cis-ACBD (1-Aminocyclobutane-1 , CAS No.73550-55-7

CAS: 73550-55-7 Cat. No.: A276100 Peso molecular: 159.14 Número EC: 118-554-8

Synonyms

1-Aminocyclobutane-cis-1,3-dicarboxylic acid | cis-2,4-methanoglutamate | A803777 | AKOS006239508 | trans-ABCD | 1,3-Cyclobutanedicarboxylic acid, 1-amino-, trans-, hydrate | HY-100616 | FT-0642876 | SCHEMBL7530916 | 1-aminocyclobutane-trans-1,3-dicarboxy

Storage

Room temperature

Shipped In

Normal

Descripción general

Store at Room Temperature. The product can be stored for up to 12 months.

Specifications

Sinónimos

1-Aminocyclobutane-cis-1, 3-dicarboxylic acid | cis-2, 4-methanoglutamate | A803777 | AKOS006239508 | trans-ABCD | 1, 3-Cyclobutanedicarboxylic acid, 1-amino-, trans-, hydrate | HY-100616 | FT-0642876 | SCHEMBL7530916 | 1-aminocyclobutane-trans-1, 3-dicarboxy

Mecanismos bioquímicos y fisiológicos

Selective, competitive L-glutamate uptake inhibitor (IC 50 = 30 μM). Increases basal and potassium evoked D-aspartate release.

Condiciones de almacenamiento de almacenamiento

Room temperature

Enviado en

Normal

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Nombres e identificadores

• Sonrisas canónicas: C1C(CC1(C(=O)O)N)C(=O)O
• IUPAC Name: 1-aminocyclobutane-1,3-dicarboxylic acid
• InChIKey: GGMYWPBNZXRMME-UHFFFAOYSA-N
• INCHI: 1S/C6H9NO4/c7-6(5(10)11)1-3(2-6)4(8)9/h3H,1-2,7H2,(H,8,9)(H,10,11)
• Isómeros SMILES: C1C(CC1(C(=O)O)N)C(=O)O
• Peso molecular: 159.14
• Reaxy-Rn: 24734301
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24734301&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Alpha amino acids
              • Level8 L-alpha-amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids
• Direct Parent: L-alpha-amino acids
• Alternative Parents: D-alpha-amino acids Dicarboxylic acids and derivatives Amino acids Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic homomonocyclic compounds
• Substituents: D-alpha-amino acid - L-alpha-amino acid - Dicarboxylic acid or derivatives - Amino acid - Carboxylic acid - Hydrocarbon derivative - Organopnictogen compound - Organic oxygen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Organic nitrogen compound - Carbonyl group - Amine - Organic oxide - Aliphatic homomonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in 1eq. NaOH to 50 mM
• Peso molecular: 159.140 g/mol
• XLogP3: -3.500
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 159.053 Da
• Monoisotopic Mass: 159.053 Da
• Topological Polar Surface Area: 101.000 Ų
• Heavy Atom Count: 11
• Formal Charge: 0
• Complexity: 207.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1