cis-Diammineplatinum dichloride - Moligand™, Pt,65% , CAS No.15663-27-1

CAS: 15663-27-1 Cat. No.: D109812 Peso molecular: 300.1 Número EC: 239-733-8
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. Pt,65%
Synonyms
Cisplatin
Storage
Protected from light,Room temperature,Argon charged,Desiccated,Cool
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
100mg
D109812-100mg
5
32,90US$
250mg
D109812-250mg
3

57,90US$

69,90US$
Guardar 12,00 US$ (17.17%)
1g
D109812-1g
3
229,90US$
5g
D109812-5g
2
939,90US$
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, Pt,65% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Room temperature,Argon charged,Desiccated,Cool Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 57 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos
Cisplatin
Especificaciones y pureza
Moligand™, Pt, 65%
Mecanismos bioquímicos y fisiológicos
Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links.Potent, broad spectrum antineoplastic agent. Cytotoxic, crosslinks DNA to impair replication and transcription. Arrests cell cycle in G 2 /M phase. Antitumor, cros
Condiciones de almacenamiento de almacenamiento
Protected from light, Room temperature, Argon charged, Desiccated, Cool
Enviado en
Normal
Grado
Moligand™
Nota
Unstable; make up solutions fresh and use immediately. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Nombres e identificadores
Sonrisas canónicasN.N.Cl[Pt]Cl
InChIKeyLXZZYRPGZAFOLE-UHFFFAOYSA-L
INCHI1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
WGK Alemania 3
RTECS TP2450000
Número ONU 2928
Grupo de embalaje I
Peso molecular 300.1

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomInorganic compounds
SuperclassMixed metal/non-metal compounds
ClaseTransition metal salts
SubclassTransition metal chlorides
Intermediate Tree Nodes Not available
Direct ParentTransition metal chlorides
Alternative Parents Inorganic chloride salts  
Molecular FrameworkNot available
Substituents Transition metal chloride - Inorganic chloride salt - Inorganic salt
DescripciónThis compound belongs to the class of inorganic compounds known as transition metal chlorides. These are inorganic compounds in which the largest halogen atom is Chlorine, and the heaviest metal atom is a transition metal.
External Descriptors diamminedichloroplatinum
Estructura 3D
Modelo de Estructura Química Interactiva





Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

33 results found

Lot NumberCertificate TypeFechaArticulo
E2621673Certificate of AnalysisMay 12, 2026 D109812
E2621318Certificate of AnalysisMay 12, 2026 D109812
E2621315Certificate of AnalysisMay 12, 2026 D109812
E2621314Certificate of AnalysisMay 12, 2026 D109812
E2421021Certificate of AnalysisFeb 05, 2026 D109812
C2405078Certificate of AnalysisDec 10, 2025 D109812
I2524282Certificate of AnalysisSep 08, 2025 D109812
I2524284Certificate of AnalysisSep 08, 2025 D109812
I2524283Certificate of AnalysisSep 08, 2025 D109812
D2627084Certificate of AnalysisJun 28, 2025 D109812
H2519392Certificate of AnalysisJun 28, 2025 D109812
H2519390Certificate of AnalysisJun 28, 2025 D109812
H2519391Certificate of AnalysisJun 28, 2025 D109812
F2512161Certificate of AnalysisJun 21, 2025 D109812
D2514062Certificate of AnalysisMay 05, 2025 D109812
D2306134Certificate of AnalysisJan 13, 2025 D109812
