≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Cloperastine Hydrochloride: A GIRK Channels Inhibitor
Cloperastine Hydrochloride is a non-narcotic central antitussive agent with G protein-coupled inwardly rectifying K+ (GIRK) channels inhibitory effects. Recently, it has been reported GIRK channel inhibitors possess antidepressant-like action.
| Sonrisas canónicas | C1CCN(CC1)CCOC(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl |
|---|---|
| IUPAC Name | 1-[2-[(4-chlorophenyl)-phenylmethoxy]ethyl]piperidine;hydrochloride |
| InChIKey | UNPLRYRWJLTVAE-UHFFFAOYSA-N |
| INCHI | 1S/C20H24ClNO.ClH/c21-19-11-9-18(10-12-19)20(17-7-3-1-4-8-17)23-16-15-22-13-5-2-6-14-22;/h1,3-4,7-12,20H,2,5-6,13-16H2;1H |
| Isómeros SMILES | C1CCN(CC1)CCOC(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl |
| WGK Alemania | 3 |
| CAS alternativo | 3703-76-2 |
| PubChem CID | 161104 |
| Peso molecular | 366.32 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Clase | Benzene and substituted derivatives |
| Subclass | Diphenylmethanes |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Diphenylmethanes |
| Alternative Parents | Benzylethers Chlorobenzenes Piperidines Aryl chlorides Trialkylamines Dialkyl ethers Azacyclic compounds Organopnictogen compounds Organochlorides Hydrochlorides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Diphenylmethane - Benzylether - Chlorobenzene - Halobenzene - Aryl chloride - Aryl halide - Piperidine - Tertiary aliphatic amine - Tertiary amine - Azacycle - Dialkyl ether - Organoheterocyclic compound - Ether - Amine - Organohalogen compound - Organochloride - Organonitrogen compound - Organooxygen compound - Hydrochloride - Hydrocarbon derivative - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic heteromonocyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups. |
| External Descriptors | Not available |
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 D2403264 | Certificate of Analysis | Jan 19, 2026 | C489392 |
| D2403266 | Certificate of Analysis | Jan 19, 2026 | C489392 |
| D2403265 | Certificate of Analysis | Feb 24, 2024 | C489392 |
| D2403267 | Certificate of Analysis | Feb 24, 2024 | C489392 |
| H2511092 | Certificate of Analysis | Feb 24, 2024 | C489392 |
| Punto de fusión (°C) | 150.0 to 154.0 °C |
|---|---|
| Peso molecular | 366.300 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 6 |
| Exact Mass | 365.131 Da |
| Monoisotopic Mass | 365.131 Da |
| Topological Polar Surface Area | 12.500 Ų |
| Heavy Atom Count | 24 |
| Formal Charge | 0 |
| Complexity | 318.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |
