Curcumin analog C1 - ≥97% , CAS No.39777-61-2

CAS: 39777-61-2 Cat. No.: C413625 Peso molecular: 294.34 Número EC: 873-543-1
Disponible para pedir
GRADE & PURITY ≥97%
Synonyms
MFCD00719180 | (1E,4E)-1,5-Bis(2-Methoxyphenyl)penta-1, | AB00092085-01 | TFEB activator 1 | D82401 | BDBM50285603 | TFEB activator 1; ABM-7612 | S6769 | 1,5-bis-(2-methoxyphenyl)-1,4-pentadien-3-one | 1,5-bis(2-methoxyphenyl)-1,4-pentadien-3-one | (1E,4E
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
5mg
C413625-5mg
1
78,90US$
10mg
C413625-10mg
3
125,90US$
25mg
C413625-25mg
2
278,90US$
50mg
C413625-50mg
2
452,90US$
100mg
C413625-100mg
1
657,90US$
200mg
C413625-200mg
2
1.049,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Information

Curcumin analog C1 (Curcumin analog Compound C1) is a potenttranscription factor EB (TFEB)activator with promise for the prevention or treatment of Alzheimer's disease.

Specifications

Sinónimos
MFCD00719180 | (1E, 4E)-1, 5-Bis(2-Methoxyphenyl)penta-1, | AB00092085-01 | TFEB activator 1 | D82401 | BDBM50285603 | TFEB activator 1; ABM-7612 | S6769 | 1, 5-bis-(2-methoxyphenyl)-1, 4-pentadien-3-one | 1, 5-bis(2-methoxyphenyl)-1, 4-pentadien-3-one | (1E, 4E
Especificaciones y pureza
≥97%
Mecanismos bioquímicos y fisiológicos
TFEB activator 1 is an orally effective, mTOR-independent activator of TFEB. TFEB activator 1 significantly promotes the nuclear translocation of Flag-TFEB with an EC50 of 2167 nM. TFEB activator 1 enhances autophagy without inhibiting the mTOR pathway an
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Pureza
≥97%
Nombres e identificadores
Pubchem Sid504760246
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504760246
Sonrisas canónicasCOC1=CC=CC=C1C=CC(=O)C=CC2=CC=CC=C2OC
IUPAC Name(1E,4E)-1,5-bis(2-methoxyphenyl)penta-1,4-dien-3-one
InChIKeyRCZMPCUUTSDNAJ-PHEQNACWSA-N
INCHI1S/C19H18O3/c1-21-18-9-5-3-7-15(18)11-13-17(20)14-12-16-8-4-6-10-19(16)22-2/h3-14H,1-2H3/b13-11+,14-12+
Isómeros SMILES COC1=CC=CC=C1/C=C/C(=O)/C=C/C2=CC=CC=C2OC
Peso molecular 294.34
Reaxy-Rn 2335342
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2335342&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClasePhenol ethers
SubclassAnisoles
Intermediate Tree Nodes Not available
Direct ParentAnisoles
Alternative Parents Styrenes  Phenoxy compounds  Methoxybenzenes  Alkyl aryl ethers  Enones  Acryloyl compounds  Ketones  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Phenoxy compound - Anisole - Styrene - Methoxybenzene - Alkyl aryl ether - Monocyclic benzene moiety - Enone - Acryloyl-group - Alpha,beta-unsaturated ketone - Ketone - Ether - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Organic oxide - Organic oxygen compound - Aromatic homomonocyclic compound
DescripciónThis compound belongs to the class of organic compounds known as anisoles. These are organic compounds containing a methoxybenzene or a derivative thereof.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
HL-60 (67320 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RPMI-7951 (420 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KB (17409 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HeLa (62764 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDA-MB-231 (73002 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Luciferin 4-monooxygenase (66902 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeFechaArticulo
J2214467Certificate of AnalysisJul 10, 2025 C413625
J2214499Certificate of AnalysisJul 10, 2025 C413625
J2214531Certificate of AnalysisJul 10, 2025 C413625
J2214532Certificate of AnalysisJul 10, 2025 C413625
J2214533Certificate of AnalysisJul 10, 2025 C413625
J2214534Certificate of AnalysisJul 10, 2025 C413625
Propiedades químicas y físicas
SolubilidadDMSO: 59 mg/mL (200.45 mM)Ethanol: 2 mg/mL (6.79 mM)
Peso molecular294.300 g/mol
XLogP34.100
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count6
Exact Mass294.126 Da
Monoisotopic Mass294.126 Da
Topological Polar Surface Area35.500 Ų
Heavy Atom Count22
Formal Charge0
Complexity363.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds2
Covalently-Bonded Unit Count1
Calculadoras de soluciones
Reseñas

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