≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Clopidogrel thiolactone is an active metabolites containing thiols resulting from thionolactone transformation of clopidogrel . Clopidogrel thiolactone is a P2Y12 receptor inhibitor, is a potent antiplatelet agent
In Vivo
Clopidogrel thiolactone (8 μm/kg; i.v.; Sprague-Dawley male rats) has good biological availability and pharmacokinetic parameters . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Sprague-Dawley male rats Dosage: 8 μm/kg; orally clopidogrel (24 μm/kg) Administration: Intravenous injection; collected blood at 0 h (before dosing) and 0.083, 0.167, 0.5, 1, 2, 4, 6, 8, 24 h postdose. Result: 1.19 Parameter Clopidogrel C max (μg/L) 6.93 T max (h) 0.583 t 1/2 (h) 2.48 AUC 0-∞ (μg*h/L) 32.2
Form:Solid
IC50& Target:P2Y12 Receptor
| Isómeros SMILES | COC(=O)[C@H](C1=CC=CC=C1Cl)N2CCC3C(=CC(=O)S3)C2 |
|---|---|
| PubChem CID | 56848893 |
| Peso molecular | 337.82 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Solubilidad | DMSO : 50 mg/mL (148.01 mM; Need ultrasonic) Ethanol : 5 mg/mL (14.80 mM; ultrasonic and warming and heat to 40°C) |
|---|---|
| Peso molecular | 337.800 g/mol |
| XLogP3 | 2.600 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 4 |
| Exact Mass | 337.054 Da |
| Monoisotopic Mass | 337.054 Da |
| Topological Polar Surface Area | 71.900 Ų |
| Heavy Atom Count | 22 |
| Formal Charge | 0 |
| Complexity | 496.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
