Selective dehydrodipeptidase I inhibitor (K i = 0.11 µM). Inhibits leukotriene D 4 hydrolase (K i = 0.11 µM). Potentiates the antibiotic activity of Imipenem. Shows nephroprotective effects in vivo.
Condiciones de almacenamiento de almacenamiento
Protected from light, Store at -20°C, Argon charged, Desiccated
Enviado en
Ice chest + Ice pads
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Tipo de acción
INHIBITOR
Mecanismo de acción
Renal dipeptidase inhibitor
Nota
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This compound belongs to the class of organic compounds known as n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom.
External Descriptors
organic sodium salt
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Soluble in water to 50 mM and in DMSO to 25 mM (with warming)
Sensibilidad
Moisture & Heat & Light Sensitive
Punto de fusión (°C)
>160°C
Peso molecular
380.400 g/mol
XLogP3
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
7
Rotatable Bond Count
11
Exact Mass
380.138 Da
Monoisotopic Mass
380.138 Da
Topological Polar Surface Area
158.000 Ų
Heavy Atom Count
25
Formal Charge
0
Complexity
525.000
Isotope Atom Count
0
Defined Atom Stereocenter Count
2
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
1
Undefined Bond Stereocenter Count
0
The total count of all stereochemical bonds
1
Covalently-Bonded Unit Count
2
Calculadoras de soluciones
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Reseñas
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