L2419386Certificate of AnalysisDec 25, 2024 D109812
G2412026Certificate of AnalysisJul 25, 2024 D109812
K2413293Certificate of AnalysisJul 23, 2024 D109812
G2416073Certificate of AnalysisJun 14, 2024 D109812
G2416107Certificate of AnalysisJun 14, 2024 D109812
C2415143Certificate of AnalysisMar 21, 2024 D109812
L2107495Certificate of AnalysisSep 20, 2023 D109812
L2107580Certificate of AnalysisSep 20, 2023 D109812
L2425243Certificate of AnalysisSep 20, 2023 D109812
I2322118Certificate of AnalysisNov 14, 2022 D109812
L2305010Certificate of AnalysisNov 14, 2022 D109812
D2306133Certificate of AnalysisNov 14, 2022 D109812
C2420027Certificate of AnalysisNov 14, 2022 D109812
G2308207Certificate of AnalysisJun 01, 2022 D109812
F2215374Certificate of AnalysisJun 01, 2022 D109812
F2215373Certificate of AnalysisJun 01, 2022 D109812
F2215372Certificate of AnalysisJun 01, 2022 D109812

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Propiedades químicas y físicas
SolubilidadSoluble in DMSO (25 mg/ml), water (0.25 g/100ml) at 25 °C, ethanol (<1 mg/ml) at 25 °C, and DMF (16 mg/ml)
SensibilidadMoisture sensitive & Light sensitive
Punto de fusión (°C)270°C
Preguntas frecuentes y artículos
Citations of This Product
Referencias
1. Jiang Hao, Tian Hailong, Wang Zhihan, Li Bowen, Chen Rui, Luo Kangjia, Lu Shuaijun, Nice Edouard C., Zhang Wei, Huang Canhua, Zhou Yuping, Zheng Shaojiang, Gao Feng.  (2023)  Laser-activatable oxygen self-supplying nanoplatform for efficiently overcoming colorectal cancer resistance by enhanced ferroptosis and alleviated hypoxic microenvironment.  Biomaterials Research,  27  (1): (1-20).  [PMID:37742011] [10.1186/s40824-023-00427-1]
2. Leyi Fang, Xiao-Tong Pan, Kang Liu, Dechen Jiang, Deju Ye, Li-Na Ji, Kang Wang, Xing-Hua Xia.  (2023)  Surface-Roughened SERS-Active Single Silver Nanowire for Simultaneous Detection of Intracellular and Extracellular pHs.  ACS Applied Materials & Interfaces,      [PMID:37071781] [10.1021/acsami.3c00844]
3. Yunfan Liu, Jiazhou Zhai, Fei Qin, Liping Gao, Yongxin She, Mengqiang Wang.  (2023)  Protective role of polyphenol extract from highland barley against cisplatin-induced renal toxicity and mitochondrial damage in rats.  FOOD SCIENCE AND TECHNOLOGY RESEARCH,      [PMID:] [10.3136/fstr.FSTR-D-21-00284]
4. Yi Xiao, Haomin Yi, Jingzhi Zhu, Suhua Chen, Guofang Wang, Yilong Liao, Yuanyuan Lei, Liyin Chen, Xingcai Zhang, Fangfu Ye.  (2022)  Evaluation of DNA adduct damage using G-quadruplex-based DNAzyme.  Bioactive Materials,      [PMID:36406255] [10.1016/j.bioactmat.2022.10.002]
5. Zhou Yafu, Yan Jianhua, Chen Huiguo, Zhou Wenwu, Yang Jinsong.  (2022)  MicroRNA-133a-3p Inhibits Lung Adenocarcinoma Development and Cisplatin Resistance through Targeting GINS4.  CELLS TISSUES ORGANS,      [PMID:36273455] [10.1159/000527684]
6. Xue-qi Liu, Ming-ming Liu, Ling Jiang, Li Gao, Yao Zhang, Yue-bo Huang, Xian Wang, Wei Zhu, Han-xu Zeng, Xiao-ming Meng, Yong-gui Wu.  (2022)  A novel small molecule Hsp90 inhibitor, C-316-1, attenuates acute kidney injury by suppressing RIPK1-mediated inflammation and necroptosis.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:35588657] [10.1016/j.intimp.2022.108849]
