≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Chloromethyltrimethoxysilane (CMTMS) is a trialkoxysilane with chloromethyl as the organofunctional group having hydrophobic characteristics. Chloromethyl is the electron withdrawing group that improves the mechanical properties of the molecule. CMTMS is mainly utilized as a silane based precursor material for the preparation of surface enhancement based coatings and other silane based products.
application：
Chloromethyltrimethoxysilane may be used in the preparation of 1-methyl-1H-benzimidazole (MBI)-modified nanoparticles.{33} Mesoporous monolithic silica gels can also be prepared from Chloromethyltrimethoxysilane. {34}
CMTMS and its colloidal solution can be used in the development of aerogels. It can also be used in surface modification of silica nanoparticle for the fabrication of in vitro anticancer drug release system.
| Sonrisas canónicas | CO[Si](CCl)(OC)OC |
|---|---|
| IUPAC Name | chloromethyl(trimethoxy)silane |
| InChIKey | FPOSCXQHGOVVPD-UHFFFAOYSA-N |
| INCHI | 1S/C4H11ClO3Si/c1-6-9(4-5,7-2)8-3/h4H2,1-3H3 |
| Isómeros SMILES | CO[Si](CCl)(OC)OC |
| RTECS | VV2625000 |
| Número ONU | 1993 |
| Grupo de embalaje | II |
| Peso molecular | 170.66 |
| Reaxy-Rn | 1071363 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1071363&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organometallic compounds |
| Clase | Organometalloid compounds |
| Subclass | Organosilicon compounds |
| Intermediate Tree Nodes | Alkoxysilanes |
| Direct Parent | Trialkoxysilanes |
| Alternative Parents | Silyl ethers Organoheterosilanes Organic metalloid salts Organooxygen compounds Organochlorides Hydrocarbon derivatives Alkyl chlorides |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Trialkoxysilane - Silyl ether - Organoheterosilane - Organic metalloid salt - Organic oxygen compound - Hydrocarbon derivative - Organic salt - Organooxygen compound - Organochloride - Organohalogen compound - Alkyl halide - Alkyl chloride - Aliphatic acyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as trialkoxysilanes. These are organosilicon compounds with the general formula RO[Si](R')(OR'')OR''' (R-R''' = aliphatic organyl group). |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 C2609408 | Certificate of Analysis | Feb 27, 2026 | C153550 |
| C2609409 | Certificate of Analysis | Feb 27, 2026 | C153550 |
| C2609429 | Certificate of Analysis | Feb 27, 2026 | C153550 |
| C2609659 | Certificate of Analysis | Feb 27, 2026 | C153550 |
| B2223136 | Certificate of Analysis | Dec 09, 2025 | C153550 |
| G1721021 | Certificate of Analysis | Jan 22, 2025 | C153550 |
| F2419210 | Certificate of Analysis | Jun 27, 2024 | C153550 |
| F2419227 | Certificate of Analysis | Jun 27, 2024 | C153550 |
| F2419228 | Certificate of Analysis | Jun 27, 2024 | C153550 |
| G2521144 | Certificate of Analysis | Jun 26, 2024 | C153550 |
| G2521146 | Certificate of Analysis | Jun 26, 2024 | C153550 |
| G2521147 | Certificate of Analysis | Jun 26, 2024 | C153550 |
| G2521148 | Certificate of Analysis | Jun 26, 2024 | C153550 |
| G2521149 | Certificate of Analysis | Jun 26, 2024 | C153550 |
| C1907008 | Certificate of Analysis | Dec 13, 2022 | C153550 |
| J2213275 | Certificate of Analysis | Aug 09, 2022 | C153550 |
| J2213276 | Certificate of Analysis | Aug 09, 2022 | C153550 |
| J2213279 | Certificate of Analysis | Aug 09, 2022 | C153550 |
| Sensibilidad | Moisture Sensitive |
|---|---|
| Índice de refracción | 1.41 |
| Punto de inflamación (°F) | 26.6 °F |
| Punto de inflamación (°C) | -3°C(lit.) |
| Punto de ebullición (°C) | 151 °C |
| Peso molecular | 170.660 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 4 |
| Exact Mass | 170.017 Da |
| Monoisotopic Mass | 170.017 Da |
| Topological Polar Surface Area | 27.700 Ų |
| Heavy Atom Count | 9 |
| Formal Charge | 0 |
| Complexity | 67.900 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Xiaoliang Li, Jie Cheng, Yanxiang Liu, Shoutao Gong, Gaohong He, Lingdong Li, Shanshan Li, Fengxiang Zhang. (2017) Improved conductivity and stability of anion exchange membrane modified with bi-phenylguanidinium bridged silsesquioxane. INTERNATIONAL JOURNAL OF HYDROGEN ENERGY, [PMID:] [10.1016/j.ijhydene.2017.07.081] |
| 2. Xin Wang, Lihong He, Jianrong Huang, Nanjing Zhong. (2020) Immobilization of lipases onto the halogen & haloalkanes modified SBA-15: Enzymatic activity and glycerolysis performance study. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:33345972] [10.1016/j.ijbiomac.2020.12.111] |
