Ciprofloxacin Hydrochloride Monohydrate - analytical standard , CAS No.86393-32-0

CAS: 86393-32-0 Cat. No.: C114253 Peso molecular: 367.81(as Anhydrous) Número EC: 617-845-1

GRADE & PURITY Analytical standard

Synonyms

Microgan | Phaproxin | Bay-o-9867 monohydrate | Ciprofloxacin (hydrochloride monohydrate) | Catex | Ciprofur | Plenolyt | Renator | RX710 | ProquinXR | 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid hydrate hydrochloride | ciprof

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Sinónimos

Microgan | Phaproxin | Bay-o-9867 monohydrate | Ciprofloxacin (hydrochloride monohydrate) | Catex | Ciprofur | Plenolyt | Renator | RX710 | ProquinXR | 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid hydrate hydrochloride | ciprof

Especificaciones y pureza

analytical standard

Mecanismos bioquímicos y fisiológicos

Fluoroquinolone antibiotic. Bacteriostatic agent. Interferes with DNA gyrase causing DNA rewinding stopping DNA and protein synthesis. Active in vivo and in vitro.

Condiciones de almacenamiento de almacenamiento

Protected from light, Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Analytical standard

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Nombres e identificadores

• Sonrisas canónicas: C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCNCC4)F)C(=O)O.O.Cl
• IUPAC Name: 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid;hydrate;hydrochloride
• InChIKey: ARPUHYJMCVWYCZ-UHFFFAOYSA-N
• INCHI: 1S/C17H18FN3O3.ClH.H2O/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;;/h7-10,19H,1-6H2,(H,23,24);1H;1H2
• Isómeros SMILES: C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCNCC4)F)C(=O)O.O.Cl
• WGK Alemania: 3
• Peso molecular: 367.81(as Anhydrous)
• Reaxy-Rn: 13474821
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=13474821&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Quinolines and derivatives
      • Subclass Quinoline carboxylic acids

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Quinolines and derivatives
• Subclass: Quinoline carboxylic acids
• Intermediate Tree Nodes: Not available
• Direct Parent: Quinoline carboxylic acids
• Alternative Parents: N-arylpiperazines Fluoroquinolones Aminoquinolines and derivatives Hydroquinolones Haloquinolines Hydroquinolines Pyridinecarboxylic acids Dialkylarylamines Aryl fluorides Benzenoids Vinylogous amides Heteroaromatic compounds Amino acids Azacyclic compounds Carboxylic acids Dialkylamines Monocarboxylic acids and derivatives Organooxygen compounds Organic oxides Organofluorides Organopnictogen compounds Hydrochlorides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Quinoline-3-carboxylic acid - Fluoroquinolone - N-arylpiperazine - Aminoquinoline - Haloquinoline - Dihydroquinolone - Dihydroquinoline - Pyridine carboxylic acid - Pyridine carboxylic acid or derivatives - Dialkylarylamine - Tertiary aliphatic/aromatic amine - Benzenoid - Aryl fluoride - Aryl halide - Pyridine - 1,4-diazinane - Piperazine - Heteroaromatic compound - Vinylogous amide - Tertiary amine - Amino acid - Amino acid or derivatives - Azacycle - Secondary amine - Carboxylic acid derivative - Carboxylic acid - Secondary aliphatic amine - Monocarboxylic acid or derivatives - Organopnictogen compound - Organic oxygen compound - Amine - Hydrocarbon derivative - Organic nitrogen compound - Organic oxide - Hydrochloride - Organohalogen compound - Organofluoride - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as quinoline carboxylic acids. These are quinolines in which the quinoline ring system is substituted by a carboxyl group at one or more positions.
• External Descriptors: hydrate

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mecanismos de acción

Propiedades químicas y físicas

• Sensibilidad: Moisture sensitive；Light sensitive
• Peso molecular: 385.800 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 3
• Exact Mass: 385.12 Da
• Monoisotopic Mass: 385.12 Da
• Topological Polar Surface Area: 73.900 Ų
• Heavy Atom Count: 26
• Formal Charge: 0
• Complexity: 571.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3

Referencias

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18. Muhammad Noman, Guangwei Yu, Dinkayehu Tsegaye Awugichew, Xinlin Li.  (2024)  Synthesis of surficial-modified green biochar catalyst generated by biogas residue biochar and potential application for catalytic ozonation degradation of ciprofloxacin.  ENVIRONMENTAL RESEARCH,      [PMID:38824988] [10.1016/j.envres.2024.119314]

19. Yue He, Shuang Xiao, Jiabin Zhou, Dan Liu, Zhipu Wang.  (2025)  Visible light-peroxomonosulfate coactivation via CuOx/Fe2O3 composites for efficient degradation of tetracycline and bimetallic mechanisms.  Journal of Water Process Engineering,      [PMID:] [10.1016/j.jwpe.2025.108363]

20. Rui Liu, Bolin Wu, Rijia Liu, Xin Zhang, Yuan Sun, Jing Ma.  (2025)  Development of Ag/ZIF-67/g-C3N4/GCE electrochemical sensor to detect chloramphenicol with the assistance of machine learning.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.113510]

21. Shuai Dou, Qi-Jun Zhang, Peng Wu, Hui-Wen Huo, Lu-Bin Zhong, Yu-Ming Zheng.  (2025)  Facile preparation of hierarchical porous MOF-based hollow carbon nanofiber mats using a polymer-blend electrospinning strategy for efficient adsorption of ciprofloxacin.  Journal of Environmental Sciences,      [PMID:41177602] [10.1016/j.jes.2025.04.029]

22. Kaixin Sun, Bo Gong, Chang Xu, Shan Zhao, Shuguang Wang, Le Ren, Chao Song.  (2025)  Enhancing the degradation of ciprofloxacin and levofloxacin by peroxydisulfate (PDS): Multiple roles of co-existing copper ion.  Journal of Environmental Chemical Engineering,  13  (6): (120491).  [PMID:] [10.1016/j.jece.2025.120491]