7. Yaodong Yi, Liping Li, Feifeng Song, Ping Li, Mingyang Chen, Shixin Ni, Hengbin Zhang, Hui Zhou, Su Zeng, Huidi Jiang.  (2021)  L-tetrahydropalmatine reduces oxaliplatin accumulation in the dorsal root ganglion and mitochondria through selectively inhibiting the transporter-mediated uptake thereby attenuates peripheral neurotoxicity.  TOXICOLOGY,      [PMID:34252480] [10.1016/j.tox.2021.152853]
8. Liuwei Zhang, Ming Qian, Hongyan Cui, Shuang Zeng, Jingyun Wang, Qixian Chen.  (2021)  Spatiotemporal Concurrent Liberation of Cytotoxins from Dual-Prodrug Nanomedicine for Synergistic Antitumor Therapy.  ACS Applied Materials & Interfaces,      [PMID:33525873] [10.1021/acsami.0c21422]
9. Zheng Di-Wei, Pan Pei, Chen Ke-Wei, Fan Jin-Xuan, Li Chu-Xin, Cheng Han, Zhang Xian-Zheng.  (2020)  An orally delivered microbial cocktail for the removal of nitrogenous metabolic waste in animal models of kidney failure.  Nature Biomedical Engineering,  (9): (853-862).  [PMID:32632226] [10.1038/s41551-020-0582-1]
10. Cui Li, Liping Li, Yaodong Yi, Wei Wang, Jingqun Yuan, Fuqing Tan, Danbo Fang, Su Zeng, Hui Zhou, Huidi Jiang.  (2020)  L-tetrahydropalmatine attenuates cisplatin-induced nephrotoxicity via selective inhibition of organic cation transporter 2 without impairing its antitumor efficacy.  BIOCHEMICAL PHARMACOLOGY,      [PMID:32389634] [10.1016/j.bcp.2020.114021]
11. Peng-Chao Zhang, Xiao Liu, Man-Mei Li, Yan-Yan Ma, Hong-Tao Sun, Xu-Yan Tian, Yan Wang, Min Liu, Liang-Shun Fu, Yi-Fei Wang, Hong-Yuan Chen, Zhong Liu.  (2019)  AT-533, a novel Hsp90 inhibitor, inhibits breast cancer growth and HIF-1α/VEGF/VEGFR-2-mediated angiogenesis in vitro and in vivo.  BIOCHEMICAL PHARMACOLOGY,      [PMID:31863779] [10.1016/j.bcp.2019.113771]
12. Chen Xiao, Hang Hu, Hai Yang, Si Li, Hui Zhou, Jian Ruan, Yuting Zhu, Xiangliang Yang, Zifu Li.  (2018)  Colloidal hydroxyethyl starch for tumor-targeted platinum delivery.  Nanoscale Advances,  (3): (1002-1012).  [PMID:36133197] [10.1039/C8NA00271A]
13. Guangjian Zeng, Meiying Liu, Ruming Jiang, Chunning Heng, Qiang Huang, Liucheng Mao, Junfeng Hui, Fengjie Deng, Xiaoyong Zhang, Yen Wei.  (2017)  Surface grafting of Eu3 + doped luminescent hydroxyapatite nanomaterials through metal free light initiated atom transfer radical polymerization for theranostic applications.  Materials Science & Engineering C-Materials for Biological Applications,      [PMID:28532048] [10.1016/j.msec.2017.03.261]
14. Xiangxiang Liu, Bowei Liu, Sijia Gao, Zhaocheng Wang, Ye Tian, Man Wu, Shidong Jiang, Zhongwei Niu.  (2017)  Glyco-decorated tobacco mosaic virus as a vector for cisplatin delivery.  Journal of Materials Chemistry B,  (11): (2078-2085).  [PMID:32263681] [10.1039/C7TB00100B]
15. Huang Wuren, Zhang Jie, Yang Bing, Beerntsen Brenda T., Song Hongsheng, Ling Erjun.  (2016)  DNA duplication is essential for the repair of gastrointestinal perforation in the insect midgut.  Scientific Reports,  (1): (1-10).  [PMID:26754166] [10.1038/srep19142]
16. Xiali Yin, Yaohua Ke, Ying Liang, Shuxian Zhang, Ziqi Chen, Lixia Yu, Ming Jiang, Qin Liu, Xiaoping Gu.  (2024)  An Immune-Enhancing Injectable Hydrogel Loaded with Esketamine and DDP Promotes Painless Immunochemotherapy to Inhibit Breast Cancer Growth.  Advanced Healthcare Materials,      [PMID:39118566] [10.1002/adhm.202401373]
