Solución de hidróxido de colina - 44 wt. % en H2O , CAS No.123-41-1

CAS: 123-41-1 Cat. No.: C166651 Peso molecular: 121.18 Número EC: 204-625-1

GRADE & PURITY 44 wt. % in H2O

Synonyms

(.BETA.-HYDROXYETHYL)TRIMETHYLAMMONIUM HYDROXIDE | 2-Hydroxyethyltrimethylammonium Hydroxide | Sincaline | Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, hydroxide (1:1) | 2-hydroxyethyl(trimethyl)azanium;hydroxide | Bursine | KIZQNNOULOCVDM-UHFFFAOYSA-M | N,N

Storage

Conservar a 2-8°C,Protegido de la luz,Cargado con argón

Shipped In

Hielo húmedo

Descripción general

Aplicación：

El hidróxido de colina se utiliza como molécula precursora del neurotransmisor acetilcolina, está implicado en varias funciones incluyendo el control muscular y de la memoria muscular. Se utilizó como catalizador básico para reacciones de condensación aldol.

Specifications

Sinónimos

(.BETA.-HYDROXYETHYL)TRIMETHYLAMMONIUM HYDROXIDE | 2-Hydroxyethyltrimethylammonium Hydroxide | Sincaline | Ethanaminium, 2-hydroxy-N, N, N-trimethyl-, hydroxide (1:1) | 2-hydroxyethyl(trimethyl)azanium;hydroxide | Bursine | KIZQNNOULOCVDM-UHFFFAOYSA-M | N, N

Especificaciones y pureza

44 wt. % en H2O

Condiciones de almacenamiento de almacenamiento

Conservar a 2-8°C, Protegido de la luz, Cargado con argón

Enviado en

Hielo húmedo

Nombres e identificadores

• Sonrisas canónicas: C[N+](C)(C)CCO.[OH-]
• IUPAC Name: 2-hydroxyethyl(trimethyl)azanium;hydroxide
• InChIKey: KIZQNNOULOCVDM-UHFFFAOYSA-M
• INCHI: 1S/C5H14NO.H2O/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H2/q+1;/p-1
• Isómeros SMILES: C[N+](C)(C)CCO.[OH-]
• WGK Alemania: 3
• CAS alternativo: 62-49-7
• Peso molecular: 121.18
• Reaxy-Rn: 3912966
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3912966&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Clase Organonitrogen compounds
      • Subclass Quaternary ammonium salts

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Clase: Organonitrogen compounds
• Subclass: Quaternary ammonium salts
• Intermediate Tree Nodes: Not available
• Direct Parent: Cholines
• Alternative Parents: Tetraalkylammonium salts 1,2-aminoalcohols Primary alcohols Organopnictogen compounds Organic zwitterions Organic salts Organic oxoanionic compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Choline - Tetraalkylammonium salt - 1,2-aminoalcohol - Alkanolamine - Organic oxygen compound - Hydrocarbon derivative - Organic salt - Organic zwitterion - Primary alcohol - Organooxygen compound - Organic hydroxide - Organic oxide - Amine - Organopnictogen compound - Alcohol - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as cholines. These are organic compounds containing a N,N,N-trimethylethanolammonium cation.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Solubility in water: Completely miscible; Insoluble in Benzene,Toluene
• Sensibilidad: Light Sensitive,Air Sensitive,Heat Sensitive
• Índice de refracción: 1.427
• Peso molecular: 121.180 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 121.11 Da
• Monoisotopic Mass: 121.11 Da
• Topological Polar Surface Area: 21.200 Ų
• Heavy Atom Count: 8
• Formal Charge: 0
• Complexity: 46.500
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Referencias

1. Zhixing Huang, Yujie ChenYang, Xiaohang Wang, Rui Cai, Benyong Han.  (2023)  Biodiesel synthesis through soybean oil transesterification using choline-based amino acid ionic liquids as catalysts.  INDUSTRIAL CROPS AND PRODUCTS,      [PMID:] [10.1016/j.indcrop.2023.117869]

2. Yuanyuan Zhang, Wanxiang Zhang, Yan Wang, Shuhang Ren, Yucui Hou, Weize Wu.  (2023)  NH3 production from absorbed NO with synergistic catalysis of Pd/C and functionalized ionic liquids.  GREEN CHEMISTRY,  25  (15): (5999-6008).  [PMID:] [10.1039/D3GC00769C]

