CVN636 , CAS No.2226732-62-1

CAS: 2226732-62-1 Cat. No.: C651356 Fórmula: C₁₉H₂₀FNO₄S Peso molecular: 377.43 PubChem CID: 134521670

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

CVN636 is a potent, orally active and selective mGluR7 allosteric agonist with an EC 50 value of 7 nM for hu mGluR7 . CVN636 has central nervous system (CNS) permeability

In Vivo

CVN636 (0.3-3 mg/kg; p.o.) reduces ethanol self-administration in msP rats . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: msP rat Dosage: 0.3, 1, and 3 mg/kg Administration: oral administration Result: Reduced alcohol self-administration in a dose-dependent.

IC50& Target:hu mGluR7 7 nM (EC 50 )

Especificaciones

Mecanismos bioquímicos y fisiológicos

CVN636 is a potent, orally active and selective mGluR7 allosteric agonist with an EC 50 value of 7 nM for hu mGluR7 . CVN636 has central nervous system (CNS) permeability.

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

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Tipo de acción

AGONIST

Nombres e identificadores

Isómeros SMILES

C[C@@H](C1=CC=C(C=C1)F)C(=O)N[C@H]2COC3=CC=CC=C3[C@@H]2S(=O)(=O)C

PubChem CID

134521670

Peso molecular

377.43