Compound 48/80 , Agonist of MRGPRX2, CAS No.94724-12-6, Agonist of MRGPRX2

CAS: 94724-12-6 Cat. No.: C275407 PubChem CID: 76522018

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Descripción general

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Specifications

Mecanismos bioquímicos y fisiológicos

G protein activator; mast cell degranulator. Promotes histamine release, inhibits CaM (calmodulin), inhibits PLC (phospholipase C) and activates G proteins. Mechanism analogous to mastoparan . Active in vivo and in vitro .

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Desiccated

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

AGONIST

Mecanismo de acción

Agonist of MRGPRX2

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Nombres e identificadores

• Sonrisas canónicas: [HH].[HH].[HH].CNCCC1=CC(=C(C=C1)OC)CC2=CC(=CC(=C2OC)CC3=C(C=CC(=C3)CCNC)OC)CCNC.Cl.Cl
• IUPAC Name: 2-[4-methoxy-3-[[2-methoxy-3-[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-5-[2-(methylamino)ethyl]phenyl]methyl]phenyl]-N-methylethanamine;molecular hydrogen;dihydrochloride
• InChIKey: JBUOZOMGMXJHSP-UHFFFAOYSA-N
• INCHI: 1S/C32H45N3O3.2ClH.3H2/c1-33-14-11-23-7-9-30(36-4)26(17-23)21-28-19-25(13-16-35-3)20-29(32(28)38-6)22-27-18-24(12-15-34-2)8-10-31(27)37-5;;;;;/h7-10,17-20,33-35H,11-16,21-22H2,1-6H3;5*1H
• Isómeros SMILES: [HH].[HH].[HH].CNCCC1=CC(=C(C=C1)OC)CC2=CC(=CC(=C2OC)CC3=C(C=CC(=C3)CCNC)OC)CCNC.Cl.Cl
• CAS alternativo: 848035-21-2
• PubChem CID: 76522018

Objetivos asociados (humanos)

MRGPRX2 Tchem Mas-related G-protein coupled receptor member X2 (1 Activities)

Discover Target: MRGPRX2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Propiedades químicas y físicas

• Solubilidad: Soluble in water to 100 mM