3. Jie Zhou, Shengnan Li, Jin Zhang, Fusui Luo, Yiwen Sun, Min Guan, Huili Ma, Qian Liu.  (2023)  Ionic liquid combined with bile acid pathway for oral delivery of rhGH.  JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.jddst.2023.104664]

4. Rui Peng, Yingying Guo, Jiage Liu, Huiyong Wang, Zhiyong Li, Xiaopeng Xuan, Yang Zhao, Jianji Wang.  (2023)  Liquid phase exfoliation of metal–organic frameworks in aqueous quaternary ammonium hydroxide solution enables highly efficient photocatalytic CO2 reduction.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2023.122153]

5. Bowen Jiang, Meiling Weng, Jigang An, Yuewei Fan, Jia Liu, Ying Liu, Ting Yu, Leizhi zheng, Guoqiang Yang, Zhibing Zhang.  (2023)  A simple hydroxypyridine ionic liquids for conversion of CO2 into quinazoline-2,4(1H,3H)-diones under atmospheric conditions.  CHINESE JOURNAL OF CHEMICAL ENGINEERING,      [PMID:] [10.1016/j.cjche.2023.04.003]

6. Fukang Deng, Kangchun Li, Qing Feng, Kedi Yang, Fuchuan Huang.  (2021)  Evaluation of frictional and rheological properties of choline/N-acetyl-l-proline ionic liquid modified with molecular aggregates of tea saponin derivatives.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2021.116649]

7. Pengfei Liu, Jiaojiao Zhang, Yan Qiao, Xianglin Hou, Yu Liu, Yingxiong Wang.  (2021)  Amino Acid Ionic Liquids Catalyzed d-Glucosamine into Pyrazine Derivatives: Insight from NMR Spectroscopy.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:33595305] [10.1021/acs.jafc.0c08032]

8. Xinyu Gao, Qing He, Gaojin Zhou, Ahmad Ali, Chen Yu, Shun Yao.  (2024)  Choline and amino acids-based ionic liquids (CABILs) for the preparation of new antibacterial coating with loofah and epoxy resin.  INDUSTRIAL CROPS AND PRODUCTS,      [PMID:] [10.1016/j.indcrop.2024.118093]

9. Yang Li, Qin Yu, Yi Lu, Haisheng He, Jianping Qi, Zongguang Tai, Zhongjian Chen, Quangang Zhu, Wei Wu.  (2024)  Enhanced transdermal delivery of insulin by choline-based ionic liquids.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,      [PMID:39603435] [10.1016/j.ijpharm.2024.125006]

10. Mingyuan Dou, Qing Feng, Jing Yang, Shuai Zou, Kangchun Li, Zhenpeng Li, Maoli Yang, Fuchuan Huang.  (2024)  Evaluation of rheological properties and tribological properties of choline/acetylamino acid ionic liquids at different frequencies.  WEAR,      [PMID:] [10.1016/j.wear.2024.205247]

11. Yitai Wang, Yinge Bai, Fukang Song, Shaojuan Zeng, Lulu Wang, Xiangping Zhang.  (2024)  Gas–Liquid Mass Transfer Characteristics of CO2 Absorption in Azole-Functionalized Ionic Liquid Anhydrous Solvents.  ENERGY & FUELS,      [PMID:] [10.1021/acs.energyfuels.4c05094]

12. Zhang Qing, Dai Ziliang, Zhang Lili, Wang Zhiguo.  (2024)  Insights into the critical role of anions in nanofibrillation of cellulose in deep eutectic solvents.  CELLULOSE,      [PMID:] [10.1007/s10570-024-06297-7]

13. Yuze Sheng, Xianzi Zheng, Lu Li, Haisheng He, Wei Wu, Yi Lu.  (2024)  Ionic co-aggregates based intravenous drug delivery: Evaluation on kinetics and distribution of the drug payloads and nanocarriers.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,      [PMID:39226987] [10.1016/j.ijpharm.2024.124657]

14. Ye-Ting Wang, Yu Chai, Xiao-Ping Zheng, Ya-Peng Du, Yu-Cang Zhang, Yan-Zhen Zheng.  (2025)  Pretreatment of tea stem by biocompatible ionic liquids for enhanced enzymatic hydrolysis of cellulose and formation of UV-blocking chitosan film.  FOOD CHEMISTRY,      [PMID:39914347] [10.1016/j.foodchem.2025.143172]

