α-Colestano - ≥97%(GC) , CAS No.481-21-0

CAS: 481-21-0 Cat. No.: C133856 Peso molecular: 372.67 Beilstein Registry Number: 2051806 Número EC: 207-562-8

GRADE & PURITY ≥97%(GC)

Synonyms

Colestano | 5-alfa-Colestano | 5-alfa-Colestano | 28,29,30-Trinorlanostano | .alfa.-Colestano | alfa-Colestano | U260HWN305 | Colestano, (5.alpha.)- | (5alpha)-Colestano | CHEBI:35515 | Colestano (VAN) | 5a-CHOLESTANO

Storage

Room temperature

Shipped In

Normal

Descripción general

el 5α-colestano es un reactivo bioquímico que puede utilizarse como material biológico o compuesto orgánico para la investigación relacionada con las ciencias de la vida.

Propósito

el 5-α-colestano se ha utilizado
como patrón interno en cromatografía en fase gaseosa (GC) y cromatografía líquida de alta resolución (HPLC) para cuantificar el colesterol en productos cárnicos para un estudio comparativo
para cuantificar los compuestos activos de los aceites mediante un cromatógrafo de gases acoplado a un espectrómetro de masas
como patrón de referencia en análisis por CG para cuantificar el contenido de esteroles en los insaponificables obtenidos a partir de lípidos de avena y diferentes patrones de esteroles como fucosterol, sitosterol, campesterol y estigmasterol

Specifications

Sinónimos

Colestano | 5-alfa-Colestano | 5-alfa-Colestano | 28, 29, 30-Trinorlanostano | .alfa.-Colestano | alfa-Colestano | U260HWN305 | Colestano, (5.alpha.)- | (5alpha)-Colestano | CHEBI:35515 | Colestano (VAN) | 5a-CHOLESTANO

Especificaciones y pureza

≥97%(GC)

Mecanismos bioquímicos y fisiológicos

el 5α-colestano es un esterol producido endógenamente a partir del colesterol y se ha aislado de las heces humanas. Se deriva del colesterol por la acción de microorganismos intestinales.Derivados de 5α-colestano en las plantas se llaman Brassinosteroids

Condiciones de almacenamiento de almacenamiento

Room temperature

Enviado en

Normal

Pureza

≥97%(GC)

Nombres e identificadores

• Pubchem Sid: 488192214
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488192214
• Sonrisas canónicas: CC(C)CCCC(C)C1CCC2C1(CCC3C2CCC4C3(CCCC4)C)C
• IUPAC Name: (5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene
• InChIKey: XIIAYQZJNBULGD-XWLABEFZSA-N
• INCHI: 1S/C27H48/c1-19(2)9-8-10-20(3)23-14-15-24-22-13-12-21-11-6-7-17-26(21,4)25(22)16-18-27(23,24)5/h19-25H,6-18H2,1-5H3/t20-,21-,22+,23-,24+,25+,26+,27-/m1/s1
• Isómeros SMILES: C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CCCC4)C)C
• WGK Alemania: 3
• Peso molecular: 372.67
• Beilstein: 2051806
• Reaxy-Rn: 1912740
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1912740&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Clase Steroids and steroid derivatives
      • Subclass Cholestane steroids

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Clase: Steroids and steroid derivatives
• Subclass: Cholestane steroids
• Intermediate Tree Nodes: Not available
• Direct Parent: Cholestane steroids
• Alternative Parents: Polycyclic hydrocarbons Saturated hydrocarbons
• Molecular Framework: Aliphatic homopolycyclic compounds
• Substituents: Cholestane-skeleton - Polycyclic hydrocarbon - Saturated hydrocarbon - Hydrocarbon - Aliphatic homopolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as cholestane steroids. These are steroids with a structure containing the 27-carbon cholestane skeleton.
• External Descriptors: cholestane

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

Discover Target: SLCO1B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Punto de fusión (°C): 80-82°C
• Peso molecular: 372.700 g/mol
• XLogP3: 11.100
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 5
• Exact Mass: 372.376 Da
• Monoisotopic Mass: 372.376 Da
• Topological Polar Surface Area: 0.000 Ų
• Heavy Atom Count: 27
• Formal Charge: 0
• Complexity: 506.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 8
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Wei Lu, Mengping Wang, Jiafeng Chen, Jinmei Wang.  (2023)  Subcritical water-treated soy protein-gum Arabic core-shell nanoparticles as phytosterol carriers.  INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY,  58  (12): (6496-6506).  [PMID:] [10.1111/ijfs.16763]

2. Anning Liu, Huijuan Jing, Xiaojing Du, Chaoyang Ma, Hongxin Wang.  (2022)  Efficient Ultrasonic-assisted Aqueous Enzymatic Method for Pecan Nut Kernel Oil Extraction with Quality Analysis.  Journal of Oleo Science,      [PMID:36464287] [10.5650/jos.ess22119]

3. Pan Gao, Yunpeng Ding, Zhe Chen, Zhangtao Zhou, Wu Zhong, Chuanrong Hu, Dongping He, Xingguo Wang.  (2022)  Characteristics and Antioxidant Activity of Walnut Oil Using Various Pretreatment and Processing Technologies.  Foods,  11  (12): (1698).  [PMID:35741896] [10.3390/foods11121698]

4. Sheng Zhou, Yuxiu Wen, Yiting Duan, Qi Li, Yuan Gao, Xiuzhu Yu.  (2021)  Functional Properties and Composition of New “Nut” Oil Obtained from Xanthium sibiricum Seeds.  EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY,  124  (4): (2100135).  [PMID:] [10.1002/ejlt.202100135]

5. Wenjiang Dong, Qiyu Chen, Changqing Wei, Rongsuo Hu, Yuzhou Long, Ying Zong, Zhong Chu.  (2021)  Comparison of the effect of extraction methods on the quality of green coffee oil from Arabica coffee beans: Lipid yield, fatty acid composition, bioactive components, and antioxidant activity.  ULTRASONICS SONOCHEMISTRY,      [PMID:33965776] [10.1016/j.ultsonch.2021.105578]

6. Qingqing Li, Yong Zhu, Likang Qin.  (2024)  Comparative Study of Camellia oleifera Seed Oil on Chemical Constituents, Antioxidant Activities and Physicochemical Characteristics from Southern China.  Journal of Oleo Science,      [PMID:38945923] [10.5650/jos.ess23228]