17. Keli Liu, Shaofan Hu, Reziyamu Wufuer, Qun Zhang, Lu Qiu, Zhengwen Zhang, Meng Wang, Yiguo Zhang.  (2025)  Deficiency of DDI2 suppresses liver cancer progression by worsening cell survival conditions.  FREE RADICAL BIOLOGY AND MEDICINE,      [PMID:40049338] [10.1016/j.freeradbiomed.2025.03.003]
18. Reziyamu Wufuer, Keli Liu, Jing Feng, Meng Wang, Shaofan Hu, Feilong Chen, Shanshan Lin, Yiguo Zhang.  (2024)  Distinct mechanisms by which Nrf1 and Nrf2 as drug targets contribute to the anticancer efficacy of cisplatin on hepatoma cells.  FREE RADICAL BIOLOGY AND MEDICINE,      [PMID:] [10.1016/j.freeradbiomed.2024.01.031]
19. Lele Xu, Yuting Chen, Tao Wu, Jiaqi Fan, Yuying Hu, Xuefeng Gao, Yuliang Wang, Tao Chen, Xueting Zhao, Min Zeng, Fei Wang, Qingyou Zheng, Xiaojuan Pei, Dinglan Wu.  (2024)  DNA damage-mediated FTO downregulation promotes CRPC progression by inhibiting FOXO3a via an m6A-dependent mechanism.  iScience,      [PMID:39238652] [10.1016/j.isci.2024.110505]
20. Wu Yuanlin, Zhang Jiandong, Zhao Junjun, Wang Bin.  (2024)  Folate-modified liposomes mediate the co-delivery of cisplatin with miR-219a-5p for the targeted treatment of cisplatin-resistant lung cancer.  BMC Pulmonary Medicine,  24  (1): (1-14).  [PMID:38561695] [10.1186/s12890-024-02938-6]
21. Lujuan Han, Xiaohan Xiang, Yuhui Fu, Sisi Wei, Cong Zhang, Lei Li, Yueping Liu, Huilai Lv, Lianmei Zhao, Baoen Shan.  (2024)  Periplcymarin targets glycolysis and mitochondrial oxidative phosphorylation of esophageal squamous cell carcinoma: Implication in anti-cancer therapy.  PHYTOMEDICINE,      [PMID:38522311] [10.1016/j.phymed.2024.155539]
22. Zou Lan, Wang Rujing, Zhao Mengnan, Li Yuke, Sun Chen, Xie Jinjin, Chen Yan, Jing Qian, Mi Dandan, Shi Sanjun.  (2025)  PLGA confers upon conventional nonfluorescent molecules luminescent properties to trigger 1O2-induced pyroptosis and immune response in tumors.  JOURNAL OF NANOBIOTECHNOLOGY,  23  (1): (1-23).  [PMID:39844156] [10.1186/s12951-025-03094-7]
23. Song Zeyu, Li Zhenyuan, Pan Tao, Liu Teng, Gong Baifang, Wang Zhixia, Liu Ke, Fan Huaying.  (2024)  Protopanaxadiol prevents cisplatin-induced acute kidney injury by regulating ferroptosis.  JOURNAL OF PHARMACY AND PHARMACOLOGY,      [PMID:38708970] [10.1093/jpp/rgae050]
24. Yuru Pang, Qiqi Meng, Yangchen Cui, Shiyi Liu, Huihui Jiang, Chenlan Xu, Yan An, Yang Jiao, Qi Zhang, Jihua Nie.  (2025)  Radiosensitization effect of iridium (III) complex on lung cancer cells via mitochondria apoptosis pathway.  Frontiers in Pharmacology,      [PMID:40230690] [10.3389/fphar.2025.1562228]
25. Sui Xue, Gao Bingqing, Zhang Liu, Wang Yanmin, Ma Junnan, Wu Xingchen, Zhou Chenyu, Liu Min, Zhang Lin.  (2024)  Scutellaria barbata D.Don and Hedyotis diffusa Willd herb pair combined with cisplatin synergistically inhibits ovarian cancer progression through modulating oxidative stress via NRF2-FTH1 autophagic degradation pathway.  Journal of Ovarian Research,  17  (1): (1-17).  [PMID:39702302] [10.1186/s13048-024-01570-6]
26. Tang Wei, Zong Shimin, Du Peiyu, Yu Xuan, Li Ting, Liu Bo, Zhong Yu, Lei Wenyang, Yu Wenting, Xiao Hongjun.  (2025)  SIRT3 regulates PFKFB3-mediated glycolysis to attenuate cisplatin-induced ototoxicity both in vivo and in vitro.  ARCHIVES OF TOXICOLOGY,      [PMID:39945816] [10.1007/s00204-025-03975-8]
