Clofibrate - Moligand™, 10mM in DMSO , Peroxisome proliferator-activated receptor alpha agonist, CAS No.637-07-0, Peroxisome proliferator-activated receptor alpha agonist

CAS: 637-07-0 Cat. No.: C408591 Fórmula: C₁₂H₁₅ClO₃ Peso molecular: 242.7 Beilstein Registry Number: 1913459 Número EC: 211-277-4

GRADE & PURITY Moligand™, 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Information

Clofibrate (Atromid-S), a fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia.
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Especificaciones y pureza

Moligand™, 10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Clofibrate (Atromid-S), a fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia. Clofibrate increases the activity of extrahepatic lipoprotein lipase (LL), thereby increasing lipop

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

AGONIST

Mecanismo de acción

Peroxisome proliferator-activated receptor alpha agonist

Propiedades del producto

• ALogP: 3.3

Nombres e identificadores

• Isómeros SMILES: CCOC(=O)C(C)(C)OC1=CC=C(C=C1)Cl
• WGK Alemania: 3
• RTECS: UE9480000
• Número ONU: 3082
• Peso molecular: 242.7
• Beilstein: 1913459
• Reaxy-Rn: 1913459
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1913459&ln=

Objetivos asociados (humanos)

PPARA Tclin Peroxisome proliferator-activated receptor alpha (1 Activities)

Discover Target: PPARA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Propiedades químicas y físicas

• Índice de refracción: 1.503
• Punto de inflamación (°F): 235.4 °F - closed cup
• Punto de inflamación (°C): 113 °C - closed cup
• Punto de ebullición (°C): 150 °C

Referencias

1. Cancan Duan, Weina Cheng, Qihong Chen, Xiaofei Li, Jianyong Zhang.  (2021)  Pharmacokinetics and tissue distribution of cantharidin after oral administration of aqueous extracts from Mylabris in rats.  BIOMEDICAL CHROMATOGRAPHY,  35  (10): (e5172).  [PMID:33982312] [10.1002/bmc.5172]

2. Ruijie Xie, Kaiheng Guo, Zhimin Ao, Ziyi Suo, Haibao Huang, DYC Leung.  (2023)  Surface-bound radicals generated from cobalt single-atom catalyst: Mechanism of boosting Fenton-like reactions.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2023.141920]

3. Hui Sun, Jianzhong Du.  (2018)  Plasmonic vesicles with tailored collective properties.  Nanoscale,  10  (36): (17354-17361).  [PMID:30198031] [10.1039/C8NR04820G]

Preguntas frecuentes

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 637-07-0, the molecular formula is C12H15ClO3, and the molecular weight is 242.7 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.