Aldehyde dehydrogenase 1A (ALDH1A) inhibitor (IC50values are 0.64, 0.74 and 1.7 μM for ALDH1A3, ALDH1A2 and ALDH1A1, respectively). Induces a necroptotic phenotype and preferentially depletes CD133+ovarian cancer stem cellsin vitro.
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
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This compound belongs to the class of organic compounds known as benzimidazoles. These are organic compounds containing a benzene ring fused to an imidazole ring (five member ring containing a nitrogen atom, 4 carbon atoms, and two double bonds).
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
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