27. Borui Zhao, Xuan Qin, Rui Fu, Maosen Yang, Xin Hu, Shaorong Zhao, Yange Cui, Qingxiang Guo, Wei Zhou.  (2024)  Supramolecular nanodrug targeting CDK4/6 overcomes BAG1 mediated cisplatin resistance in oral squamous cell carcinoma.  JOURNAL OF CONTROLLED RELEASE,      [PMID:38479445] [10.1016/j.jconrel.2024.03.014]
28. Li Xiaoli, Wang Jiashuo, Guo Jiaxing, Zhang Ming.  (2025)  Targeting TNFAIP2 with NIR-II CRISPR-Cas9 nanosystem to overcome cisplatin resistance in laryngeal cancer.  npj Precision Oncology,  (1): (1-21).  [PMID:40731142] [10.1038/s41698-025-01054-w]
29. Ziqi Chen, Yaohua Ke, Junmeng Zhu, Lanqi Cen, Wenmei Rao, Sen Hong, Yan Wang, Jie Shao, Yanhong Chu, Xiaoping Qian, Baorui Liu, Rutian Li, Qin Liu.  (2025)  Biomineralized engineered Lactococcus lactis-based in situ vaccination enhances antitumor immunity via sequential activation of chemo-immunotherapy.  Journal for ImmunoTherapy of Cancer,  13  (8): (e011799).  [PMID:40819921] [10.1136/jitc-2025-011799]
30. Wei Zhu, Sai Zhu, Shan Jiang, Jiuyu Yin, Yonggui Wu, Xiaomei Luo.  (2025)  Paeoniflorin alleviates necroptosis in acute kidney injury induced by cisplatin and lansoprazole through targeting TNFAIP3.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:40779843] [10.1016/j.intimp.2025.115340]
31. Lu Jin, Yuanquan Ran, Nian Yang, Lanlan Yang, Xiaoyan Jia, Huan Zhao, Qiong Hu, Bing Yang, Dongxin Tang, Minyi Tian.  (2025)  Anti-Lung Cancer Effects and Related Mechanisms of α-Caryophyllene In Vitro and In Vivo.  Food Science & Nutrition,  13  (9): (e70862).  [PMID:40895140] [10.1002/fsn3.70862]
32. Jiaao Shen, Zijia Man, Weiwei Li, Mengqi Guo, Zefeng Xiang, Long Ma, Xianjiang Kang, Shuai Guo.  (2025)  Natural isoflavone sophoricoside emerges as a therapeutic candidate for lung cancer targeting TMEM16A ion channel.  PHYTOMEDICINE,      [PMID:41014666] [10.1016/j.phymed.2025.157289]
33. Xiong-Li Liu, Jing Lou, Xian-Qiao Zhu, Di-Cheng Pan, De-Wu Liu, Hui-Xian Jing, Wenjing Zhang, Hong-Xing Cen, Guo-Deng Guo-Deng Dong.  (2025)  Monodentate/bidentate chiral Ph/Py-NO ligands: an unexpected switch of enantioselectivity in Friedel-Crafts alkylation of indoles and 2,3-dioxopyrrolidines.  NEW JOURNAL OF CHEMISTRY,      [PMID:] [10.1039/D5NJ02472B]
34. Gaojian Liu, Wenjing Wen, Xuan Zhao, Yanan Jing, Hao Li, Xulong Fan, ZiXuan Huang, Gaofeng Liang.  (2025)  Enhanced ferroptosis by light-triggered biomimetic nano-erythrocyte membranes for tumor synergistic therapy.  NANOTECHNOLOGY,  36  (30): (305101).  [PMID:40697158] [10.1088/1361-6528/ade1de]
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36. Haoyu Yang, Xin Chen, Siqi Huang, Hongfang Dai, Zuowei Xiao, Jialong Fan, Honggang Zhang, Ke Du, Yan Qin.  (2025)  A novel GSH depletor for simultaneous ferroptosis and cuproptosis Activation in hepatocellular carcinoma.  BIOCHEMICAL PHARMACOLOGY,      [PMID:41173053] [10.1016/j.bcp.2025.117488]
37. Peinan Yin, Anamaria Brozovic, Wei Zhang, Chengwei Wu.  (2025)  Core–shell hydrogel microspheres with sequential drug release and magnetothermal synergy for drug-resistant ovarian cancer.  Biomaterials Science,      [PMID:41186349] [10.1039/D5BM01191D]