15. Xueqi Sun, Shaojuan Zeng, Guilin Li, Yinge Bai, Minghua Shang, Jian Zhang, Xiangping Zhang.  (2024)  Selective CO2 separation through physicochemical absorption by triazole-functionalized ionic liquid binary absorbents.  AICHE JOURNAL,      [PMID:] [10.1002/aic.18376]

16. Yang Hu, Xiaoyu Zhang, Lin Zhang, Wensheng Yang.  (2025)  Synthesis of Multishelled Silica Particles by Using Choline Hydroxide as Catalyst.  LANGMUIR,      [PMID:39909842] [10.1021/acs.langmuir.4c04758]

17. Xuedan Hou, Guojian Feng, Zishi Chen, Hongjie Wu, Hengyun Zhao, Shilin Cao, Jason P. Hallett.  (2024)  Tailoring a suitable partner system for cholinium cation to build effective solvents for biomass deconstruction.  GREEN CHEMISTRY,  26  (10): (5977-5987).  [PMID:] [10.1039/D3GC05208G]

18. Meng Zeng, Ping Deng, Qin Li, Qi Tang, Jixiang Li, Liangke Zhang.  (2025)  The H2S-releasing multifunctional composite ionic liquid facilitates topical melittin delivery for psoriasis treatment through RONS scavenging and inflammation inhibition.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.160972]

19. Dawei Zhen, Yirong Qiao, Fengmao Liu, Xiaohui Liu, Shouhe Pan, Qingrong Peng.  (2025)  Unveiling the interaction between micelles of different surface-active ionic liquids and peptide drug HPV16E749-57.  Materials Today Chemistry,      [PMID:] [10.1016/j.mtchem.2025.102662]

20. Huanhuan Dong, Xiaoyu Ji, Zhao Li, Junxiang Guo, Shan Peng.  (2025)  Rapid photothermal wrinkled MXene/hollow CuCo-MOF@PDMS sponge for fast viscous oils separation.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2025.134725]

21. Ye-Ting Wang, Qing-Ping Zheng, Yu Chai, Yu-Cang Zhang, Yan-Zhen Zheng.  (2025)  Efficient pretreatment of tea stems using biocompatible ionic liquid and monoethanolamine: Toward improved enzymatic hydrolysis and UV-blocking PVA-LNPs composite films.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.168378]

22. Meng Liu, Guoqiang Han, Yaxu Sun, Lei Zhang, Qi Tang, Kaixia Liang, Qinqin Xia, Shuo Dou, Xiaoxue Song, Haipeng Yu, Yongzhuang Liu.  (2025)  Scalable Extraction of High-Purity Hemicellulose from Biomass via Urea-Assisted Tetramethylammonium Hydroxide and Membrane Separation.  ChemSusChem,      [PMID:41024744] [10.1002/cssc.202501780]

23. Mingyuan Dou, Qing Feng, Kangchun Li, Zhenpeng Li, Fuchuan Huang, Fukang Deng.  (2025)  Choline amino acid ionic liquid micelles enhance the oxidation resistance and tribological properties of MXene.  TRIBOLOGY INTERNATIONAL,      [PMID:] [10.1016/j.triboint.2025.110790]

24. Haozhan Chu, Shaojuan Zeng, Xiangping Zhang, Guoxiong Zhan, Bo Wang, Hongyu Zhang, Sheng Zhong, Wei Liu.  (2025)  Cobalt-modified MCM-41 catalysts with multiple acidic sites for energy-efficient CO2 desorption of functionalized ionic liquid absorbents.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2025.133571]

25. Fang Miao, Lun Xiong, Mingquan Jiang, Guolin Yang, Hui Zhu, Jiehong Lei.  (2025)  Choline hydroxide‑functionalized silica aerogel for efficient capture and immobilization of radioactive iodine vapor.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2025.137406]

26. Chen Yue, Chen Qinyi, Ma Yuanyuan, Zhang Cheng, Xu Jie, Li Kejing, Sun Yajie, Su Xinge, Wei Mingguang, Bao Rui, Ding Tong, Tang Longguang, Yu Wenying, Ju Shenghong, Fan Wenpei.  (2026)  In situ self-assembled cell reservoir hydrogel for maneuvering multistage radioimmunotherapy.  Nature Communications,      [PMID:41565700] [10.1038/s41467-026-68490-5]