CMP-Sialic Acid, Monosodium Salt - ≥85% , CAS No.3063-71-6

CAS: 3063-71-6 Cat. No.: C350394 Peso molecular: 636.43

GRADE & PURITY ≥85%

Synonyms

D-glycero-beta-D-galacto-2-Nonulopyranosonic acid, 5-(acetylamino)-3,5-dideoxy-, 2-(hydrogen 5'-cytidylate) | CMP-N-acetylneuraminic acid | SCHEMBL23782673 | T8I6M8AXA0 | CMP acetylneuraminic acid | (2R,4S,5R,6R)-5-acetamido-2-[[(2R,3S,4R,5R)-5-(4-amino-2

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

CMP-sialic acid, Monosodium salt is the active form of sialic acid. In mammalian cells it has been shown to be required for the biosynthesis of sialic acid-containing complex carbohydrates. Loss of CMP sialic acid, Monosodium salt production or the feed back inhibitor of CMP-sialic acid has lead to gram scale production of sialic acid by GLCNE (GNE, UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase). The compound has demonstrated the ability to neutralize various toxins through masking binding sites. CMP-sialic acid, Monosodium salt has also provided protection against gonococci by siaylation of Gal beta 1-4GlcNAc group. Catalyzed through a surface sialyl-transferase, CMP-Sialic Acid, Monosodium Salt enhanced the responsiveness of insulin. The compound has also displayed function in blood protein half-life regulation, protection against glycoprotein lysis and cellular adhesion. CMP-Sialic Acid, Monosodium Salt is a substrate of Sialyltransferase.

Specifications

Sinónimos

D-glycero-beta-D-galacto-2-Nonulopyranosonic acid, 5-(acetylamino)-3, 5-dideoxy-, 2-(hydrogen 5'-cytidylate) | CMP-N-acetylneuraminic acid | SCHEMBL23782673 | T8I6M8AXA0 | CMP acetylneuraminic acid | (2R, 4S, 5R, 6R)-5-acetamido-2-[[(2R, 3S, 4R, 5R)-5-(4-amino-2

Especificaciones y pureza

≥85%

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥85%

Nombres e identificadores

• Sonrisas canónicas: CC(=O)NC1C(CC(OC1C(C(CO)O)O)(C(=O)O)OP(=O)(O)OCC2C(C(C(O2)N3C=CC(=NC3=O)N)O)O)O
• IUPAC Name: (2R,4S,5R,6R)-5-acetamido-2-[[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-4-hydroxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic acid
• InChIKey: TXCIAUNLDRJGJZ-HAOOPCFNSA-N
• INCHI: 1S/C20H31N4O16P/c1-7(26)22-12-8(27)4-20(18(32)33,39-16(12)13(29)9(28)5-25)40-41(35,36)37-6-10-14(30)15(31)17(38-10)24-3-2-11(21)23-19(24)34/h2-3,8-10,12-17,25,27-31H,4-6H2,1H3,(H,22,26)(H,32,33)(H,35,36)(H2,21,23,34)/t8-,9?,10+,12+,13?,14+,15+,16+,17+,20+/m0/s1
• Isómeros SMILES: CC(=O)N[C@@H]1[C@H](C[C@](O[C@H]1C(C(CO)O)O)(C(=O)O)OP(=O)(O)OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=CC(=NC3=O)N)O)O)O
• Peso molecular: 636.43
• Reaxy-Rn: 38498221
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=38498221&ln=

Propiedades químicas y físicas

• Solubilidad: Soluble in water.