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41. Wenhao Zhou, Yijie Cai, Xilei Wang, Yijun Tu, Jiejuan Jiang, Jianqing Yu.  (2025)  Optimized extraction, isolation and identification of bioactive sesquiterpenes from Inula racemosa.  BIOORGANIC CHEMISTRY,      [PMID:41447946] [10.1016/j.bioorg.2025.109423]
42. Xiaoli Deng, Chunjie Hu, Lin Li, Guixian Yang, Chikun Li, Wanxun Zhang, Guangyu Cheng.  (2025)  Study on mechanism of action of β-elemene in inhibiting cisplatin resistance in lung cancer through LncRNA LINC00511.  Frontiers in Pharmacology,      [PMID:41480385] [10.3389/fphar.2025.1586657]
43. Alfaiz Faiz Abdulaziz.  (2025)  Biofabrication of chitosan-loaded gold nanoparticles: investigation of antimicrobial and anticancer activity and its morphological assessment in liver cancer cells.  NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY,      [PMID:41454954] [10.1007/s00210-025-04922-1]
44. Wei Dong, Wanlin Xie, Kun Song, Qunying Yuan, Peiyu Xi, Haoqun Fan, Lele Ma, Weidi Sun, Hui Zhang, Weihong Tan.  (2025)  A Membrane-Retained DNA Aptamer Promotes Intracellular Platinum Accumulation and Chemosensitization in Ovarian Cancer.  ACS Applied Materials & Interfaces,      [PMID:41461381] [10.1021/acsami.5c16889]
45. Qixiang Fang, Chengyu You, Xi Xiao, Yang Liu, Weiguang Yang, Qingchao Li, Liangliang Qing, Zhilong Dong.  (2025)  Mevalonate Metabolic Reprogramming Drives Cisplatin Resistance in Bladder Cancer: Mechanisms and Therapeutic Targeting.  PROTEIN AND PEPTIDE LETTERS,  32  (8): (597-609).  [PMID:40916434] [10.2174/0109298665403178250806111943]
46. Jianfa Wu, Huang Chen, Sihong Wang, Lei Peng, Xiaoying Hu, Zhou Liu.  (2025)  miR-512-3p/RPS6KA2 Axis Regulates Cisplatin Resistance in Ovarian Cancer via Autophagy and Ferroptosis.  ONCOLOGY RESEARCH,  34  (1): (26).  [PMID:41502518] [10.32604/or.2025.070542]
47. Sai-Nan Qin, Yi-Xue Zhang, Yi-Jie Cao, Ting Wan, Yi-Yang Zhou, Shan-Shan Su, Yu-Qiong Guo, Jian-Jun Sun, Kalle Salminen.  (2026)  A self-assembled electrochemical aptasensor for one-step rapid detection of cisplatin in blood via aptamer conformational change.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2026.116962]
48. Dong-Gui Guo, Lin-Lu Liu, Sijie Zhang, Hong-Xing Cen, Xiong-Li Liu, Hui-Juan Wang, Li-Jun Peng.  (2026)  Biomimetic synthesis of dispiro sesquiterpene lactone type of alkaloids and discovery of potential anticancer scaffolds.  NEW JOURNAL OF CHEMISTRY,      [PMID:] [10.1039/D5NJ04317D]
49. Bo Liu, Yaqin Tu, Xiangrui Li, Wenting Yu, Wenqing Zou, Wei Tang, Shimin Zong, Songwei Tan, Hongjun Xiao.  (2026)  Liposome-Encapsulated Rutin Attenuates Cisplatin-Induced Ototoxicity via Suppression of P53-Associated Oxidative Injury..  Biomaterials Research,      [PMID:41676218] [10.34133/bmr.0324]
50. Xiaoyi Cheng, Xiang-Fu Du, Jing Long, Yangyi Nie, Yuhan Du, Luyao Cheng, Cairong Li, Mei-Xia Zhao, Yuxiao Lai, Wei Zhang.  (2026)  Multifunctional cisplatin-loaded polydopamine/MnO2 nanomedicine circumvents drug resistant tumor microenvironment for enhanced chemo-photothermal therapy.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:41666770] [10.1016/j.colsurfb.2026.115505]
51. Ke Li, Zhengxiang Wang, Zaigang Zhou, Huan Ding, Sheng Wu, Yuan Li, Jianliang Shen.  (2026)  Mitochondria-Targeting Nanocuproptosis Breaks Immune Resistance.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202528750]
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