Chondroitin sulfate B sodium salt - ≥90%, lyophilized powder,from porcine intestinal mucosa,lyophilized powder;average MW 30-40KDa , CAS No.54328-33-5

CAS: 54328-33-5 Cat. No.: C477635

GRADE & PURITY ≥90%, lyophilized powder,from porcine intestinal mucosa,lyophilized powder;average MW 30-40KDa

Synonyms

Dermatan sulfate sodium salt | β-Heparin

Storage

Store at 2-8°C,Protected from light

Shipped In

Wet ice

Descripción general

Chondroitin, a glucosaminoglycan (GAG), is a polysaccharide chain of alternating units of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcA) that can be sulfated on the either or both GalNAc and GlcA units. Chondroitin and its sulfates are frequently attached to proteins to form proteoglycans. Chondroitin sulfate B (Dermatam sulfate) is a component of proteoglycans such as decorin, biglycan and versican. Chondroitin sulfate B is used to study β peptide (1-42) cytotoxicity. 

Application

Chondroitin sulfate B may be used to study its roles as a biomolecule receptor, mediator of cell signaling and cell binding molecule. It may be used to compare its properties to those of chondroitin sulfate A and chondroitin sulfate C. Chondroitin sulfate B is used to study β peptide(1-42) cytotoxicity.

Composition

Chondroitin Sulfate B is an acidic mucopolysaccharide found in cartilage, skin, cornea, and umbilical cord. It is composed of alternating N-acetylgalactosamine, L-iduronic acid, and sulfate residues in equimolar quantities where carbon 4 of the N-acetylgalactosamines is sulfated.  

Specifications

Sinónimos

Dermatan sulfate sodium salt | β-Heparin

Especificaciones y pureza

≥90%, lyophilized powder, from porcine intestinal mucosa, lyophilized powder;average MW 30-40KDa

Mecanismos bioquímicos y fisiológicos

As a large, negatively charged, hydrophilic molecule that is too inflexible to fold into a compact globular structure, chondroitin sulfate molecules form porous hydrated gels, providing mechanical support to tissue and allowing rapid diffusion of water-so

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C, Protected from light

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥90%

Nombres e identificadores

• Pubchem Sid: 504753491
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504753491
• Sonrisas canónicas: CC(=O)NC1C(C(C(OC1O)CO)OS(=O)(=O)[O-])OC2C(C(C(C(O2)C(=O)[O-])O)O)O
• IUPAC Name: (2R,3S,4S,5R,6R)-6-[(2R,3R,4R,5R,6R)-3-acetamido-2-hydroxy-6-(hydroxymethyl)-5-sulfonatooxyoxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate
• InChIKey: AVJBPWGFOQAPRH-FWMKGIEWSA-L
• INCHI: 1S/C14H23NO15S/c1-3(17)15-5-10(9(30-31(24,25)26)4(2-16)27-13(5)23)28-14-8(20)6(18)7(19)11(29-14)12(21)22/h4-11,13-14,16,18-20,23H,2H2,1H3,(H,15,17)(H,21,22)(H,24,25,26)/p-2/t4-,5-,6+,7+,8-,9+,10-,11-,13-,14-/m1/s1
• Isómeros SMILES: CC(=O)N[C@@H]1[C@H]([C@H]([C@H](O[C@H]1O)CO)OS(=O)(=O)[O-])O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](O2)C(=O)[O-])O)O)O
• Reaxy-Rn: 42087677
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=42087677&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Clase Organooxygen compounds
      • Subclass Carbohydrates and carbohydrate conjugates
        • Level5 Aminosaccharides
          • Level6 Amino sugars
            • Level7 Acylaminosugars

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Clase: Organooxygen compounds
• Subclass: Carbohydrates and carbohydrate conjugates
• Intermediate Tree Nodes: Aminosaccharides - Amino sugars
• Direct Parent: Acylaminosugars
• Alternative Parents: Disaccharide sulfates N-acyl-alpha-hexosamines O-glucuronides O-glycosyl compounds Beta hydroxy acids and derivatives Pyrans Oxanes Alkyl sulfates Sulfuric acid monoesters Acetamides Hemiacetals Secondary carboxylic acid amides Secondary alcohols Polyols Oxacyclic compounds Carboxylic acids Monocarboxylic acids and derivatives Acetals Organonitrogen compounds Primary alcohols Organic oxides Hydrocarbon derivatives Organopnictogen compounds Carbonyl compounds Organic anions
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Acylaminosugar - N-acyl-alpha-hexosamine - Disaccharide sulfate - 1-o-glucuronide - O-glucuronide - Glucuronic acid or derivatives - Disaccharide - Glycosyl compound - O-glycosyl compound - Beta-hydroxy acid - Hydroxy acid - Sulfuric acid ester - Oxane - Pyran - Sulfuric acid monoester - Sulfate-ester - Alkyl sulfate - Organic sulfuric acid or derivatives - Acetamide - Carboxamide group - Secondary carboxylic acid amide - Secondary alcohol - Hemiacetal - Polyol - Carboxylic acid derivative - Carboxylic acid - Oxacycle - Acetal - Monocarboxylic acid or derivatives - Organoheterocyclic compound - Organic oxide - Organopnictogen compound - Carbonyl group - Hydrocarbon derivative - Alcohol - Organic nitrogen compound - Organonitrogen compound - Primary alcohol - Organic anion - Aliphatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as acylaminosugars. These are organic compounds containing a sugar linked to a chain through N-acyl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: H2O: 5mg/mL, clear, colorless
• Sensibilidad: light & moisture sensitive

Referencias

1. Qu Fei, Li Xiaonan, Lv Xiaoxia, You Jinmao, Han Wenli.  (2018)  Highly selective metal–organic framework-based sensor for protamine through photoinduced electron transfer.  JOURNAL OF MATERIALS SCIENCE,  54  (4): (3144-3155).  [PMID:] [10.1007/s10853-018-3041-6]

2. Yiwen Jing, Xiangfan Yu, Lei Liu, Zhenyu Ma, Xukai Jiang, Li Xu, Min Xiao.  (2026)  Biochemical Characterization and Substrate Specificity Mechanism of an Exolytic Hyaluronate Lyase SinHL from Streptococcus iniae QMA0131.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:41571584] [10.1021/acs.jafc.5c12120]

3. Qingxia Yuan, Zidong Liu, Yue Yao, Haiqiong Ma, Jiewen Fu, Xiang Shi, Jinying Huang, Yonghong Liu, Longyan Zhao.  (2026)  A novel glycosaminoglycan from the brittlestar Trichaster palmiferus: structure and low-bleed anticoagulant–antithrombotic action.  CARBOHYDRATE POLYMERS,      [PMID:41714007] [10.1016/j.carbpol.2026.125036]

4. Nana Ma, Xueling Dong, Ruinan Li, Chuang Du, Yawen Wang, Jiaxin Bai, Run Ran, Xulin Liu, Dianshuo Zhang, Haikui Zou.  (2026)  Coptisine Chloride: A Natural Isoquinoline Alkaloid as a Dual-Responsive Aggregation-Induced Emission Sensor for Heparin and Protamine.  Chemosensors,  14  (2): (51).  [PMID:] [10.3390/chemosensors14020051]