Coumetarol - 10mM in DMSO , CAS No.4366-18-1

CAS: 4366-18-1 Cat. No.: C654823 Fórmula: C₂₁H₁₆O₇ Peso molecular: 380.35 PubChem CID: 54716150

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Coumetarol (Dicumoxane) is a vitamin K antagonist.

In Vitro

Coumetarol (Dicumoxane), an oral anticoagulant, is active in both models. The vitamin K antagonist Coumetarol is effective in both models after oral treatment but inhibits the thrombus formation more strongly in the arterio-venous shunt model. Treatment with the vitamin K antagonist Coumetarol in a dose of 25 mg/kg p.o. twice daily for 2 days results in a significant reduction in thrombus weight by 50% in the venous stasis model and by 75% in the arterio-venous shunt model. In both experiments the coagulation time as measured by the Thrombotest is prolonged to the same extent. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:vitamin K

Specifications

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Coumetarol (Dicumoxane) is a vitamin K antagonist.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

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Tipo de acción

ANTAGONIST

Nombres e identificadores

• Isómeros SMILES: COCC(C1=C(C2=CC=CC=C2OC1=O)O)C3=C(C4=CC=CC=C4OC3=O)O
• PubChem CID: 54716150
• Peso molecular: 380.35