024)  Anthraquinone-metal complex fluorescence sensing platform for monitoring PPi mediated by Al3+ and bioimaging.  JOURNAL OF MOLECULAR STRUCTURE,      [PMID:] [10.1016/j.molstruc.2024.138022]
25. Brian Musikavanhu, Tingting Pan, Quanhong Ma, Yongdi Liang, Zhaoli Xue, Lei Feng, Long Zhao.  (2024)  Dual detection of Hg2+ and Pb2+ by a coumarin-functionalized Schiff base in environmental and biosystems.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:38447440] [10.1016/j.saa.2024.124101]
26. Lijun Jin, Lixia Jin, Haiyang Liu, Zhe Wang, yuguang Lv.  (2024)  Study on the Properties of rhodamine B fluorescent probe Y2ST.  JOURNAL OF THE INDIAN CHEMICAL SOCIETY,      [PMID:] [10.1016/j.jics.2024.101420]
27. Guan-Qi Zheng, Jia-Ning Wu, Lin Zhang, Qin Zhang, Lin Chen, Xiu-Li Wang, Hai-Bo Zhao, Bo-Wen Liu, Yu-Zhong Wang.  (2024)  Tailoring cross-linking temperature via hydrogen bonding and steric hindrance towards high-performance fire-Safe Polymer.  POLYMER,      [PMID:] [10.1016/j.polymer.2024.126908]
28. Kangming Xiong, Caixia Yin, Yongkang Yue, Fangjun Huo.  (2019)  A near-infrared ratiometric fluorescence probe base on spiropyran derivative for pH and its application in living cells.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:31306961] [10.1016/j.saa.2019.117350]
29. Minghe Li, Shuyu Zhang, Lu Zhang, Hong Zhong, Chenyu Wang, Chen Wang, Ruirui Feng, Yanni Sun, Yun Ai, Ning Zhang.  (2026)  A Novel Fluorescent Probe for the Determination of Aluminum Ions in Aqueous Samples.  Applied Sciences-Basel,  16  (6):   [PMID:] [10.3390/app16062970]
30. Qian Sun, Lu Ren, Shuangbao Li, Zian Wang, Jing Liu, Zhaoyun Yang, Dawei Zhang.  (2026)  A Turn-On Fluorescent Chemical Sensor Based on Benzo[f]Chromen Structure for Cu2+-Sensitive Detection as Well as Applications.  LUMINESCENCE,  41  (3): (e70466).  [PMID:] [10.1002/bio.70466]
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